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The Metabolism, Muscles, and Mindset Podcast

The Metabolism, Muscles, and Mindset Podcast

By: Ali Novitsky MD
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 Welcome to "The Muscles & Mindset Podcast", with your host Dr. Ali Novitsky, an acclaimed obesity medicine expert, renowned for her unique expertise in muscle optimization through exercise, nutrition, and mindset work. Her revolutionary approach to health and wellness. Dr. Novitsky is not just an expert; she is a catalyst, propelling individuals on their journey of transformation, fostering strength, endurance, and resilience, and reshaping the landscape of obesity medicine. The Muscles & Mindset Podcast aims to foster not just knowledge, but action. We'll unravel the secrets to optimizing muscle development, adhering to a nourishing diet, and cultivating a resilient mindset - three crucial pillars of a healthy and fulfilling lifestyle. But more than that, we'll provide you with actionable strategies, practical tips, and effective tools that you can seamlessly incorporate into your daily routines. This podcast isn't just about understanding the muscles and mindset, it's about turning that understanding into positive, transformative action. Get ready to embark on a journey of self-discovery and self-improvement, as you tune in to the Muscles & Mindset Podcast. Together, we'll navigate the path of health and wellness, one episode at a time. Dr. Ali Novitsky's work can be found at https://thefitcollective.com.248601 Hygiene & Healthy Living
Episodes
  • 264: The Hunger Genes - MC4R, ANKK1, Satiety, and Fasting

    264: The Hunger Genes - MC4R, ANKK1, Satiety, and Fasting
    May 28 2025
    The FIT Collective Genetic Insights Series – Episode 2Unlock the Secrets of Your Hunger Genetics and Eating Habits In this fascinating episode, Dr. Ali Novitsky, Obesity Medicine Expert and Fitness Guru, explores the powerful role genetics play in shaping our appetite, eating behaviors, and how we experience fullness (satiety). Drawing from science and personal experience, she breaks down how certain genes influence appetite, body composition, and emotional eating — and how understanding your genetic blueprint can empower you to make personalized, sustainable health choices.👩‍👧 Personal Touches & Real-Life InsightsDr. Novitsky opens with a heartwarming update about her daughter’s upcoming birthday and their summer beach plans, before diving into how her own childhood eating patterns reflect her genetic makeup.🧬 The Genetic Blueprint of EatingThe role of somatotypes (ectomorph, mesomorph, endomorph) in body composition and tendencies toward weight gain or leannessUnderstanding the genetically predetermined “set point” for weightPersonal examples comparing her own adolescent stats with her daughter’s🧠 Satiety and the MC4R GeneDeep dive into the MC4R gene, a key regulator of satietyHow MC4R variants can affect appetite control and lead to overeatingA personal story from Olive Garden highlights how genetic predispositions show up in real life🧪 Emotional Eating & the ANKK1 GeneIntroduction to the ANKK1 gene, which affects dopamine response and can drive emotional eatingThe compounding effects of having multiple genetic variants (like MC4R + ANKK1)🍽️ Practical Strategies to Support SatietyProtein-first approach when dining outHigh-protein snacks in the evening to prevent overeatingFocus on fiber and hydration to improve satietySmart use of supplements: omega-3s, vitamin D, fiber, and magnesiumTips for volume eating and managing cravings based on texture⏰ Fasting and Your GenesHow some individuals are genetically wired to skip breakfastDr. Novitsky shares her personal take on fasting and why it works for herYour genetics can play a major role in how you feel hunger, how your body responds to food, and your susceptibility to emotional eating. The more you understand your unique genetic makeup, the more effectively you can design a lifestyle that supports your optimal health — without frustration or blame.Dr. Novitsky is now enrolling participants in her Genetics Program – a unique opportunity to:✅ Get a genetics testing kit✅ Receive tailored supplement recommendations✅ Build a comprehensive health plan based on your DNA🔗 Enroll now at thefitcollective.com/genetics🕒 Timestamps:00:00 – Personal Updates & Intro03:22 – MC4R Gene & Satiety10:07 – Satiety Strategies18:08 – Eating Out Tips22:00 – Supplements That Help27:01 – Fasting & Genetics30:13 – Wrapping Up + Program Info🎧 Tune in to uncover how your genes might be guiding your hunger, food choices, and even your success in creating lasting healthy habits.🎯 Ready to Personalize Your Health?Work with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠⁠⁠⁠⁠⁠Enroll TODAY⁠⁠⁠⁠⁠⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠⁠⁠⁠⁠⁠Enroll HERE⁠⁠⁠⁠⁠⁠⁠• The Fit Collective® x InBody USA/Canada – Get 15% off select models. ⁠⁠⁠⁠⁠⁠⁠Click HERE⁠
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    32 mins
  • 263: DNA-Informed Health and Fitness Strategies - Genetic Insights

    263: DNA-Informed Health and Fitness Strategies - Genetic Insights
    May 21 2025
    The FIT Collective Genetic Insights Series – Episode 1Understanding Genetics, Stress, & Weight with Dr. Ali NovitskyDr. Ali Novitsky, board-certified in obesity medicine, kicks off a new series on how genetics influence health—especially stress responses and weight regulation. She opens with a personal story: during college, despite eating well and exercising, she gained 20 pounds in three months. Genetic testing later revealed a variant in her cortisol receptor gene, causing her body to release excess cortisol under stress—leading to high blood sugar, insulin resistance, and ultimately, weight gain.Cortisol plays a central role in stress response and metabolism. While helpful in short bursts, chronic elevation from ongoing stress can disrupt insulin function, making weight loss more difficult for those with specific genetic variants. For Dr. Novitsky, managing stress—not restricting calories or increasing workouts—was the key to reversing her weight gain.About 30% of people carry this cortisol receptor variant. In her 2022 genetics cohort, 80% tested positive. This highlights the power of personalized health strategies rooted in understanding one’s unique genetic makeup.Dr. Novitsky uses Genomind’s Mental Health Map, a genetic test offering insight into stress, mood, and focus. One critical gene it reports on is COMT, which affects dopamine breakdown. Individuals with the MetMet variant retain more dopamine—great for focus, but often sensitive to stress. Those with ValVal clear dopamine quickly, leading to impulsivity and a higher likelihood of ADHD.Another important factor is BDNF (brain-derived neurotrophic factor), a gene linked to memory, cognition, and mood. Those with a BDNF variant often need regular exercise to optimize brain health and emotional balance.The takeaway? Health isn’t one-size-fits-all. For some, gentle exercise, high-quality sleep, and stress reduction may be far more effective than intense workouts or calorie restriction. Dr. Novitsky’s approach integrates genetic awareness into actionable wellness strategies.She also introduces her four-week genetics program, which includes one-time testing, personalized supplement recommendations, and coaching based on individual results. Participants receive a lifelong health blueprint.Future episodes will explore the genetics of eating behaviors, including cravings and satiety. Listeners are encouraged to tune in and learn how DNA influences decisions, habits, and long-term health.Timestamps00:00:00 - Introduction and Personal Story00:01:00 - Understanding Cortisol and Stress00:04:00 - Genetic Testing Insights00:05:30 - Cortisol and Weight Management00:08:00 - COMT Variants and Dopamine00:10:00 - Dopamine Receptor Genes00:11:00 - Strategies for Managing Genetics00:12:00 - Genetics Program Announcement00:13:00 - Custom Recommendations Based on Genetics00:15:00 - The Role of Serotonin and Oxytocin00:16:00 - Genetic Influences on Eating Behaviors00:18:00 - Stress Response and Emotional Eating00:20:00 - The Importance of Awareness00:22:00 - BDNF and Exercise00:23:00 - Micro-Dosed Lithium and Mood00:24:00 - Genetic Predispositions to Worry00:25:00 - Empowerment Through Genetic Awareness00:26:00 - Preview of Next Episode on Eating Genetics00:27:00 - Enrollment for Genetics Program00:28:00 - Closing RemarksWork with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠⁠⁠⁠⁠Enroll TODAY⁠⁠⁠⁠⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠⁠⁠⁠⁠Enroll HERE⁠⁠⁠⁠⁠⁠• The Fit Collective® x InBody USA/Canada – Get 15% off select models. ⁠⁠⁠⁠⁠⁠Click HERE⁠
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    29 mins
  • 262: Stress-Induced Hunger: Tools and Insights

    262: Stress-Induced Hunger: Tools and Insights
    May 8 2025
    Episode Summary: In this episode, Dr. Ali Novitsky — expert in obesity medicine — explores the powerful link between stress and hunger. While many recognize stress affects eating, Dr. Novitsky explains the underlying science, behavioral patterns, and offers tools to manage stress-driven eating with compassion.Understanding Stress ResponsesDr. Novitsky explains that responses to stress vary widely. Some lose their appetite during stress, while others overeat. This depends on physiology, past experiences, and genetics. It’s not about willpower; it’s about biology and behavior.The Role of HormonesAdrenaline (acute stress): Suppresses hunger during “fight or flight” by slowing digestion.Cortisol (chronic stress): Increases appetite and cravings, especially for sugar and fat.Ghrelin: The “hunger hormone,” rises with stress, intensifying hunger cues.Leptin: The “fullness hormone,” can be blunted by chronic stress, leading to overeating.Acute vs. Chronic StressShort-term stress may shut down appetite. Chronic stress, however, causes lasting hormonal shifts that increase hunger, slow metabolism, and may cause leptin resistance. Dr. Novitsky explains how chronic stress and dieting can disrupt satiety signals and lead to weight challenge — even in those with a “normal” BMI.Behavioral & Genetic ComponentsCoping with food often starts in childhood. Learned behaviors and genetic predispositions influence whether one turns to food under stress. Dr. Novitsky shares her personal experience using food for emotional comfort, highlighting the importance of empathy over shame.Tools to Navigate Stress EatingSomatic Stress Scale (1–10) from DBT helps identify rising stress before acting on it.Mindful Pauses: Ask, “Am I hungry or triggered?”Compassionate Self-Talk: Replace guilt with curiosity.Nourishing Alternatives: Movement, breathwork, journaling, or support.Regulate First: Focus on emotional regulation before dietary restriction.Key InsightManaging stress is a foundation for managing hunger. When we understand our body’s signals and respond with awareness and kindness, we create sustainable habits. Dr. Novitsky reminds us we’re human, not broken—and we’re in this together.Final ThoughtThere’s no shame in stress eating. With knowledge, tools, and compassion, we can make empowered, healthier choices. Dr. Novitsky signs off with gratitude and love.Timestamps00:00:22 - Overview of Stress and Hunger00:00:52 - Individual Responses to Stress00:01:25 - Genetics and Stress Response00:01:46 - Acute vs. Chronic Stress00:02:06 - Hormones Involved in Stress Response00:02:28 - Adrenaline and Acute Stress00:03:43 - Cortisol and Chronic Stress00:05:00 - Insulin and Blood Sugar00:05:20 - Ghrelin and Hunger00:06:13 - Weight Loss and Stress00:06:47 - Leptin and Satiety00:07:30 - Leptin Resistance Explained00:08:02 - Normal Weight Obesity00:09:05 - Critique of BMI00:10:12 - Leptin Resistance and Metabolic Rate00:11:22 - Chronic Dieting and Leptin Resistance00:12:01 - Summary of Hormones and Stress00:13:43 - Genetic Component of Emotional Eating00:18:09 - Empathy and Emotional Eating00:21:09 - Identifying Patterns of Stress Eating00:24:08 - Recognizing Stress Levels00:25:01 - Stress Scale and Emotional Regulation00:27:07 - Chronic Stress and Hunger00:29:04 - Positive Stress and Dysregulation00:30:09 - Conclusion and Final ThoughtsFollow Dr. Ali Novitsky on Socials⁠⁠⁠⁠⁠TikTok⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube⁠⁠⁠⁠Work with Dr. Ali• Beginner Strength Training Program – 12 months for only $199! ⁠⁠⁠⁠⁠Enroll TODAY⁠⁠⁠⁠⁠• Total Fitness Program – A 12-month mind-body experience. ⁠⁠⁠⁠⁠Enroll HERE⁠⁠⁠⁠⁠• The Fit Collective® x InBody USA/Canada – Get 15% off select models. ⁠⁠⁠⁠⁠Click HERE⁠
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    31 mins
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