• Vaccine Contamination & Fiat Science | Kevin McKernan | IS #5
    Nov 21 2024

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    About the guest: Kevin McKernan is the founder and Chief Science Officer of Medicinal Genomics. He has worked in biotechnology since the early 1990s, when he was involved in the Human Genome Project.

    Episode summary: Nick and Kevin discuss: components of the COVID vaccines, including modified mRNA & lipid nanoparticles; DNA contamination in COVID vaccines; vaccine adverse events & IgG4 immune modulation; concerns with COVID PCR testing; origins of the SARS-CoV-2 virus; Fiat Science from the AIDS epidemic to today; how Big Pharma works with government regulators; decentralized medicine; and more.

    Related episodes:

    • M&M #149: DNA & RNA Biology, mRNA Vaccines, Vax Contamination & Side Effects, Spike Protein, Ivermectin, Hop Latent Viroid | Kevin McKernan
    • M&M #97: How Did the SARS-CoV-2 Virus Originate? | Alex Washburne

    Special offer: Use code MINDMATTERSPECIAL for a limited time to get a free 1-year premium subscription to Consensus, a new AI-powered research tool to help you find the best science, faster.

    *This content is never meant to serve as medical advice

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    41 mins
  • Skin Biology: Hormones, Light, Vitamin D, Melatonin & Stress | Andrzej Slominski | #189
    Nov 18 2024

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    About the guest: Andrzej Slominski, MD, PhD is a dermapathologist and skin biologist who has spent decades studying skin biology, especially regarding endocrinology (hormones), stress response, photobiology, and more.

    Episode summary: Nick and Dr. Slominski discuss: hormone production in the skin; vitamin D photobiology; risks and benefits of UVB light; skin cancer & sunscreen; protective effects of melatonin production in the skin; and more.

    Related episodes:

    • M&M #104: Benefits & Risks of UV Radiation & Sunlight, Skin Health, Vitamin D, Nitric Oxide, Evolution of Skin Color | Richard Weller
    • M&M #146: Photobiology, Sunlight, Firelight, Incandescent Bulbs vs. LEDs, Mitochondria, Melatonin, Sunscreen & the Optics of the Body | Scott Zimmerman

    *This content is never meant to serve as medical advice

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    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
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    1 hr and 3 mins
  • Psychedelics, Functional Neuroimaging & the Human Brain | Joshua Siegel | #188
    Nov 13 2024

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    About the guest: Joshua Siegel, MD, PhD is a psychiatrist & systems neuroscience at New York University. He uses functional imaging to study the effects of psychedelics and other drugs on the human brain.

    Episode summary: Nick and Dr. Siegel discuss: fMRI and how it works; relationship between neural activity and blood flow; functional connectivity & the default mode network of the human brain; the functional effects of psilocybin on the brain; the role that subjective & expectancy effects in psychedelics medicine; and more.

    Related episodes:

    • M&M #173: Psychedelics, Consciousness, Psychiatry, Psychology, Mental Health & the Entropic Brain Hypothesis
    • M&M #163: Anesthesia, Placebo Effects, Consciousness, Subjectivity, MDMA, Ketamine, Opioids, Psychedelics

    *This content is never meant to serve as medical advice

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    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
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    1 hr and 12 mins
  • Synesthesia & Effects of Digital Technology on Brain & Mental Health | Richard Cytowic | #187
    Nov 10 2024

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    About the guest: Richard Cytowic is a neurologist, poplar science writer and professor at the George Washington University.

    Episode summary: Nick and Dr. Cytowic discuss: the effects of smart phones and social media on the developing and adult brain; artificial blue light vs. broad spectrum natural light; attention & addiction to technology; sensory overstimulation & “virtual autism”; synesthesia and multimodal sensory perception; and more.

    Related episodes:

    • M&M 78: Nature vs. Nurture, Neurogenetics, Personality, Autism, Schizophrenia, Synesthesia, Perception, Agency & Free Will | Kevin Mitchell

    *This content is never meant to serve as medical advice

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    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

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    1 hr and 9 mins
  • Kidney Biology: Simple Diet & Lifestyle Practices for Kidney Health | Thomas Weimbs | #186
    Nov 6 2024

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    About the guest: Thomas Weimbs, PhD is a biologist at UC-Santa Barbara whose lab studies kidney function in health and disease.

    Episode summary: Nick and Dr. Weimbs discuss: basic kidney biology; kidney stones and their causes, including dietary oxalates and fructose; the kidney damaging effects of common pharmaceuticals like Ibuprofen; the beneficial effects of BHB and ketosis for kidney health; the myth that high protein intake is bad for the kidney; kidney diseases and their causes; and more.

    Full version available on Substack and YouTube.

    Related episodes:

    • M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino
    • M&M #139: Metabolic Switching, Fasting, Ketosis, Neuroplasticity, Diet & Neurodegenerative Disease | Mark Mattson

    *This content is never meant to serve as medical advice

    Support the show

    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

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    • MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off.
    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

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    1 hr and 9 mins
  • Self-Experimentation (n=1) in Metabolic Health, Lipid-Energy, Trust in Medical & Scientific Institutions | Nick Norwitz | IS#4
    Oct 31 2024

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    Full version available on Substack and YouTube.

    About the guest: Nick Norwitz, PhD received his PhD in Physiology at Oxford University and is finishing his MD degree at Harvard Medical School. He is also an independent content creator focused on making metabolic health mainstream.

    Episode summary: Nick and Dr. Norwitz discuss: blood lipids & cholesterol; high cholesterol levels and what they can mean for different people; the “lean mass hyper-responder” phenotype to carb restriction; ketogenic & carnivore diets; public trust in medical & science institutions; n=1 (“n of one”) science experiments; and more.

    Related episodes:

    • M&M 158: Ketosis & Ketogenic Diet: Brain & Mental Health, Metabolism, Diet & Exercise, Cancer, Diabetes | Dominic D'Agostino
    • IS #1: Seed Oils, Chronic Disease, Diet & Religious Cults, Mainstream Medicine vs. Independent Research | Tucker Goodrich

    *This content is never meant to serve as medical advice

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    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

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    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

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    54 mins
  • Sugar & Sweeteners: Are They Really Addictive or Unhealthy? | Nicole Avena | #185
    Oct 30 2024

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    Full version available on Substack and YouTube.

    About the guest: Nicole Avena, PhD is a neuroscientist at Mount Sinai. She studies the effects of sugar and diet on animal behavior and the brain. She is also the author of, “Sugarless.”

    Episode summary: Nick and Dr. Avena discuss: drug addiction vs. food addiction; glucose, fructose & artificial sweeteners; the extent to which sugar consumption can drive dependency & withdrawal; fructose metabolism & live health; sweetness & palatability; ultra-processed foods; and more.

    Related episodes:

    • M&M 140: Obesogens, Oxidative Stress, Dietary Sugars & Fats, Statins, Diabetes & the True Causes of Metabolic Dysfunction & Chronic Disease | Robert Lustig
    • M&M #134: Omega-6-9 Fats, Vegetable & Seed Oils, Sugar, Processed Food, Metabolic Health & Dietary Origins of Chronic Inflammatory Disease | Artemis Simopoulos | #134

    *This content is never meant to serve as medical advice

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    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

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    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

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    1 hr and 4 mins
  • Endocrine Disruptors & Metabolism: Microplastics, BPA, Estrogen, Insulin, Pancreas Biology & Metabolic Dysfunction | Angel Nadal | #184
    Oct 27 2024

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    About the guest: Angel Nadal, PhD is a biologist in Spain whose lab studies endocrine disruptors (e.g. microplastics), hormones (estrogen, insulin), and the endocrine functions of the pancreas in health & disease.

    Episode summary: Nick and Dr. Nadal discuss: endocrine biology of the pancreas; insulin and estrogen signaling in the pancreas; BPA, microplastics, and other xenoestrogens; pregnancy & fetal development; effects of hormone disruptors in males vs. females; and more.

    Related episodes:

    • M&M 145: Epigenetics, Hormones, Endocrine Disruptors, Microplastics, Xenoestrogens, Obesogens & Obesity, Inheritance of Acquired Characteristics | Bruce Blumberg
    • M&M #124: Hormonal Contraception, Sex Hormones, Menstruation, Pregnancy, Puberty, Estrogens, Androgens, Effects of Birth Control on Cognition | Adriene Beltz

    *This content is never meant to serve as medical advice.

    Support the show

    All episodes (audio & video), show notes, transcripts, and more at the M&M Substack

    Affiliates:

    • MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off.
    • SiPhox Health—Affordable, at-home bloodwork. Comprehensive set of key health markers. Use code TRIKOMES for a 10% discount.
    • Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off.
    • Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase.
    • Consensus: AI-powered academic research tool. Find & understand the best science, faster. Free 1-year premium sub with code MINDMATTERSPECIAL (expires 12.10.24)

    Learn all the ways you can support my efforts


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    1 hr and 7 mins