Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

The plague raging through London in 1665 has emptied the city. The only people left are those too poor to flee or those who selflessly struggle to control the contagion and safeguard the capital's future. Amongst them, though, are those prepared to risk their health for money - those who sell dubious 'cures' and hawk food at wildly inflated prices. Also amongst them are those who hold in their hands the future of the city's most iconic building - St Paul's Cathedral.

In the sapping summer heat of 1665, there is little celebration in London of the naval victory at the Battle of Lowestoft. The King, his retinue and anyone with sufficient means has fled the plague-ridden city, its half-deserted streets echoing the sound of bells tolling the mounting number of deaths. Those who remain clutch doubtful potions to ward off the relentless disease and dart nervously past shuttered buildings, watchful for the thieves who risk their lives to plunder what has been left behind.

Salisbury, 1226. A young pregnant woman is found tangled in reeds in the river Avon, her identity a mystery. Grieving widow Ela Longespée is determined to succeed her husband as sheriff of Salisbury, and quickly takes charge of the investigation. She soon finds herself in the thick of a neighborhood scandal and a struggle to maintain her authority. With multiple suspects, can she identify the true killer?

England, 1925. After years shut away from the world, former detective Lord Edgington of Cranley Hall plans a grand ball to celebrate his seventy-fifth birthday. But when someone starts bumping off members of his scheming family, the old man enlists his teenage grandson to help find the killer, before one of them is next.

December 1927. Mystery-writer Marius Quin has one previous bestseller, endless looming mortgage payments, and no idea how to write his next book. When his childhood friend Lady Isabella Montague invites him to an intimate New Year’s Eve party hosted by a narcissistic actor, Marius seizes upon the distraction. With his perpetually glum Basset hound along for the ride, he navigates the snowy lanes to the opulent estate of Everham Hall. As the celebrations begin, fireworks light up the sky, champagne corks pop, and then the host is murdered…

At the end of her first unsuccessful season out in society, Lady Georgiana has all but given up on attracting a suitable man - until she receives an invitation to a masked Halloween ball at Broxley Manor. Georgie is uncertain why she was invited, until she learns that the royal family intends to marry her off to a foreign prince, one reputed to be mad.

London, September 1666. The Great Fire rages through the city, consuming everything in its path. Even the impregnable cathedral of St. Paul's is engulfed in flames and reduced to ruins. Among the crowds watching its destruction is James Marwood, son of a disgraced printer and reluctant government informer. In the aftermath of the fire, a semi-mummified body is discovered in the ashes of St. Paul's, in a tomb that should have been empty. The man's body has been mutilated, and his thumbs have been tied behind his back.

The much-feared and hated Eudo - the Lord Bishop of Winchester's clerk - is bludgeoned to death in Pershore Abbey and laid before the altar in the attitude of a penitent. Everyone who had contact with him had reason to dislike him, but who had reason to kill him? The Sheriff of Worcestershire's thief taker, wily Serjeant Catchpoll, and his new and unwanted superior, Undersheriff Hugh Bradecote, have to find the answer. And as the walls of the abbey close in on the suspects, the killer strikes again....

At the end of his Grand Tour, somewhere between Athens and Constantinople, Christian Selwyn, the young Earl of Hazelmere, vanished—seemingly without trace. Time passes. In London, his uncle and cousin move into his home, while his unofficial fiancée, Sophia, is left desolate and in limbo.

Miss Busby helped Major Heathcliff Lennox solve a series of murders at Bloxford in the Cotswolds. Now, she finds herself drawn into a new murder, but this time, it's just her, and she must rely on her sharp mind and sharper wits to catch a Cotswolds killer, along with a handsome police inspector and a reporter who's keen to make her mark.

The Earl of Wrexford possesses a brilliant scientific mind, but boredom and pride lead him to reckless behavior. He does not suffer fools gladly. So when pompous, pious Reverend Josiah Holworthy publicly condemns him for debauchery, Wrexford unsheathes his rapier-sharp wit and strikes back. As their war of words escalates, London's most popular satirical cartoonist, A. J. Quill, skewers them both.

As England slides into Civil War, master-goldsmith and money-lender, Luciano Falcieri del Santi embarks on his own hidden agenda. A chance meeting one dark night results in an unlikely friendship with Member of Parliament, Richard Maxwell. Richard’s daughter, Kate - a spirited girl who vows to hold their home against both Cavalier and Roundhead - soon finds herself fighting an involuntary attraction to the clever, magnetic, and diabolically beautiful Italian.

Oxford, Spring 1353. When young bookseller Nicholas Elyot discovers the body of student William Farringdon floating in the river Cherwell, it looks like a drowning. Soon, however, Nicholas finds evidence of murder. Who could have wanted to kill this promising student? As Nicholas and his scholar friend Jordain try to unravel what lies behind William's death, they learn that he was innocently caught up in a criminal plot.

England, 1364: When married off at aged twelve to an elderly farmer, brazen redheaded Eleanor quickly realizes it won’t matter what she says or does, God is not on her side—or any poor woman’s for that matter. But then again, Eleanor was born under the joint signs of Venus and Mars, making her both a lover and a fighter.