Drs Trisha Suppes and Scott T. Aaronson discuss rapid-acting therapies for bipolar disorder and the future of psychedelics and neuromodulation in its treatment.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999802. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Bipolar Disorder https://emedicine.medscape.com/article/286342-overview

The Effects of Vagus Nerve Stimulation on the Course and Outcomes of Patients With Bipolar Disorder in a Treatment-Resistant Depressive Episode: A 5-Year Prospective Registry https://pubmed.ncbi.nlm.nih.gov/32358769/

A 5-Year Observational Study of Patients With Treatment-Resistant Depression Treated With Vagus Nerve Stimulation or Treatment as Usual: Comparison of Response, Remission, and Suicidality https://pubmed.ncbi.nlm.nih.gov/28359201/

c-Fos and pERK, Which Is a Better Marker for Neuronal Activation and Central Sensitization After Noxious Stimulation and Tissue Injury? https://pubmed.ncbi.nlm.nih.gov/19898681/

Repetitive Transcranial Magnetic Stimulation in the Treatment of Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/33282175/

Efficacy of Active vs Sham Intermittent Theta Burst Transcranial Magnetic Stimulation for Patients With Bipolar Depression: A Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/33710288/

A Retrospective Analysis of Bipolar Depression Treated With Transcranial Magnetic Stimulation https://pubmed.ncbi.nlm.nih.gov/33169946/

When to Hold and When to Fold: Early Prediction of Nonresponse to Transcranial Magnetic Stimulation in Major Depressive Disorder https://pubmed.ncbi.nlm.nih.gov/38458381/

Dosing Transcranial Magnetic Stimulation in Major Depressive Disorder: Relations Between Number of Treatment Sessions and Effectiveness in a Large Patient Registry https://pubmed.ncbi.nlm.nih.gov/37827360/

Sequenced Treatment Alternatives to Relieve Depression (STAR*D): Rationale and Design https://pubmed.ncbi.nlm.nih.gov/15061154/

Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes: A Nonrandomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/38055270/

Drs Trisha Suppes and Michael J. Ostacher discuss treatments for patients with bipolar disorder who also have substance abuse disorder.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999801. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Bipolar Disorder https://emedicine.medscape.com/article/286342-overview

Management of Comorbid Bipolar Disorder and Substance Use Disorders https://pubmed.ncbi.nlm.nih.gov/28301219/

Drs Trisha Suppes and Holly A. Swartz discuss the impact of circadian and social rhythms on patients with bipolar disorder, as well as the power of psychotherapy.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/999800. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Bipolar Disorder https://emedicine.medscape.com/article/286342-overview

Circadian Rhythm in Bipolar Disorder: A Review of the Literature https://pubmed.ncbi.nlm.nih.gov/29869403/

Efficacy of the Interpersonal and Social Rhythm Therapy (IPSRT) in Patients With Bipolar Disorder: Results From a Real-World, Controlled Trial https://pubmed.ncbi.nlm.nih.gov/32165907/

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 Guidelines for the Management of Patients With Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/29536616/

Psychotherapy Alone and Combined With Medication as Treatments for Bipolar II Depression: A Randomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/28703949/

26th Annual Conference of the International Society for Bipolar Disorders September 29 – October 1, 2024 Reykjavik, Iceland https://www.isbd.org/Program

Nutrition and Bipolar Disorder: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/35608150/

Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes: A Nonrandomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/38055270/

Brain Stimulation Treatment for Bipolar Disorder https://pubmed.ncbi.nlm.nih.gov/36515461/