Joe, a recent divorcee, takes his wrestling-mad son Danny to the zoo for his weekend of custody. Everything is going great until a bizarre snake attack sends everybody running for cover. A horrific scene, and one Joe's poor son is unlikely ever to forget... But the terror has only just begun. A simple snake attack is only the first incident in an unstoppable catastrophe. Something is causing animals to attack people... to think for themselves... to thirst for blood.

Exhausted from an endless series of rescue operations, U.S.M.C. Corporal Reimer is recruited into a special task force. The mission is crucial: Rescue a government researcher who has developed a cure for the infection.

Our survivors, separated and on the loose, find themselves surrounded by the dead and the living. Still trying to find their way, they bind themselves to each other through blood and bullets. Good news for them, bad news for anyone who gets in their way… because these bikes run on blood!

Riding her Soul Horse, Danny, Deirdre Buford relentlessly pursues the men who took her sister through an America wrecked by the Great Virus, endless civil war and a collapse of the global order called the Breakdown. She’s forced by circumstances to ally with a nomadic photographer. His gentle decency moves her to the core, but her mission leads her away from the man she’s falling in love with and toward a confrontation with the people who hold her sister. To defeat them, she’ll need the help of the powerful Nations, a league of indigenous tribes.

The power goes out in a small city in Northern Ontario, unbeknownst to the rest of the world. Darkness engulfs the entire district of Lex, trapping its inhabitants within invisible boundaries. The De Cree prepare for their first step towards taking over control. The Greater City of Lex is only the beginning. A common goal brings together strangers. Survival. Uniting them despite their differences. When faced with tough decisions, the remaining inhabitants of Lex must challenge themselves to discover their true abilities.