From blurry vision to crooked teeth, ACLs that tear at alarming rates and spines that seem to spend a lifetime falling apart, it's a curious thing that human beings have beaten the odds as a species. After all, we're the only survivors on our branch of the tree of life. Why is it that human mothers have such a life-endangering experience giving birth? And why are there entire medical specialties for teeth and feet? In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us just where we inherited our achy, brilliant bodies in the process of evolution.

For more than two millennia, Istanbul has stood at the crossroads of the world, perched at the very tip of Europe, gazing across the shores of Asia. The history of this city - known as Byzantium, then Constantinople, now Istanbul - is at once glorious, outsized, and astounding. Founded by the Greeks, its location blessed it as a center for trade but also made it a target of every empire in history, from Alexander the Great and his Macedonian Empire, to the Romans and later the Ottomans.

Wondering whether eating powdered mummies might be just the thing to cure your ills? Tempted by those vintage ads suggesting you wear radioactive underpants for virility? Ever considered drilling a hole in your head to deal with those pesky headaches? Probably not. But for thousands of years, people have done things like this - and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.

Since the Gutenberg Bible first went on sale in 1455, printing has been viewed as one of the highest achievements of human innovation. But the march of progress hasn't been smooth; downright bizarre is more like it. Printer's Error chronicles some of the strangest and most humorous episodes in the history of Western printing. Take, for example, the Gutenberg Bible. While the book is regarded as the first printed work in the Western world, Gutenberg's name doesn't appear anywhere on it.

Birds are astonishingly intelligent creatures. In fact, according to revolutionary new research, some birds rival primates and even humans in their remarkable forms of intelligence. Like humans, many birds have enormous brains relative to their size. Although small, bird brains are packed with neurons that allow them to punch well above their weight.

The dome of the Santa Maria del Fiore, the great cathedral of Florence, is among the most enduring symbols of the Renaissance, an equal to the works of Leonardo and Michelangelo. Its designer was Filippo Brunelleschi, a temperamental architect and inventor who rediscovered the techniques of mathematical perspective. Yet the completion of the dome was not Brunelleschi’s glory alone. He was forced to share the commission with his archrival, the canny and gifted sculptor Lorenzo Ghiberti.

Is Italian olive oil really Italian, or are we dipping our bread in lamp oil? Why are we masochistically drawn to foods that can hurt us, like hot peppers? Far from being a classic American dish, is apple pie actually...English? Matt Siegel sets out “to uncover the hidden side of everything we put in our mouths”. Siegel also probes subjects ranging from the myths - and realities - of food as aphrodisiac, to how one of the rarest and most exotic spices in all the world (vanilla) became a synonym for uninspired sexual proclivities.

The dust storms that terrorized the High Plains in the darkest years of the Depression were like nothing ever seen before or since. Following a dozen families and their communities through the rise and fall of the region, Timothy Egan tells of their desperate attempts to carry on through blinding black dust blizzards, crop failure, and the death of loved ones. Brilliantly capturing the terrifying drama of catastrophe, he does equal justice to the human characters who become his heroes.

Montana 1925: Three brave kids from New York board the orphan train headed west. An Irish boy who lost his whole family to Spanish flu, a tiny girl who won’t talk, and a volatile young man who desperately needs to escape Hell’s Kitchen. They are paraded on platforms across the Midwest to work-worn folks and journey countless miles, racing the sun westward. Before they reach the last rejection and stop, the kids come up with a daring plan, and they set off toward the Yellowstone River and grassy mountains where the wild horses roam.

In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

Montgomery, Alabama, 1973. Fresh out of nursing school, Civil Townsend intends to make a difference, especially in her African American community. At the Montgomery Family Planning Clinic, she hopes to help women shape their destinies, to make their own choices for their lives and bodies.

According to Confucius, “an educated woman is a worthless woman,” but Tan Yunxian—born into an elite family, yet haunted by death, separations, and loneliness—is being raised by her grandparents to be of use. Her grandmother is one of only a handful of female doctors in China, and she teaches Yunxian the pillars of Chinese medicine, the Four Examinations—looking, listening, touching, and asking—something a man can never do with a female patient.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

1860: As the clash between the states rolls slowly to a boil, Elizabeth Packard, housewife and mother of six, is facing her own battle. The enemy sits across the table and sleeps in the next room. Her husband of 21 years is plotting against her because he feels increasingly threatened - by Elizabeth’s intellect, independence, and unwillingness to stifle her own thoughts. So Theophilus makes a plan to put his wife back in her place. One summer morning, he has her committed to an insane asylum.

Hillary Rodham Clinton and her daughter, Chelsea, share the stories of the gutsy women who have inspired them - women with the courage to stand up to the status quo, ask hard questions, and get the job done.

We know it simply as "the pill", yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

In The Butchering Art, the historian Lindsey Fitzharris reveals the shocking world of 19th-century surgery on the eve of profound transformation. She conjures up early operating theaters - no place for the squeamish - and surgeons, working before anesthesia, who were lauded for their speed and brute strength. They were baffled by the persistent infections that kept mortality rates stubbornly high. A young, melancholy Quaker surgeon named Joseph Lister would solve the deadly riddle and change the course of history.

There’s a quiet revolution happening in the way we die. More than 1.5 million Americans a year die in hospice care - nearly 44 percent of all deaths - and a vast industry has sprung up to meet the growing demand. Once viewed as a New Age indulgence, hospice is now a $14 billion business and one of the most successful segments in health care. Changing the Way We Die, by award-winning journalists Fran Smith and Sheila Himmel, is the first book to take a broad, penetrating look at the hospice landscape.

Rosalind Franklin was what can only be called an overlooked genius. Although she was not fully credited for the feat at the time, her work led to major breakthroughs in our understanding of DNA. In fact, she took the first X-ray photo of DNA in all of its double helix glory. By the time her former colleagues were being showered with accolades for results they made at least partially based on her findings, Franklin would not be around to see it. Sadly, it’s believed that her use of X-ray equipment gave her terminal cancer, cutting her life short at age 37.

Leaving a life marked by crippling setbacks and his father's doubt, in 1967 a 20-something doctor from India arrived in America with only five dollars and the desire to claim his American dream. Faced with an entirely new culture, racism, and the lasting effects of disabling childhood injuries, through hard work and perseverance he overcame all odds. Now having performed over 15,000 open-heart surgeries, more than nearly every surgeon in history, Dr. Singh reflects on his most memorable patients and his incredible personal life.

By the time he was 30, Dr. Benjamin Rush had signed the Declaration of Independence, edited Common Sense, toured Europe as Benjamin Franklin’s protégé, and become John Adams’s confidant, and was soon to be appointed Washington’s surgeon general. And as with the greatest Revolutionary minds, Rush was only just beginning his role in 1776 in the American experiment.

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

Teeth takes listeners on a disturbing journey into America's silent epidemic of oral disease, exposing the hidden connections between tooth decay and stunted job prospects, low educational achievement, social mobility, and the troubling state of our public health.

When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

The Chopra brothers were among the most eager and ambitious of the new generation. In the 1970s, they each emigrated to the United States to make a new life. Both faced tough obstacles: while Deepak encountered resistance from Western-trained doctors over what he called the mind-body connection, Sanjiv struggled to reconcile the beliefs of his birthplace with those of his new home. Eventually, each brother became convinced that America was the right place to build a life, and the Chopras went on to great achievements.

Mohandas Gandhi inspired the spiritual and political souls of millions of people. His concept of nonviolent resistance propelled numerous struggles throughout the world, including the civil rights movement in America. Written after his release from prison, first published in English in 1927, My Experiments with Truth is Gandhi's autobiography, documenting his spiritual journey amidst the political strife of his times.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

1860: As the clash between the states rolls slowly to a boil, Elizabeth Packard, housewife and mother of six, is facing her own battle. The enemy sits across the table and sleeps in the next room. Her husband of 21 years is plotting against her because he feels increasingly threatened - by Elizabeth’s intellect, independence, and unwillingness to stifle her own thoughts. So Theophilus makes a plan to put his wife back in her place. One summer morning, he has her committed to an insane asylum.

In 1942, the Gestapo sent out an urgent transmission: "She is the most dangerous of all Allied spies. We must find and destroy her." The target in their sights was Virginia Hall, a Baltimore socialite who talked her way into Special Operations Executive, the spy organization dubbed Winston Churchill's "Ministry of Ungentlemanly Warfare." She became the first Allied woman deployed behind enemy lines and - despite her prosthetic leg - helped to light the flame of the French Resistance, revolutionizing secret warfare as we know it.

The Watchmaker’s Daughter is one of the greatest stories of World War II that listeners haven’t heard: the remarkable and inspiring life story of Corrie ten Boom—a groundbreaking, female Dutch watchmaker, whose family unselfishly transformed their house into a hiding place straight out of a spy novel to shelter Jews and refugees from the Nazis during Gestapo raids. Even though the Nazis knew what the ten Booms were up to, they were never able to find those sheltered within the house when they raided it.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

Now published in five languages, Strange Medicine casts a gimlet eye on the practice of medicine through the ages that highlights the most dubious ideas, bizarre treatments, and biggest blunders. From bad science and oafish behavior to stomach-turning procedures that hurt more than helped, Strange Medicine presents strange but true facts and an honor roll of doctors, scientists, and dreamers who inadvertently turned the clock of medicine backward.

In the 1930s, Germany was a hotbed of scientific thought. But after the Nazis took power, Jewish and female citizens were forced out of their academic positions. Hedwig Kohn, Lise Meitner, Hertha Sponer and Hildegard Stücklen were eminent in their fields, but they had no choice but to flee due to their Jewish ancestry or anti-Nazi sentiments. Their harrowing journey out of Germany became a life-and-death situation that required Herculean efforts of friends and other prominent scientists.

A puzzling series of dental explosions beginning in the 19th century is just one of many strange tales that have long lain undiscovered in the pages of old medical journals. Award-winning medical historian Thomas Morris delivers one of the most remarkable, cringe-inducing collections of stories ever assembled.

Elizabeth Blackwell believed from an early age that she was destined for a mission beyond the scope of "ordinary" womanhood. Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an MD. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.

Paying homage to some of the greatest women the world has ever seen, Extraordinary Women in History is a testament to the power of dedication, courage, tenacity, and never giving up. Their stories will encourage you to take action and prove that barriers only exist to be broken.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

Explore real women’s tales of health-care trauma and medical misogyny with this meticulously researched, in-depth examination of the women’s health crisis in America - and what we can do about it.

Imagine undergoing an operation without anesthesia performed by a surgeon who refuses to sterilize his tools - or even wash his hands. This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the 19th century. Although he died at just 48, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.