For much of his career, Dr. Mark Epstein kept his beliefs as a Buddhist separate from his work as a psychiatrist. But as he became more forthcoming with his patients about his personal spiritual leanings, he was surprised to find how many of them were eager to learn more. The divisions between the psychological, emotional, and the spiritual, he soon realized, were not as distinct as one might think.

As a single mother, Annie has an especially close relationship with her son, Ben. They have always been together. Just the two of them. So, when Ben brings home his mysterious beautiful new wife, Daisy, immediately Annie doesn’t trust her. Who is this woman who has taken her son away from her? And what is she hiding? She’ll protect him with her life....

When Nancy Hennessy is murdered, she leaves behind two best friends, an adoring husband and daughter, and a secret lover whose identity she took to the grave. Nancy was gorgeous, wealthy, and cherished by those who knew her - from the outside, her life was perfect. But as the investigation into her death flounders and her friends Eleanor and Mary wrestle with their grief, dark details surface that reveal how little they knew their friend, each other, and maybe even themselves.

Talking about death and dying is considered taboo in polite company, and even in the medical field. Our ideas about dying are confusing at best: Will our memories flash before our eyes? Regrets consume our thoughts? Does a bright light appear at the end of a tunnel? For most people, it will be a slower process, one eased with preparedness, good humor, and a bit of faith. At the forefront of changing attitudes around palliative care is hospice nurse Hadley Vlahos, who shows that end-of-life care can teach us just as much about how to live as it does about how we die.

Somewhere out beyond the edge of the universe there is a library that contains an infinite number of books, each one the story of another reality. One tells the story of your life as it is, along with another book for the other life you could have lived if you had made a different choice at any point in your life. While we all wonder how our lives might have been, what if you had the chance to go to the library and see for yourself? Would any of these other lives truly be better? In The Midnight Library, Nora Seed finds herself faced with this decision.

The doorbell rings, just days after my beloved husband’s sudden death. I don’t recognise the woman on our doorstep, with her blonde highlights, a diamond bracelet identical to my own and a bouncing baby boy in her arms. As I show her inside, I notice her eyes grow wide as she takes in our spacious hallway, and the big squashy sofas that we all used to pile on. She glances at the silver-framed family photos and my little daughter hiding behind my skirts. She looks at me, her blue eyes serious. ‘I’m sorry’ she says. ‘I am your husband’s girlfriend. And this is his son.'

Josef Breuer, one of the founding fathers of psychoanalysis, is at the height of his career. Friedrich Nietzsche, Europe's greatest philosopher, is on the brink of suicidal despair, unable to find a cure for the headaches and other ailments that plague him. When he agrees to treat Nietzsche with his experimental "talking cure", Breuer never expects that he, too, will find solace in their sessions. Only through facing his own inner demons can the gifted healer begin to help his patient.

Meet Tom. Or Dr O’Grady, as he used to be called. When you pass him on the street, most people don’t even give him a second glance. You see, Tom isn’t living his best life. Burdened by grief, he’s only got his loyal dog, Bette Davis, for company and a rucksack containing his whole world. Then there’s Ruth and her son, DJ, who no longer have a place to call home. But Ruth believes that you can change the world by helping one person at a time - and Tom needs her help. There are a thousand ways to find your home - you just need to be brave enough to look for them.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

When PhD candidate Sarah Vallance is thrown from a horse and suffers a jarring blow to the head, she believes she walks away unscathed. The next morning, things take a sharp turn as she’s quickly led from work to the emergency room. By the end of the week, a neurologist delivers a devastating prognosis: Sarah suffered a traumatic brain injury that has caused her IQ to plummet, with no hope of recovery. Her brain has irrevocably changed.

Ten years ago, Helen Naylor discovered her mother, Elinor, had been faking debilitating illnesses for 30 years. After Elinor’s self-induced death, Helen found her diaries, which Elinor wrote daily for more than 50 years. The diaries reveal not only the inner workings of Elinor’s twisted mind and self-delusion, but also shocking revelations about Helen’s childhood. Everything Helen knew about herself and her upbringing was founded on a lie.

Ten years ago, Grace made her dying sister a promise - that she would look after Hope’s baby son as her own. Now, the man whose son she is raising has turned up on Grace’s operating table, fighting for his life. When an accusation of negligence follows, Grace is forced to confront not just the man who abandoned her sister, but also his mother, Norma - who blames Grace for taking everything she loves. Based on what her sister told her, Grace is sure she did the right thing to keep that promise. But what if Hope didn’t tell her everything?

In Massachusetts, neuroscience students Luke, Josh, and Hope have formed an unbreakable and unconditional friendship. Bound by their wit, brilliance, and curiosity, they throw themselves heart and soul into their research. Their new computer program can capture a person’s entire consciousness, memory, and personality - a digital map of the brain’s connections that promises to bridge the relationship between human and machine, between the past and the future. When Hope is diagnosed with a fatal and aggressive illness, their work takes on a new significance and urgency.

There’s a cottage on a cliff. Gabe and Pippa’s dream home in a sleepy coastal town. But their perfect house hides something sinister. The tall cliffs have become a popular spot for people to end their lives. Night after night Gabe comes to their rescue, literally talking them off the ledge. Until he doesn’t. When Pippa discovers Gabe knew the victim, the questions spiral...Did the victim jump? Was she pushed?

Jillian Horton, a general internist, has no idea what to expect during her five-day retreat at Chapin Mill, a Zen centre in upstate New York. She just knows she desperately needs a break. At first she is deeply uncomfortable with the spartan accommodations, silent meals, and scheduled bonding sessions. But as the group struggles through awkward first encounters and guided meditations, something remarkable happens: World-class surgeons, psychiatrists, pediatricians and general practitioners open up and share stories about their secret guilt and grief.