101 Theory Drive
A Neuroscientist's Quest for Memory
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Narrated by:
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Stephen Hoye
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By:
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Terry McDermott
About this listen
It's not fiction: Gary Lynch is the real thing, the epitome of the rebel scientist - malnourished, contentious, inspiring, explosive, remarkably ambitious, consistently brilliant. He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain's memory machine has begun to pay off.
Award-winning journalist Terry McDermott spent nearly two years observing Lynch at work and now gives us a fascinating and dramatic account of daily life in Lynch's lab - the highs and lows, the drudgery and eureka moments, the agonizing failures. He provides detailed, lucid explanations of the cutting-edge science that enabled Lynch to reveal the inner workings of the molecular machine that manufactures memory. And he explains where Lynch's sights are now set: on drugs that could fix that machine when it breaks, drugs that would enhance brain function during the memory process and that hold out the possibility of cures for a wide range of neurological conditions, including Alzheimer's, Parkinson's, and Attention Deficit Hyperactivity Disorder (ADHD). Here is an essential story of science, scientists, and scientific achievement - galvanizing in the telling and thrilling in its far-reaching implications.
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How come I can never find my keys? Why don't I sleep as well as I used to? Why do my friends keep repeating the same stories? What can I do to keep my brain sharp? Scientists know. Brain Rules for Aging Well, by developmental molecular biologist Dr. John Medina, gives you the facts - and the prescription to age well - in his signature engaging style. With so many discoveries over the years, science is literally changing our minds about the optimal care and feeding of the brain. All of it is captivating. A great deal of it is unexpected.
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Scientific and practical
- By symya08 on 04-29-18
By: John Medina
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Time, Love, Memory
- A Great Biologist and His Quest for the Origins of Behavior
- By: Jonathan Weiner
- Narrated by: Kevin Pariseau
- Length: 11 hrs and 37 mins
- Unabridged
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Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.
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This is a profound science book
- By Timothy A. Smith on 05-12-10
By: Jonathan Weiner
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On Intelligence
- By: Jeff Hawkins, Sandra Blakeslee
- Narrated by: Jeff Hawkins, Stefan Rudnicki
- Length: 9 hrs and 22 mins
- Unabridged
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Jeff Hawkins, the man who created the PalmPilot, Treo smart phone, and other handheld devices, has reshaped our relationship to computers. Now he stands ready to revolutionize both neuroscience and computing in one stroke, with a new understanding of intelligence itself.
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Epiphany
- By James on 03-14-05
By: Jeff Hawkins, and others
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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Tomorrowland
- Our Journey From Science Fiction to Science Fact
- By: Steven Kotler
- Narrated by: Tom Parks
- Length: 8 hrs and 58 mins
- Unabridged
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New York Times, Wired, Atlantic Monthly, Discover bestselling author Steven Kotler has written extensively about those pivotal moments when science fiction became science fact...and fundamentally reshaped the world. Now he gathers the best of his best, updated and expanded upon, to guide listeners on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives.
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Covers a lot of different topics in many industries
- By ErnieA on 06-27-15
By: Steven Kotler
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The Performance Cortex
- How Neuroscience Is Redefining Athletic Genius
- By: Zach Schonbrun
- Narrated by: Thomas Vincent Kelly
- Length: 10 hrs and 21 mins
- Unabridged
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Why couldn't Michael Jordan, master athlete that he was, hit a baseball? Why can't modern robotics come close to replicating the dexterity of a five-year-old? Why do good quarterbacks always seem to know where their receivers are?In this deeply researched book, sports and business reporter Zach Schonbrun explores what actually drives human movement and its spectacular potential. The groundbreaking work of two neuroscientists in Major League Baseball is only the beginning.
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Excellent!
- By MD on 07-01-23
By: Zach Schonbrun
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- By: Kat Arney
- Narrated by: Kat Arney
- Length: 8 hrs and 39 mins
- Unabridged
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- By AraSevera on 05-15-16
By: Kat Arney
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Autopilot
- The Art & Science of Doing Nothing
- By: Andrew Smart
- Narrated by: Kevin Free
- Length: 3 hrs and 51 mins
- Unabridged
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Andrew Smart wants you to sit and do nothing much more often - and he has the science to explain why. At every turn we’re pushed to do more, faster, and more efficiently: That drumbeat resounds throughout our wage-slave society. Multitasking is not only a virtue, it’s a necessity. But Andrew Smart argues that slackers may have the last laugh. The latest neuroscience shows that the “culture of effectiveness” is not only ineffective, it can be harmful to your well-being.
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Not worth it.
- By B Lee on 04-30-14
By: Andrew Smart
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Mind Wide Open
- Your Brain and the Neuroscience of Everyday Life
- By: Steven Johnson
- Narrated by: Alan Sklar
- Length: 8 hrs and 7 mins
- Unabridged
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Brilliantly exploring today's cutting edge brain research, Mind Wide Open allows readers to understand themselves and the people in their lives as never before. Using a mix of experiential reportage, personal storytelling, and fresh scientific discovery, Steven Johnson describes how the brain works and how its systems connect to the day-to-day realities of individual lives.
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A totally new perspective on life
- By Jonathan on 09-16-04
By: Steven Johnson
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Permanent Present Tense
- The Unforgettable Life of the Amnesic Patient, H.M.
- By: Suzanne Corkin
- Narrated by: Pam Ward
- Length: 13 hrs and 15 mins
- Unabridged
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Permanent Present Tense tells the incredible story of Henry Gustav Molaison, known only as H. M. until his death in 2008. In 1953, at the age of 27, Molaison underwent a dangerous "psychosurgical" procedure intended to alleviate his debilitating epilepsy. The surgery went horribly wrong, and when Molaison awoke he was unable to store new experiences. For the rest of his life, he would be trapped in the moment. But Molaison’s tragedy would prove a gift to humanity.
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Read Luke Dittrich's "Patient H.M." first...
- By Douglas on 11-07-16
By: Suzanne Corkin
What listeners say about 101 Theory Drive
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Kathy
- 08-17-10
Great Science Writing
Wonderful science writing, excellent descriptions and use of humor. This isn't a book to listen to while doing something else -- it needs your full attention. I kept wanting to take notes!
Great primer for the novice and review for the experienced -- especially those who find themselves teaching complicated neuro science in lay terms.
It is also an up-close-and-personal look at the difficulties of bio-research, the FDA and the personalities involved in neuro-reseach. Well written, well narrated. Stephen Hoye was the perfect choice for this one
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8 people found this helpful
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Overall
- Roy
- 08-23-10
Entertaining and Informative
In this book Terry McDermott aptly tells the story of Gary Lynch and his twenty year effort to understand the biochemical process and brain functions that support human memory. But wait - there is more. McDermott tells the story in a very compelling way, he explains the science in easy to understand terms, and describes the primary characters very well. If you have an interest in neurosocience, this is a good, non-technical book. Readers will gain insight into memory and better understand how the research contributes to that understanding.
In sum, this is an informative, well written book. Stephen Hoye does his usual best in the great reading.
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10 people found this helpful
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- Micky Keck
- 10-12-10
Easy and entertaining listen on a complex subject
I really enjoyed this book and how it covered the very complex topic of memory and brain functions without being boring or overly technical. The story of how memory theory progressed over time in the Lynch lab and around the world was well told and included many interesting characters that you would not think would exist in a research environment.
I bought this book on the hope that it would be entertaining and educational and it succeeded on both counts. I highly recommend this book for those who like science and would like to better understand the process by which new ideas must go through to be accepted by the masses.
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7 people found this helpful
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Overall
- Will
- 05-14-10
Pretty Dang Funny
This audiobook chronicles the amazing career of a brilliant neuroscientist, who--how shall we say?--let's it all hang out. I was equally educated and entertained. The star of the book, Gary Lynch, strikes me as a cross between Carl Sagan and Oscar Madison (from the famed '70s TV Show, The Odd Couple). Gary Lynch comes through, loud and clear as a three-dimensional, provocative, and irreverent scientist. He regales all who listen with deep scientific thoughts and occasional "F-bombs," aimed mostly at jealous peer-reviewers, scientist-lemmings, and college administrators, who do nothing but thwart his greatness. Follow Gary in his journey to discover the physical, neurological manifestation of "memory" inside the brain. Listening to this audiobook, you will feel as if you are spending quality time with a rockstar of sorts. Learn and grow, as Gary lays out his wondrous neuroscientific wonderings about the brain, supported by scientific data that makes sense--even to lay people like me. Kudos to the narrator of the audiobook, who does a great job of injecting colorful voice inflections--especially when he quotes Gary Lynch in his refreshing moments of high sarcasm and choice profanity. Listening will make you smarter, or at least make you feel smarter. Oddly, I feel as if I got to know Gary Lynch and his merry band of lab-students, after listening to their real-life trials and tribulations, replete with scientific advances and setbacks. I wonder what that scientist-dude Gary is up to now. Maybe a sequel will come out? Hope so. I'll keep an eye out for 201 Theory Drive.
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14 people found this helpful
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Overall
- Jeb
- 02-27-11
Great science; great story
An epic neuroscience tale featuring the whacky, brilliant, frequently hilarious, iconoclast researcher Gary Lynch. A fascinating view of the chain of discoveries that explain how memory forms in the brain.
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- Joe
- 04-18-10
Fascinating tale of a scientific maverick's lab
Disclaimer: I am a psychological scientist, so your enjoyment mileage may differ, but I found 101 Theory Drive a truly fascinating tale. McDermott's detailed account of the scientific (and personal) life of Gary Lynch--who first correctly worked out the neurological bases of memory formation in the brain--is full of interesting details about the life and work of a brilliant thinker and scientific investigator...warts, setbacks and all. It's got a lot of physiological detail, which may bore/confuse some readers, but it does not require a lot of knowledge to follow, and it is truly fascinating if you are at all interested in how the brain becomes "mind". I highly recommend this book for anyone interested in the way science REALLY works and in how creative thinkers often work.
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14 people found this helpful
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- Lisa
- 04-06-12
Narrator needs work on characterization.
What did you like best about 101 Theory Drive? What did you like least?
The explanation of science is clear. The ability of the narrator to portray different characters is very awkward and uncomfortable.
Any additional comments?
It takes work, but why can't 2 narrators do one book. If someone's strength is description, let them do that and let others do characters.
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1 person found this helpful
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- Bill
- 03-10-11
Fascinating! Interesting, accessible science
This book charts the life work of a fascinating, complex man in his effort to understand the mechanics of of memory. The biographical approach and the brilliant treatment of complex information make the science accessible to everyone with an interest. And the nature of the scientist keeps the 'read' very interesting.
I really enjoyed this book.
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1 person found this helpful
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- Wade T. Brooks
- 06-25-12
Great Read
Mechanisms of synaptic plasticity: LTP, glutamate receptors and cell adhesion molecules, oh my....
Fascinating book about neurobiologist Gary Lynch at UC Irvine, the way the brain records memory, and quite a bit about how academic science and publishing works. As a bonus: brain drugs and possible cures for diseases including ADHD and alzheimer's. WAIT THAT'S NOT ALL, if you order right now.... mapping of the brain and an overview of the startup biotech craze of the '90s.
For as much technical neurobiology as is in this book (and not being a neurobiologist) the story was very engrossing.
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1 person found this helpful
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Overall
- Jeremy Jones
- 04-06-11
Kinda boring and didn't really go anywhere
I did find a few parts quite interesting, but on the whole I was disappointed. I had just finished "The Talent Code" and was looking for more information regarding the balance between brain physiology and behavior, or at the very least, a better understanding of the chemistry of memory. Honestly, it could have used a bit more information regarding the science, and less about the politics of University funding.
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1 person found this helpful