In Creative Quest, Questlove synthesizes all the creative philosophies, lessons, and stories he's heard from the many creators and collaborators in his life, and reflects on his own experience, to advise listeners and fans on how to consider creativity and where to find it. He addresses many topics - what it means to be creative, how to find a mentor and serve as an apprentice, the wisdom of maintaining a creative network, coping with critics and the foibles of success, and the specific pitfalls of contemporary culture.

Meet Preach, Digit, and Maria, three lost and damaged souls trying to make it on the streets of New York City, running petty scams to stay alive. A twist of events changes their lives forever when they accidently kill a man connected to the mob and find a small fortune. Now on the run, the trio tries to escape a notorious hit man called B-Boy. Along the way, they run into more shady characters and more trouble. Seduced by the siren call of the money and struggling with their own demons, Preach, Digit, and Maria will soon discover even the closest bonds can't overcome their past traumas.

Ike Randolph has been out of jail for fifteen years, with not so much as a speeding ticket in all that time. But a Black man with cops at the door knows to be afraid. The last thing he expects to hear is that his son Isiah has been murdered, along with Isiah’s white husband, Derek. Ike had never fully accepted his son but is devastated by his loss. Derek’s father Buddy Lee was almost as ashamed of Derek for being gay as Derek was ashamed his father was a criminal. Buddy Lee still has contacts in the underworld, though, and he wants to know who killed his boy.

Beauregard "Bug" Montage is an honest mechanic, a loving husband, and a hardworking dad. Bug knows there's no future in the man he used to be: Known from the hills of North Carolina to the beaches of Florida as the best wheelman on the East Coast. He thought he'd left all that behind him, but as his carefully built new life begins to crumble, he finds himself drawn inexorably back into a world of blood and bullets. When a smooth-talking former associate comes calling with a can't-miss jewelry store heist, Bug feels he has no choice but to get back in the driver's seat.

Titus Crown is the first Black sheriff in the history of Charon County, Virginia. In recent decades, quiet Charon has had only two murders. But after years of working as an FBI agent, Titus knows better than anyone that while his hometown might seem like a land of moonshine, cornbread, and honeysuckle, secrets always fester under the surface. Then a year to the day after Titus’s election, a school teacher is killed by a former student and the student is fatally shot by Titus’s deputies. As Titus investigates the shootings, he unearths terrible crimes.