• TWiV 1152: Clinical update with Dr. Daniel Griffin

  • Sep 28 2024
  • Length: 58 mins
  • Podcast

TWiV 1152: Clinical update with Dr. Daniel Griffin

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  • Summary

  • In his weekly clinical update, Dr. Griffin deep dives into the durability of the antibody response following mpox vaccination, vaccine security, global mpox circulation, the origins of SARS-CoV-2, including a list TWiV episodes and combatting scientific misinformation, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if remdesivir + dexamethasone lowers mortality of hospitalized COVID-19 patients and the finding of how SARS-CoV-2 infection impacts memory and cognition. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Waning vaccine protection against mpox…..isn’t this the way the humoral immune response works? (CIDRAP) 1:46Uncontrollable mpox outbreak in Africa (Reuters) 4:10Antibodies elicited by the Jynneos vaccine against mpox contract after 6-9 months….can you believe? (medrxiv) 4:45Mpox vaccine for adolescents approved (Pharmaceutical Technology) 14:05 Clade 1b mpox visiting India (CIDRAP) 15:05 Mpox clade 1b in Kerala (ANI South Asia’s Leading Multimedia News Agency) 15:13US government orders $63M worth of small pox/mpox vaccine (Reuters) 15:34Mpox donations boosting global supply (US Department of Health and Human Services)1 million mpox vaccine doses for Africa….with love from US government (CIDRAP) 15:55 Speed doses of mpox vaccine (CIDRAP)Mpox vaccine donations (UNICEF) 17:35 Bavarian Nordic mpox vaccine (Yahoo finances)Early epicenter of COVID-19 pandemic Huanan seafood market (Science) 23:07Wildlife trade likely source of SARS-CoV-2 (Science) 23:16Zoonotic origins of SARS-CoV-2 (Science) 23:20Surveillance at the Huanan Seafood market (Europe PMC) 25:03TWiV shout outs…..all for the SARS-CoV-2 spill over from nature 25:31 TWiV 1019: Eddie Holmes on SARS-CoV-2 originsTWiV 1017: From Nature, not a labTWiV 995: Viral origin storiesTWiV 940: Eddie Holmes in on viral originsTWiV 876: Spillover market with Michael WorobeyTWiV 762: SARS-CoV-2 origins with Robert GarryTWiV 760: SARS-CoV-2 origins with Peter Daszak, Thea Kølsen Fischer, Marion KoopmansTWiV 774: Kristian Andersen, Robert Garry, and the deleted SARS-CoV-2 sequences Genetic tracking of market wildlife and viruses at Huanan Market (Cell) 18:56Combatting scientific misinformation (microbeTV: TWiV) 34:14COVID-19 deaths (CDC) 35:20COVID-19 national and regional trends (CDC)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)Suggestion for the use of a new preventive COVID-19 agent (IDSA) IDSA Guidelines on the Treatment and Management of Patients with COVID-19 (IDSA)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH) Infectious Disease Society guidelines for treatment and management (ID Society)Drug interaction checker (University of Liverpool)Molnupiravir outcomes 3 and 6 months after treatment (LANCET Infectious Diseases)Antivirals and post-COVID-19 conditions (LANCET Infectious Disease)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)Managing healthcare staffing shortages (CDC)Steroids, dexamethasone at the right time (OFID) Anticoagulation guidelines (hematology.org)Lower mortality risk associated with remdesivir + dexamethasone versus dexamethasone for hospitalized COVID-19 patients (CID) 39:17Changes in memory and cognition during the SARS-CoV-2 human challenge study (eClinical Medicine) 42:25Letters read on TWiV 1152 48:18Dr. Griffin's COVID treatment summary (pdf)Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv
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