In clinic, treating patients for IBS is only one piece of the puzzle. Overlapping disorders are common in IBS. Drs Lin Chang and Magnus Simrén discuss the nuances of this condition.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/987263). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Irritable Bowel Syndrome (IBS) https://emedicine.medscape.com/article/180389-overview

Gastroesophageal Reflux Disease https://emedicine.medscape.com/article/176595-overview

Approach to Disorders of Gut-Brain Interaction https://pubmed.ncbi.nlm.nih.gov/36868754/

Inflammatory Bowel Disease https://emedicine.medscape.com/article/179037-overview

Prevalence of Irritable Bowel Syndrome-Like Symptoms Using Rome IV Criteria in Patients With Inactive Inflammatory Bowel Disease and Relation With Quality of Life https://pubmed.ncbi.nlm.nih.gov/32384473/

Celiac Disease (sprue) https://emedicine.medscape.com/article/171805-overview

Prevalence of Irritable Bowel Syndrome-Type Symptoms in Patients With Celiac Disease: A Meta-analysis https://pubmed.ncbi.nlm.nih.gov/23246645/

Gastroesophageal Reflux Disease, Functional Dyspepsia and Irritable Bowel Syndrome: Common Overlapping Gastrointestinal Disorders https://pubmed.ncbi.nlm.nih.gov/30386113/

Rome IV Criteria https://theromefoundation.org/rome-iv/rome-iv-criteria/

Neuromodulators in the Brain-Gut Axis: Their Role in the Therapy of the Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/34812436/

Cognitive Behavioral Therapy for IBS and Other FGIDs https://iffgd.org/resources/publication-library/cognitive-behavioral-therapy-for-ibs-and-other-fgids/

Proton Pump Inhibitors (PPI) https://www.ncbi.nlm.nih.gov/books/NBK557385/

Central Sensitization and Severity of Gastrointestinal Symptoms in Irritable Bowel Syndrome, Chronic Pain Syndromes, and Inflammatory Bowel Disease https://pubmed.ncbi.nlm.nih.gov/33860970/

A Distinctive Profile of Family Genetic Risk Scores in a Swedish National Sample of Cases of Fibromyalgia, Irritable Bowel Syndrome, and Chronic Fatigue Syndrome Compared to Rheumatoid Arthritis and Major Depression https://pubmed.ncbi.nlm.nih.gov/35354508/

Mood and Anxiety Disorders in Chronic Fatigue Syndrome, Fibromyalgia, and Irritable Bowel Syndrome: Results From the Lifelines Cohort Study https://pubmed.ncbi.nlm.nih.gov/25768845/

Defining Optimal Care for Functional Gut Disorders - Multi-Disciplinary Versus Standard Care: A Randomized Controlled Trial Protocol https://pubmed.ncbi.nlm.nih.gov/31437539/

Can brain-gut behavioral therapies reduce IBS symptoms, not just mood and psychological symptoms? Drs Lin Chang and Laurie Keefer discuss why incorporating this therapy in your practice works.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/987262). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Irritable Bowel Syndrome (IBS) https://emedicine.medscape.com/article/180389-overview

Benson-Henry Institute for Mind Body Medicine https://bensonhenryinstitute.org/mission-history/

Microbiome https://www.genome.gov/genetics-glossary/Microbiome

Vagus Nerve as Modulator of the Brain-Gut Axis in Psychiatric and Inflammatory Disorders https://pubmed.ncbi.nlm.nih.gov/29593576/

Burden of Anxiety and Depression Among Hospitalized Patients With Irritable Bowel Syndrome: A Nationwide Analysis https://pubmed.ncbi.nlm.nih.gov/36593438/

A Rome Working Team Report on Brain-Gut Behavior Therapies for Disorders of Gut-Brain Interaction https://pubmed.ncbi.nlm.nih.gov/34529986/

Cognitive-Behavioral Therapy for IBS and Other FGIDs https://iffgd.org/resources/publication-library/cognitive-behavioral-therapy-for-ibs-and-other-fgids/

App-Delivered Gut-Directed Hypnotherapy Program Nerva Improves Symptoms in Patients With Irritable Bowel Syndrome but How Can We Ensure Users Are Compliant? https://gi.org/media/press-info-scientific-meeting/featured-science/oral-15

The Role of Resilience in Irritable Bowel Syndrome, Other Chronic Gastrointestinal Conditions, and the General Population https://pubmed.ncbi.nlm.nih.gov/32835842/

How do you help patients with soft stool that won't move through manage idiopathic constipation? Join Drs Lin Chang and Anthony Lembo as they discuss nuanced decision-making around treating IBS subtypes.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/987261). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Irritable Bowel Syndrome (IBS) https://emedicine.medscape.com/article/180389-overview

Sigmoid Afferent Mechanisms in Patients With Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/9201070/

Peripheral Opioids for Functional GI Disease: A Reappraisal https://pubmed.ncbi.nlm.nih.gov/16699267/

Dietary Concerns and Patient-Focused Care in Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/36398143/

The Epidemiology of Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/24523597/

Diagnosis and Treatment of Irritable Bowel Syndrome: A Review https://pubmed.ncbi.nlm.nih.gov/33651094/

Review Article: An Integrated Approach to the Irritable Bowel Syndrome https://pubmed.ncbi.nlm.nih.gov/10429736/

AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea https://pubmed.ncbi.nlm.nih.gov/35738725/

Psyllium Reduces Inulin-Induced Colonic Gas Production in IBS: MRI and in Vitro Fermentation Studies https://pubmed.ncbi.nlm.nih.gov/34353864/

Efficacy of Secretagogues in Patients With Irritable Bowel Syndrome With Constipation: Systematic Review and Network Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/30144426/