MeSsy with Christina Applegate & Jamie-Lynn Sigler

By: Wishbone Production
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  • Summary

  • On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
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Episodes
  • Katey Sagal

    Katey Sagal
    Mar 11 2025
    This week, Christina and Jamie are joined by Katey Sagal. They share their perspectives from “Married... with Children,” and discuss walking through fear, living life one day at a time, shame, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch Shop MeSsy Merch: https://messypodcastmerch.giveswagger.com/messy_podcast_merch/shop/home This episode is sponsored by: Honeylove - Get 20% OFF @honeylove by going to honeylove.com/MESSY! #honeylovepod BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.” Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details. Public Rec - Upgrade your wardrobe instantly and save 20% off with the code MS at https://www.publicrec.com/ms #publicrecpod MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at mudwtr.com/MESSY! #mudwtrpod Fatty15 - Fatty15 is on a mission to replenish your C15 levels and restore your long-term health. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and using code MESSY at checkout.
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    1 hr and 22 mins
  • Heels and Hats

    Heels and Hats
    Mar 4 2025
    This week, Christina and Jamie read listener emails and discuss giving yourself a little push, finding ways to enjoy life, setting achievable goals, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Function: - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.” Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details. Lume - Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code MESS at LumeDeodorant.com! #lumepod iRestore - Unlock your best skin with @iRestorelaser and save $205 off your iRestore Illumina Face Mask with code Messy25 at irestorelaser.com/messy25 #irestorepod AG1 - AG1 is offering new subscribers a FREE $76 gift when you sign up. You’ll get a Welcome Kit, a bottle of D3K2 AND 5 free travel packs in your first box. So make sure to check out DrinkAG1.com/messy to get this offer!
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    1 hr and 4 mins
  • How to Make Your Own Community with Allie Signorelli

    How to Make Your Own Community with Allie Signorelli
    Feb 25 2025
    This week, Christina and Jamie are joined by Allie Signorelli, a Young Onset Parkinson’s patient and advocate. They discuss her journey to getting diagnosed, the importance of being honest, paying attention to symptoms, finding gratitude, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Mudwtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at mudwtr.com/messy #mudwtrpod Calm - Stress less, sleep more, and live better with Calm. For listeners of our show, Calm is offering an exclusive offer of 40% off a Calm Premium Subscription at calm.com/MESSY for 40% off unlimited access to Calm’s entire library. Purity Woods - The good people at Purity Woods have a special coupon code specifically for our listeners, so you can try it for yourself for 27% off today. Just go to puritywoods.com/MESSY or enter MESSY at checkout. Function - Function currently has a waitlist, but they are offering my audience the chance to skip it! Head to functionhealth.com/MESSY or enter code MESSY when signing up to skip the waitlist!” Sleep Number - Why choose a Sleep Number smart bed? So you can choose your ideal comfort on either side. The only bed that lets you make each side firmer or softer, whenever you like – your Sleep Number setting. Sleep Number smart beds start at $999. Exclusively at a Sleep Number® store near you. See store or sleepnumber.com for details.
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    1 hr and 11 mins

What listeners say about MeSsy with Christina Applegate & Jamie-Lynn Sigler

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Profile Image for Jill Simpson

So relatable and helpful!

For someone who was just diagnosed, this has been my savior! I can’t wait for every episode to come out! Nothing but love for Jamie and Christina! 🧡🧡🧡

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Profile Image for sdeedeec

It Gets Real

I have MS and I love this podcast. We shouldn't have to be ashamed of our feelings no matter how we decide to handle our disease. I'm sad, furious and devastated by this disease and almost no one gets it. These two strong badass ladies get it. If I get one more positivity lecture my head will explode. This podcast will help anyone dealing with a chronic disease. The guests are interesting as well. I literally can't wait for new episodes. Love it!

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Profile Image for Julie

The podcast and conversation I've been waiting for.

Finally voices talking about things that I've been struggling with alone. It's very empowering to hear people have conversations that are this loaded and hard to have. I feel like this is nothing less than empowering. it truly gives voices to people who have been voiceless for too long.

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Profile Image for C

Love these ladies!

These ladies keep me interested for the full podcast and it is hard at times hearing some of your fav people struggling so much. They always have a great conversations and the guests are cool.. Even Kimmel.
Love each and every episode.

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Profile Image for Stacy

No NS for MS

No holding back in this one. the mame says it all. I already learned 2 things from Christina (thank you) about this crazy disease called MS. Love it! I'm following,

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Profile Image for Raina

I'm not alone hearing you talk

I love how real this talk come across... I love how you explain how your feeling and how you relate to each other and try to help each other stay on track., my wife is always tell me to finish why I am saying too so I dont lose track... by the time she's done saying that...I have already forgotten too so when y'all say that.. I'm like oh God that you.. that's me. I love this so much... for at least once a week. I'm totally understood and dont feel so alone in it. thank you for being so open and aharing your stories.

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Profile Image for April D

The "Real"ing is Feel!

I have found so much peace and comradery listening to you ladies! You say it like it is. You share it how you feel it. After 21 years with this disease, it is so nice to hear the it's not just me....my experiences and how I process them are not "crazy". I am that Type A personality who is always "fine" and feeling "great" and never want to burden others with my truth. It has been so great to listen to you both allowing each other to be who you are and have all the real feelings that come along with having MS. Thank you for sharing your truths. I appreciate you both.

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Profile Image for Stephanie Dennis

Just what us fellow MSers need

Omg thank you !! This is amazing for
us that what the raw and real emotions with this evil disease- even the humor that people don’t get !!!! My new favorite podcast !!

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Profile Image for Gracie

Raw & Honest

Love that Jamie & Christina are being raw and honest. I pray that Christina feels better soon. Her pain is audible. Jamie's perspective, comes with years of navigating the disease. Wishing these two great humans the best and a successful podcast. I will be listening.

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Profile Image for Abigail T.

MS SUCKS-and these ladies help me through it!

I can't remember how I found this podcast, but I'm LOVING it! I have MS, and I was likely looking up Christina Applegate, to see if I could find her talking about it. Cut to, finding this hilariously, inspiring

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