• Joseph Takahashi - discovery of Clock gene, circadian alignment, CR and longevity. PATC episode 19.

  • Aug 6 2024
  • Length: 1 hr and 12 mins
  • Podcast

Joseph Takahashi - discovery of Clock gene, circadian alignment, CR and longevity. PATC episode 19.

  • Summary

  • Episode 19 of the Performance Around the Clock podcast comes from the 2024 Society for Research on Biological Rhythms (SRBR) biennial meeting in San Juan, Puerto Rico. We have the honor to talk with one of the pillars of the circadian field - Dr. Joseph Takahashi. Dr. Takahashi pioneered the use of forward genetics and positional cloning in mouse as a tool to discover genes that underlie neurobiology and behavior. His discovery of clock genes led to a description of a conserved circadian clock mechanism in animals. In this podcast, we hear about how his lab discovered and cloned the mouse circadian Clock gene. In addition, we find out how circadian alignment of feeding, daily fasting and caloric restriction can combine to increase longevity.


    Dr. Takahashi has authored more than 300+ scientific publications and the recipient of many awards and distinctions including:

    The Honma Prize in Biological Rhythms Research

    NSF Presidential Young Investigator Award

    Searle Scholars Award

    Bristol-Myers Squibb Unrestricted Grant in Neuroscience, and the C. U. Ariens Kappers Medal. W. Alden Spencer Award in Neuroscience from Columbia University

    Fellow of the American Academy of Arts and Sciences

    Member of the National Academy of Sciences

    Member of the National Academy of Medicine

    Gruber Neuroscience Prize at the Society for Neuroscience


    Guest:

    Dr. Joseph Takahashi

    Chair of the Department of Neuroscience at UT Southwestern Medical Center

    Loyd B. Sands Distinguished Chair in Neuroscience

    X (formerly Twitter): @CircadianClocks

    https://twitter.com/circadianclocks

    UT Southwestern profile:

    https://profiles.utsouthwestern.edu/profile/105885/joseph-takahashi.html

    Lab webpage:

    https://labs.utsouthwestern.edu/takahashi-lab


    Host:

    Dr. Satchin Panda

    @SatchinPanda

    https://x.com/SatchinPanda

    Instagram: @satchin.panda

    https://www.instagram.com/satchin.panda/


    Links:

    Donations: https://panda.salk.edu/giving/

    Research: https://www.salk.edu/scientist/satchidananda-panda/

    More science: https://mycircadianclock.org/


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