At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

Rising young comedian Moshe Kasher is lucky to be alive. He started using drugs when he was just 12. At that point, he had already been in psychoanlysis for 8 years. By the time he was 15, he had been in and out of several mental institutions, drifting from therapy to rehab to arrest to...you get the picture. But Kasher in the Rye is not an "eye opener" to the horrors of addiction. It's a hilarious memoir about the absurdity of it all.

You get ready to die the way you get ready for a trip. Start by realizing you don't know the way. Listen to a few travel guides. Study the language, look at maps, gather equipment. Let yourself imagine what it will be like. Pack your bags. This book is one of those travel guides - a guide to preparing for your own death and the deaths of people close to you. The fact of death is hard to believe. Sallie Tisdale explores our fears and all the ways death and talking about death make us uncomfortable - but she also explores its intimacies and joys.

Anna was living a normal life. She was ambitious and worked hard; she had just bought an apartment; she was falling in love. But then she started to develop worrying symptoms: her face felt like it was burning whenever she was in front of the computer. Soon this progressed to an intolerance of fluorescent light, then of sunlight itself. The reaction soon spread to her entire body.

Meet Harold Fry, recently retired. He lives in a small English village with his wife, Maureen, who seems irritated by almost everything he does, even down to how he butters his toast. Little differentiates one day from the next. Then one morning the mail arrives, and within the stack of quotidian minutiae is a letter addressed to Harold in a shaky scrawl from a woman he hasn’t seen or heard from in twenty years. Queenie Hennessy is in hospice and is writing to say goodbye.

Regarded as one of the finest journalists of her generation, Mamie Baird Magnusson's whole life was a celebration of words - words that she fought to retain in the grip of a disease which is fast becoming the scourge of the 21st century. Married to writer and broadcaster Magnus Magnusson, they had five children of whom Sally is the eldest.

They all thought he was gone. But he was alive and trapped inside his own body for ten years. In January 1988 Martin Pistorius, aged 12, fell inexplicably sick. First, he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within 18 months, he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.

When the partner of Emmy Award–winning screenwriter Abi Morgan abruptly collapsed from a mysterious illness, doctors were concerned that he would not survive. Then, six months later, Jacob woke from his coma, to the delight and relief of his family and friends—except this proved to be anything but a Hollywood ending. Because to Jacob, the woman standing at his bedside, who had cared for him all these months, was not his partner. Not his children’s mother. Not the woman he loved. Sure, she looked like his Abi, but this was an imposter, living someone else’s life.

Wendy Mitchell had a busy job with the British National Health Service, raised her two daughters alone, and spent her weekends running and climbing mountains. Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn’t know it then, but dementia was starting to take hold. In 2014, at age 58, she was diagnosed with young-onset Alzheimer’s. In this groundbreaking book, Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off.

New York Times best-selling author Ian McEwan's novels have inspired sweeping critical acclaim and won such prestigious awards as the Booker Prize for Amsterdam and the National Book Critics Circle Award for his modern masterpiece, Atonement. With Saturday, McEwan has crafted perhaps his most unique achievement to date.

In anticipation of her 38th birthday, Katherine May set out to walk the 630-mile South West Coast Path. She wanted time alone, in nature, to understand why she had stopped coping with everyday life; why motherhood had been so overwhelming and isolating; and why the world felt full of expectations she couldn't meet. She was also reeling from a chance encounter with a voice on the radio that sparked her realisation that she might be autistic.

In the summer of 1992, on the eve of an American tour, Ben Watt, one half of the Billboard-topping pop duo Everything but the Girl, was taken to a London hospital complaining of chest pain. He didn't leave for two and a half months. Watt had developed a rare life-threatening disease that initially baffled doctors. By the time he was allowed home, his ravaged body was 46 pounds lighter, and he was missing most of his small intestine.

Following up her international best seller The Zookeeper's Wife, Diane Ackerman tells the breathtaking story of the stroke that deprived her husband, Paul West - a distinguished novelist and poet - of every scrap of language beyond the syllable "mem". In her characteristically glorious prose, Ackerman weaves together the latest science on stroke and the brain’s ability to store and process language, with her intensely personal journey as caregiver in helping Paul to an extraordinary recovery.

I Am, I Am, I Am is Maggie O'Farrell's astonishing memoir of the near-death experiences that have punctuated and defined her life. The childhood illness that left her bedridden for a year, which she was not expected to survive. A teenage yearning to escape that nearly ended in disaster. An encounter with a disturbed man on a remote path. And, most terrifying of all, an ongoing, daily struggle to protect her daughter - for whom this book was written - from a condition that leaves her unimaginably vulnerable to life's myriad dangers.

Russia, 1986: On a run-down apartment block in Moscow, a nine-year-old prodigy plays his piano silently for fear of disturbing the neighbors. In a factory on the outskirts of the city, his aunt makes car parts, hiding her dissident past. In a nearby hospital, a surgeon immerses himself in his work, avoiding his failed marriage. And in a village in Belarus, a teenage boy wakes to a sky of the deepest crimson. Outside, the ears of his neighbor's cattle are dripping blood. Ten miles away, at the Chernobyl Power Plant, something unimaginable has happened.

In anticipation of her 38th birthday, Katherine May set out to walk the 630-mile South West Coast Path. She wanted time alone, in nature, to understand why she had stopped coping with everyday life; why motherhood had been so overwhelming and isolating; and why the world felt full of expectations she couldn't meet. She was also reeling from a chance encounter with a voice on the radio that sparked her realisation that she might be autistic.

When Dorrit Wegner turned fifty, the government transferred her to a state-of-the-art facility where she can live out her days in comfort. Her apartment is furnished to her tastes, her meals expertly served, and all at the very reasonable non-negotiable price of one cardiopulmonary system. Once an outsider without family, derided by a society bent on productivity, Dorrit finds within The Unit the company of kindred spirits and a dignity conferred by 'use' in medical tests.

When Simon Serrailler was a rookie constable with the Met, he did something reckless in the course of a night's work which caused a man's death. But his act was praised by his colleagues, and he was called a hero. Years later, now a detective chief superintendent who has been badly injured in the course of duty, he receives a medal for bravery at Buckingham Palace while recollecting that fateful night of his early career, when chance disguised itself as bravery.

When an industrial accident unleashes an "airborne toxic event", a lethal black chemical cloud floats over the Gladneys' lives. The menacing cloud is a more urgent and visible version of the "white noise" engulfing the Gladneys - radio transmissions, sirens, microwaves, ultrasonic appliances, and TV murmurings - pulsing with life yet suggesting something ominous.

In the spirit of Zoë Heller’s Notes on a Scandal and Tom Perrotta’s Mrs. Fletcher, an explosive and thought-provoking novel about the far-reaching repercussions of an illicit relationship between a young girl and a man 20 years her senior. Masterfully told from three diverse viewpoints - victim, perpetrator, and witness - Putney is a subtle and enormously powerful novel about consent, agency, and what we tell ourselves to justify what we do, and what others do to us.

Successful journalist Erin Kelly has electrified readers and critics alike with her debut novel The Poison Tree. In this scintillating work, Karen and her daughter Alice have established a safe, happy life free from the madness of Karen’s past. But when Karen’s former lover Rex is released from prison, her old associations intrude upon the present - and threaten everything she holds dear.

For Gideon Mack, faithless minister, unfaithful husband, and troubled soul, the existence of God, let alone the Devil, is no more credible than that of ghosts or fairies - until the day he falls into a gorge and is rescued by someone who might just be Satan.

Jenny is a successful family doctor, the mother of three great teenagers, married to a celebrated neurosurgeon. But when her youngest child, 15-year-old Naomi, doesn't come home after her school play, Jenny's seemingly ideal life begins to crumble. The authorities launch a nationwide search with no success. Naomi has vanished, and her family is broken.

When Mark Doty went looking to adopt a small dog, a cuddly creature who might comfort his terminally ill partner, Wally Roberts, he was surprised to find himself returning home from an animal shelter with a full-grown golden retriever, a dog whose "absolute openess of regard", and paw gently offered through the bars of a cage, proved irresistable to him.

For almost a decade, Rachel Caine has turned her back on home, kept distant by family disputes and her work monitoring wolves on an Idaho reservation. But now, summoned by the eccentric Earl of Annerdale and his controversial scheme to reintroduce the grey wolf to the English countryside, she is back in the peat and wet light of the Lake District. The earl's project harks back to an ancient idyll of untamed British wilderness.

The new novel by the author of the best-selling The World Walker series. 'My name is Daniel Harbin, and I'm a child of The Deterrent.' What if a superhuman turned out not to be so super...or even human? Britain's superhero, The Deterrent, was unveiled to the world in 1979 and disappeared two years later. The truth about his origins has never been revealed. The rumours about his children - those that survived - and their mysterious abilities have never been confirmed. Until now....

With more than 30 million copies of his works published, in 37 languages, award-winning author Henning Mankell may be Sweden's most accomplished novelist. Here he crafts the icy, atmospheric tale of Fredrik Welin, a disgraced surgeon living in exile on a small island. When Fredrik receives a surprise visit from a lover he abandoned decades earlier, he begins the difficult road to redemption.

Since the publication of his first novel 30 years ago, Don DeLillo has lived in the skin of our times. He has found a voice for the forgotten souls who haunt the fringes of our culture and for its larger-than-life real figures. The Body Artist is DeLillo's haunting and profoundly moving new novel.

When a house explodes in a quiet Oxford suburb and a young girl disappears in the aftermath, Sarah Tucker becomes obsessed with finding her. Accustomed to dull chores in a childless household and hosting her husband’s wearisome business clients for dinner, Sarah suddenly finds herself questioning everything she thought she knew, as her investigation reveals that people long believed dead are still among the living, while the living are fast joining the dead.

In the last year, the narrator of 10:04 has enjoyed unexpected literary success, has been diagnosed with a potentially fatal heart condition, and has been asked by his best friend to help her conceive a child, despite his dating a rising star in the visual arts. In a New York of increasingly frequent super storms and political unrest, he must reckon with his biological mortality, the possibility of a literary afterlife, and the prospect of (unconventional) fatherhood in a city that might soon be under water.