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Innovate and React

Innovate and React

By: Kevin Hares
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 Talking about innovations in chemistry Chemistry Science
Episodes
  • Mitochondrial Biogenesis - How mitochondria get their spare parts

    Mitochondrial Biogenesis - How mitochondria get their spare parts
    May 21 2025
    In this episode of Innovate and React we look at the interface between biology and chemistry. Alexandra, a biochemist studying mitochondrial biogenesis, shares her journey from moving to Germany, and ultimately diving into biochemistry. The conversation delves into the complex processes of mitochondrial function, including their role in energy production, calcium signaling, and apoptosis (programmed cell death). Alexandra discusses her current research on the ER SURF pathway and its implications for understanding protein transport, which could potentially lead to breakthroughs in treating diseases like cancer and Parkinson's. The episode emphasizes the interconnectedness of chemistry and biology and the importance of fundamental research in advancing scientific knowledge.
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    56 mins
  • Is doing a PhD in worth it? From Brown Sludge to Breakthroughs

    Is doing a PhD in worth it? From Brown Sludge to Breakthroughs
    Apr 15 2025
    Are you thinking about pursuing a PhD in chemistry and have wondered if its with the struggle? In this episode of 'Innovate and React', we discuss the personal and professional journey of pursuing a PhD and share our motivations for studying chemistry. We discuss the challenges and surprises encountered during our PhD journey, and the important skills we developed through teaching and research. Every journey is different and depends on many different things. We give a glimpse into our experience with doing a PhD in chemistry and how it can be worth it.
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    38 mins
  • Challenging HSAB: Reactive Molecules and Nucleophiles

    Challenging HSAB: Reactive Molecules and Nucleophiles
    Apr 1 2025
    In this episode of Innovate and React, I am talking with Justus Reitz, a chemist from TU Dortmund University, about the limitations of the HSAB (Hard and Soft Acids and Bases) concept in predicting reaction outcomes. We explore an alternative approach using the nucleophilicity scale developed by the Mayr group, which offers a more accurate prediction method. Justus shares insights from his PhD research on stabilizing highly reactive molecules, particularly the synthesis and stabilization of diazoalkenes. We discuss how the Mayr nucleophilicity scale can facilitate understanding and controlling chemical reactions, bridging the gap between theoretical concepts and practical applications. For more check out innovateandreact.com
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    44 mins
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