An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

Talking about death and dying is considered taboo in polite company, and even in the medical field. Our ideas about dying are confusing at best: Will our memories flash before our eyes? Regrets consume our thoughts? Does a bright light appear at the end of a tunnel? For most people, it will be a slower process, one eased with preparedness, good humor, and a bit of faith. At the forefront of changing attitudes around palliative care is hospice nurse Hadley Vlahos, who shows that end-of-life care can teach us just as much about how to live as it does about how we die.

At the University of Wisconsin, Dr. Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.

Carson Chow is a high functioning addict. For years, he's been able to meet the increasing demands from his aging immigrant parents while hiding his crystal meth use every other weekend. One Friday night, as he's passed out from a drug binge, he misses 38 phone calls from his father, detailing first the collapse and eventually the death of his mother. Carson has always been close to his mother. He throws himself into the preparation of his mother's funeral. Will this tragedy plunge him deeper into his abuse or finally rouse him from his addiction stupor?

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

Now in its third edition, Stronger After Stroke gives the power of recovery to the listeners by providing simple-to-follow instructions for reaching the highest possible level of recovery. The audiobook's neuroplastic recovery model stresses repetition of task-specific practice, proper scheduling of practice, setting goals, and measuring progress to achieve optimal results. Researcher Peter G. Levine breaks down the science and gives survivors evidence-based tools to retrain the brain and take charge of recovery.

In My Stroke of Insight, Taylor shares her unique perspective on the brain and its capacity for recovery, and the sense of omniscient understanding she gained from this unusual and inspiring voyage out of the abyss of a wounded brain. It would take eight years for Taylor to heal completely. Because of her knowledge of how the brain works, her respect for the cells composing her human form, and most of all an amazing mother, Taylor completely repaired her mind and recalibrated her understanding of the world.

So begins Chloé Cooper Jones’s bold, revealing account of moving through the world in a body that looks different than most. Jones learned early on to factor “pain calculations” into every plan, every situation. Born with a rare congenital condition called sacral agenesis which affects both her stature and gait, her pain is physical. But there is also the pain of being judged and pitied for her appearance, of being dismissed as “less than.”

The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson's Research, the world's leading nonprofit funder of PD science.

In Mary Beth Keane's extraordinary novel, a lifelong friendship and love blossoms between Kate Gleeson and Peter Stanhope, born six months apart. One shocking night their loyalties are divided, and their bond will be tested again and again over the next 30 years. Heartbreaking and redemptive, Ask Again, Yes is a gorgeous and generous portrait of the daily intimacies of marriage and the power of forgiveness....

Eleven-year-old Anna has lived all her life with severe epilepsy. Despite the ravage of thousands of violent seizures and heavy medications, she has thrived at school, athletics, and her greatest passion—dance. As she approaches her twelfth birthday, Anna's condition takes a dire turn. Her health declines quickly and a new diagnosis is revealed, leaving the family only one excruciating choice.

True Grit and Grace tells the story of a woman's life forever altered by a horrific motorcycle accident that shattered her right leg. Despite the initial recommendation to amputate, she endured 34 surgeries to save it. However, as a sexual-abuse and divorce survivor, she determined to save not only her leg, but her career, her dreams, and her dignity.

In an audiobook that is The Big Sick meets Dad Is Fat, Jeannie Gaffigan, writer/director/producer/accused supermom and wife of best-selling author/comedian Jim Gaffigan, writes with humor and heart about the pear-sized brain tumor she had removed, the toll it took on her enormous family, and the priceless lessons she learned along the way.

We've all had to make decisions in our lives about what to keep and what to toss—habits, attitudes, friends, even homes. In this new collection of essays, Elizabeth Passarella explores the ups and downs of moving forward—both emotionally and logistically—with her welcome candor and sense of humor that listeners have come to love. It Was an Ugly Couch Anyway will make listeners laugh, cry, and feel a little less alone as they navigate their own lives that are filled with uncertainty, change, and things beyond their control.

After being diagnosed in her early forties with metastatic melanoma - a "rapidly fatal" form of cancer - journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own - with very different results.

In an idyllic Los Angeles neighborhood, where generations enjoy deep roots in old homes, the O’Rourke family fits right in. Miriam and Craig are both artists and their four children carry on the legacy. When their teenage son, Nick, is diagnosed with schizophrenia, a tumultuous decade ensues in which the family careens off the conventional course. Like the 10 Biblical plagues, they are hit by one catastrophe after another: violence, evictions, arrests, a suicide attempt, a near-drowning - even cancer and a brain tumor - play against the backdrop of a wild teenage bacchanal.

Iron Cowboy is an endurance memoir in the tradition of Dean Karnazes’s Ultramarathon Man - a lifetime’s worth of intensely lived experience packed into 20 riveting chapters. Listeners will discover the secret to redefining their own goals and achieving great success. When James Lawrence (aka the Iron Cowboy) announced his plan to complete 50 full-distance triathlons in 50 consecutive days in all 50 states, the only person who believed that he could pull it off was James himself (and his wife, Sunny).

Julia Fox Garrison refused to listen to the professionals she called Dr. Jerk and Dr. Panic, who - after she suffered a massive, debilitating stroke at age thirty-seven - told her she’d probably die, or to Nurse Doom, who ignored her emergency call button. Instead she heeded the advice of kind, gifted Dr. Neuro, who promised her he would “treat your mind as well as your body.” Julia figured if she could somehow manage to get herself into a wheelchair, at least she’d always find parking. But after many, many months of hospitalization and rehab, Julia not only got into a wheelchair, but she got back out.

True Grit and Grace tells the story of a woman's life forever altered by a horrific motorcycle accident that shattered her right leg. Despite the initial recommendation to amputate, she endured 34 surgeries to save it. However, as a sexual-abuse and divorce survivor, she determined to save not only her leg, but her career, her dreams, and her dignity.

A 25-year-old backcountry wanderer, a man happiest exploring wild places with his dog, Dan Bigley woke up one midsummer morning to a day full of promise. Before it was over, after a stellar day of salmon fishing along Alaska’s Kenai and Russian rivers, a grizzly came tearing around a corner in the trail. Dan barely had time for “bear charging” to register before it had him on the ground, altering his life forever.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

Imagine a young doctor, trained in the latest medical knowledge and state-of-the-art equipment, suddenly transported back to one of the world’s most isolated and unforgiving environments - Nome, Alaska. That’s what happen to Dr. Sims. His plans to become a pediatric surgeon were drastically changed when, on the eve of being drafted into the army to serve as a MASH surgeon in Vietnam, he was offered a commission in the US Public Health for assignment in Anchorage, Alaska, where he was scheduled to act as chief of pediatrics at the Alaska Native Medical Center.

At first, Ken Abraham wrote off his mother’s changes in behavior as quirks that just come with old age. There was memory loss, physical decline, hygiene issues, paranoia, and uncharacteristic attitudes. He soon realized that dementia had changed her life - and his family’s - forever. According to the Alzheimer’s Association, an estimated 5.4 million Americans of all ages have Alzheimer’s disease. That’s one in eight older Americans. More than likely, that figure includes someone you know and love.

The 1980s marked a revolution in the field of organ transplants, and Bud Shaw, MD, who studied under Tom Starzl in Pittsburgh, was on the front lines. Now retired from active practice, Dr. Shaw relays gripping moments of anguish and elation, frustration and reward, despair and hope in his struggle to save patients. He reveals harshly intimate moments of his medical career.

Dr. Kathy Magliato is one of fewer than a dozen female heart surgeons practicing in the world today. She is also a member of an even more exclusive group - those surgeons who perform heart transplants. Healing Hearts is the story of the making of a surgeon who also calls herself a wife and mother.

Here, Michael Palmer has created a cat-and-mouse game where one woman must confront a conspiracy of doctors to uncover an evil practice that touches every single person who ever has a medical test. With unforgettable characters and twists and betrayals that come from the most unlikely places, The Second Opinion will keep you guessing...and looking over your shoulder.

At forty years old, a successful writer, husband and father, no longer toiling on offshore drilling rigs, was Paul Carter happily nestled in the cotton wool of suburban life enjoying the fruits of his labour? Was he f**k! With his manic life left far behind and the perfect opportunity to take it easy stretched before him what else would a middle-aged, bike obsessed, man want? Yes, that's right, he'd want to be the first guy to ride around Australia on an underpowered experimental motorcycle that runs on used cooking oil, wouldn't he? Preferably without getting hit by a semi-trailer full of bridge parts.

With his signature acerbic wit and hilarious voice, 20-something author, blogger, and entrepreneur Shane Burcaw is back with an essay collection about living a full life in a body that many people perceive as a tragedy. From anecdotes about first introductions where people patted him on the head instead of shaking his hand, to stories of passersby mistaking his able-bodied girlfriend for a nurse, Shane tackles awkward situations and assumptions with humor and grace.

Heartwarming and gloriously eccentric, Dr Tom's stories capture the beauty of the Lowlands, the joys and sorrows of its inhabitants and the richly rewarding experiences of life as a Scottish country doctor.

At age nine, Josh Sundquist was diagnosed with cancer, and by age 10, he'd lost his leg to the illness. But Sundquist never faltered in his dream to ski in the Paralympics, and in 2006 he achieved his goal in Turin, Italy.