A magnificently reported and soulfully crafted exploration of the human immune system - the key to health and wellness, life and death. An epic, first-of-its-kind audiobook, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize-winning New York Times journalist.

On May 6, 2010, financial markets around the world tumbled simultaneously and without warning. In the span of five minutes, a trillion dollars of valuation was lost. The Flash Crash, as it became known, represented the fastest drop in market history. When share values rebounded less than half an hour later, experts around the globe were left perplexed. A real-life financial thriller, Flash Crash uncovers the remarkable, behind-the-scenes narrative of a mystifying market crash, a globe-spanning investigation into international fraud, and the man at the center of them both.

Former New York Times columnist Anand Giridharadas takes us into the inner sanctums of a new gilded age, where the rich and powerful fight for equality and justice any way they can--except ways that threaten the social order and their position atop it.

In May 1971, Pam Jackson and Sherri Miller were two seventeen-year-olds driving to an end-of-the-school-year party in a rundown Studebaker Lark, when they seemingly disappeared off the face of the earth. Police back then didn't do enough to try and find them. Investigators thirty years later did too much. Two families endure decades of pain as they await answers of what happened to their girls. When a third family is pulled into the mystery, they quickly learn their nightmare is just beginning.

If it weren't for the 57 bus, Sasha and Richard never would have met. Both were high school students from Oakland, California, one of the most diverse cities in the country, but they inhabited different worlds. Sasha, a white teen, lived in the middle-class foothills and attended a small private school. Richard, a black teen, lived in the crime-plagued flatlands and attended a large public one. Each day, their paths overlapped for a mere eight minutes. But, one afternoon, on the bus ride home from school, a single reckless act left Sasha severely burned.

In this volume, Steven Johnson explores the history of innovation over centuries, tracing facets of modern life (refrigeration, clocks, and eyeglass lenses, to name a few) from their creation by hobbyists, amateurs, and entrepreneurs to their unintended historical consequences. Filled with surprising stories of accidental genius and brilliant mistakes - from the French publisher who invented the phonograph before Edison but forgot to include playback, to the Hollywood movie star who helped invent the technology behind Wi-Fi and Bluetooth.

Shulem Deen was raised to believe that questions are dangerous. As a member of the Skverers, one of the most insular Hasidic sects in the US, he knows little about the outside world - only that it is to be shunned. His marriage at 18 is arranged, and several children soon follow.

In 1850s South Carolina, an enslaved woman named Rose faced a crisis: the imminent sale of her daughter Ashley. Thinking quickly, she packed a cotton bag for her with a few items, and, soon after, the nine-year-old girl was separated from her mother and sold. Decades later, Ashley’s granddaughter Ruth embroidered this family history on the sack in spare, haunting language. Historian Tiya Miles carefully traces these women’s faint presence in archival records, and, where archives fall short, she turns to objects, art, and the environment to write a singular history of slavery.

Until the End of Time is Brian Greene's breathtaking new exploration of the cosmos and our quest to find meaning in the face of this vast expanse. Greene takes us on a journey from the big bang to the end of time, exploring how lasting structures formed, how life and mind emerged, and how we grapple with our existence through narrative, myth, religion, creative expression, science, the quest for truth, and a deep longing for the eternal.

CNN Senior Supreme Court Analyst Joan Biskupic provides an urgent and inside look at the history-making era in the Supreme Court during the Trump and post-Trump years, from its seismic shift to the Right to its controversial decisions, including its reversal of Roe v. Wade, based on access to all the key players.

As hundreds of rescue workers waited on the ground, United Airlines Flight 232 wallowed drunkenly over the bluffs northwest of Sioux City. The plane slammed onto the runway and burst into a vast fireball. The rescuers didn't move at first: nobody could possibly survive that crash. And then people began emerging from the summer corn that lined the runways. Miraculously, 184 of 296 passengers lived. No one has ever attempted the complete reconstruction of a crash of this magnitude.

In early 2000, Adnan Syed was convicted and sentenced to life plus thirty years for the murder of his ex-girlfriend Hae Min Lee, a high school senior in Baltimore, Maryland. Syed has maintained his innocence, and Rabia Chaudry, a family friend, has always believed him. By 2013, after almost all appeals had been exhausted, Rabia contacted Sarah Koenig, a producer at This American Life, in hopes of finding a journalist who could shed light on Adnan’s story. In 2014, Koenig's investigation turned into Serial, a Peabody Award-winning podcast with more than 500 million international listeners.

We human beings share 98 percent of our genes with chimpanzees. Yet humans are the dominant species on the planet - having founded civilizations and religions, developed intricate and diverse forms of communication, learned science, built cities, and created breathtaking works of art - while chimps remain animals concerned primarily with the basic necessities of survival. What is it about that two percent difference in DNA that has created such a divergence between evolutionary cousins?

The tipping point is that magic moment when an idea, trend, or social behavior crosses a threshold, tips, and spreads like wildfire. Just as a single sick person can start an epidemic of the flu, so too can a small but precisely targeted push cause a fashion trend, the popularity of a new product, or a drop in the crime rate. This widely acclaimed bestseller, in which Malcolm Gladwell explores and brilliantly illuminates the tipping point phenomenon, is already changing the way people throughout the world think about selling products and disseminating ideas.

Growing up, Lisa Nikolidakis tried to make sense of her childhood, which was scarred by abuse, violence, and psychological terrors so extreme that her relationship with her father was cleaved beyond repair. Having finally been able to leave that relationship behind, surviving meant forgetting. For years, “I’m fine” was a lie Nikolidakis repeated. Then, on her twenty-seventh birthday, Nikolidakis’s father murdered his girlfriend and her daughter, and turned the gun on himself.

One day in 2002 the 50-year old body of former Pittsburgh Steeler and hall of famer Mike Webster was laid on a cold table in front of pathologist Dr. Bennet Omalu. Webster's body looked to Omalu like the body of a much older man, and the circumstances of his behavior prior to his death were clouded in mystery. But when Omalu cut into Webster's brain, it appeared to be normal. Something didn't add up.

We know of psychopaths from chilling headlines and stories in the news and movies - from Ted Bundy and John Wayne Gacy to Hannibal Lecter and Dexter Morgan. As Dr. Kent Kiehl shows, psychopaths can be identified by a checklist of symptoms that includes pathological lying; lack of empathy, guilt, and remorse; grandiose sense of self-worth; manipulation; and failure to accept one’s actions. But why do psychopaths behave the way they do? Is it the result of their environment - how they were raised - or is there a genetic component to their lack of conscience?

The mother of Matthew Shepard shares her story about her son's death and the choice she made to become an international gay rights activist.

Shocked by a five-month arson spree that left rural Virginia reeling, Washington Post reporter Monica Hesse drove down to Accomack County to cover the trial of Charlie Smith, who pled guilty to 67 counts of arson. But Charlie wasn't lighting fires alone: he had an accomplice - his girlfriend, Tonya Bundick. Through her depiction of the dangerous shift that happened in their passionate relationship, Hesse brilliantly brings to life the once-thriving coastal community and its distressed inhabitants.

Jeanne Marie Laskas first met the young forensic pathologist Dr. Bennet Omalu in 2009, while reporting a story for GQ that would go on to inspire the movie Concussion. Omalu told her about a day in September 2002, when, in a dingy morgue in downtown Pittsburgh, he picked up a scalpel and made a discovery that would rattle America in ways he’d never intended. Omalu was new to America, chasing the dream, a deeply spiritual man escaping the wounds of civil war in Nigeria.

In the lovely town of Pleasant Valley in upstate New York, the maple trees were ablaze with fall's blood-red color. The air was crisp. And a woman named Susan Fassett left her weekly choir practice at a church - when a killer emerged from the shadows and mercilessly gunned her down.

Jeanne Dominico's fiancé found her body on her kitchen floor. More than forty stab wounds and blows to her head with a blunt instrument had cut her life short. What monster had struck in the heart of a peaceful New England town?

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

12/14/2012 Sandy Hook Elementary School Newtown, Connecticut We remember the numbers: 20 children and 6 adults, murdered in a place of nurture and trust. We remember the names: Teachers like Victoria Soto, who lost her life protecting her students. A shooter named Adam Lanza. And we remember the questions: Outraged conjecture instantly monopolized the worldwide response to the tragedy, while the truth went missing. Here is the definitive journalistic account of Newtown.

A seemingly perfect world held an even more unlikely killer... Julie Keown had a great job, financial security, and a perfect husband who was attending Harvard Business School. But after Julie suddenly died, and doctors discovered she’d been poisoned with the main ingredient in antifreeze, her parents began to suspect that her husband, James, was not so perfect. This blow-by-blow account shows how investigators and state police unraveled James Keown’s chilling web of deceit.

Jamie Wagner is a young lawyer who is happy to be flying under the radar at a large firm doing background research for the partners. It's not that he isn't smart. He is. It's just that hard work, the whole legal world, isn't really his thing. Underachiever? Yes. Content? At least until the firm puts him on a case that turns his whole world upside down.

The dramatic memoir of the journalist who was held hostage in a high-security prison in Tehran for 18 months and whose release - which almost didn’t happen - became a part of the Iran nuclear deal.

To all appearances, Dennis Rader was a model citizen in the small town of Park City, Kansas, where he had lived with his family almost his entire life. He was a town compliance officer, a former Boy Scout leader, the president of his church congregation, and a seemingly ordinary father and husband. But Rader's average life belied the existence of his dark, sadistic other self: he was the BTK serial killer.

Three years ago, John Schwartz, a national correspondent for the New York Times, got the call that every parent hopes never to receive: His 13-year-old son, Joe, was in the hospital following a suicide attempt. Mustering the courage to come out to his classmates, Joe had delivered a tirade about homophobic and sexist attitudes that was greeted with unease and confusion by his fellow students. Hours later, he took an overdose of pills.

This riveting inside story of the intense search for the Salt Lake City teenager who was kidnapped from her bed reveals never-before-told details of the largest investigation in Utah state history. Paced like a thriller, this true account moves between the parallel stories of the searchers and the abductor. Going beyond a mere eyewitness account, the book includes information culled from interviews with more than 150 people involved in the search and investigation, notes from family meetings, and memos from law enforcement officials.