Mind & Matter

By: Nick Jikomes
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  • Summary

  • Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it.

    The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today.


    Not medical advice.

    At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it.


    As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet.


    I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint.


    My beliefs:

    • Taking ownership of your health starts with taking ownership of your information diet.
    • All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.
    • Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information.


    Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi:

    • “Γνῶθι σεαυτόν” (Know thyself)
    • “Μηδὲν ἄγαν” (Nothing in excess)
    • “Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)
    © 2024 Nick Jikomes
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Episodes
  • Vaccine Contamination & Fiat Science | Kevin McKernan | IS #5

    Vaccine Contamination & Fiat Science | Kevin McKernan | IS #5
    Nov 21 2024

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    About the guest: Kevin McKernan is the founder and Chief Science Officer of Medicinal Genomics. He has worked in biotechnology since the early 1990s, when he was involved in the Human Genome Project.

    Episode summary: Nick and Kevin discuss: components of the COVID vaccines, including modified mRNA & lipid nanoparticles; DNA contamination in COVID vaccines; vaccine adverse events & IgG4 immune modulation; concerns with COVID PCR testing; origins of the SARS-CoV-2 virus; Fiat Science from the AIDS epidemic to today; how Big Pharma works with government regulators; decentralized medicine; and more.

    Related episodes:

    • M&M #149: DNA & RNA Biology, mRNA Vaccines, Vax Contamination & Side Effects, Spike Protein, Ivermectin, Hop Latent Viroid | Kevin McKernan
    • M&M #97: How Did the SARS-CoV-2 Virus Originate? | Alex Washburne

    Special offer: Use code MINDMATTERSPECIAL for a limited time to get a free 1-year premium subscription to Consensus, a new AI-powered research tool to help you find the best science, faster.

    *This content is never meant to serve as medical advice

    Support the show

    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

    Affiliates:

    • MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off.
    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

    Learn all the ways you can support my efforts


    ...
    Show more Show less
    41 mins
  • Skin Biology: Hormones, Light, Vitamin D, Melatonin & Stress | Andrzej Slominski | #189

    Skin Biology: Hormones, Light, Vitamin D, Melatonin & Stress | Andrzej Slominski | #189
    Nov 18 2024

    Send us a text

    About the guest: Andrzej Slominski, MD, PhD is a dermapathologist and skin biologist who has spent decades studying skin biology, especially regarding endocrinology (hormones), stress response, photobiology, and more.

    Episode summary: Nick and Dr. Slominski discuss: hormone production in the skin; vitamin D photobiology; risks and benefits of UVB light; skin cancer & sunscreen; protective effects of melatonin production in the skin; and more.

    Related episodes:

    • M&M #104: Benefits & Risks of UV Radiation & Sunlight, Skin Health, Vitamin D, Nitric Oxide, Evolution of Skin Color | Richard Weller
    • M&M #146: Photobiology, Sunlight, Firelight, Incandescent Bulbs vs. LEDs, Mitochondria, Melatonin, Sunscreen & the Optics of the Body | Scott Zimmerman

    *This content is never meant to serve as medical advice

    Support the show

    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

    Affiliates:

    • MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off.
    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

    Learn all the ways you can support my efforts


    ...
    Show more Show less
    1 hr and 3 mins
  • Psychedelics, Functional Neuroimaging & the Human Brain | Joshua Siegel | #188

    Psychedelics, Functional Neuroimaging & the Human Brain | Joshua Siegel | #188
    Nov 13 2024

    Send us a text

    About the guest: Joshua Siegel, MD, PhD is a psychiatrist & systems neuroscience at New York University. He uses functional imaging to study the effects of psychedelics and other drugs on the human brain.

    Episode summary: Nick and Dr. Siegel discuss: fMRI and how it works; relationship between neural activity and blood flow; functional connectivity & the default mode network of the human brain; the functional effects of psilocybin on the brain; the role that subjective & expectancy effects in psychedelics medicine; and more.

    Related episodes:

    • M&M #173: Psychedelics, Consciousness, Psychiatry, Psychology, Mental Health & the Entropic Brain Hypothesis
    • M&M #163: Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics

    *This content is never meant to serve as medical advice

    Support the show

    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

    Affiliates:

    • MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off.
    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

    Learn all the ways you can support my efforts


    ...
    Show more Show less
    1 hr and 12 mins

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