New York, 1960: For Benny Lament, music is his entire life. With his father’s deep ties to the mob, the Bronx piano man has learned that love and family can get you in trouble. So he keeps to himself, writing songs for other musicians, avoiding the spotlight…until the night his father brings him to see Esther Mine sing. Esther is a petite powerhouse with a gorgeous voice. And when Benny writes a hit song and performs it with her, their collaboration thrusts the duo onto the national stage…and stirs up old issues and new scrutiny that the mob--and Benny--would rather avoid.

Rachel is a student working at a bookstore when she meets James, and it’s love at first sight. Effervescent and insistently heterosexual, James soon invites Rachel to be his roommate and the two begin a friendship that changes the course of both their lives forever. Together, they run riot through the streets of Cork city, trying to maintain a bohemian existence while the threat of the financial crash looms before them.

When beautiful and successful Susan Harris jumps from the roof of her apartment building, she sets a tremor through her New York City mothers’ group that forces them all to look at one another with new cynicism: How could this have happened right under their noses? To one of them? Between her death and the harrowing private school admission season on the horizon, these women are forced to explore the hard truths about themselves.

It was supposed to be the perfect weekend away. Six very different women travel to a sun-soaked Greek island for a bachelorette trip, to celebrate Lexi’s upcoming wedding. From the glorious ocean views to the quaint tavernas and whitewashed streets, the vacation seems too good to be true. But dangerous undercurrents run beneath the sunset swims and midnight cocktails—because each of the women is hiding a secret. Someone is determined to make sure that Lexi’s marriage never happens—and that one of them doesn’t leave the island alive.

In 1985, Yale Tishman, the development director for an art gallery in Chicago, is about to pull off an amazing coup, bringing in an extraordinary collection of 1920s paintings as a gift to the gallery. Yet as his career begins to flourish, the carnage of the AIDS epidemic grows around him. One by one, his friends are dying and after his friend Nico's funeral, the virus circles closer and closer to Yale himself. Soon the only person he has left is Fiona, Nico's little sister.

After 27 years of marriage and three children, Anna Oh - wife, mother, outsider artist - has fallen in love with Viveca, the wealthy Manhattan art dealer who orchestrated her success. They plan to wed in the Oh family’s hometown of Three Rivers in Connecticut. But the wedding provokes some very mixed reactions and opens a Pandora’s Box of toxic secrets - dark and painful truths that have festered below the surface of the Ohs' lives.

Kelley Quinn is the owner of Nantucket's Winter Street Inn and the proud father of four, all of them grown and living in varying states of disarray. Patrick, the eldest, is a hedge fund manager with a guilty conscience. Kevin, a bartender, is secretly sleeping with a French housekeeper named Isabelle. Ava, a school teacher, is finally dating the perfect guy but can't get him to commit. And Bart, the youngest and only child of Kelley's second marriage to Mitzi, has recently shocked everyone by joining the Marines.

Claire has a problem with setting limits. All her life she has taken on every responsibility, assumed every burden, granted every request. Claire wants it all—and in the eyes of her friends, she has it: a devoted husband, four beautiful children, even a successful career as an artist. So when she agrees to chair the committee for Nantucket's social event of the year, she knows she can handle it. Claire can handle anything. But when planning the gala propels her into the orbit of billionaire Lock Dixon, unexpected sparks begin to fly.

Rachel Blum and Andy Landis are eight years old when they meet late one night in an ER waiting room. Born with a congenital heart defect, Rachel is a veteran of hospitals, and she's intrigued by the boy who shows up all alone with a broken arm. He tells her his name. She tells him a story. After Andy's taken back to the emergency room and Rachel's sent back to her bed, they think they'll never see each other again.

Austin’s Zilker Park neighborhood is a wonderland of greenbelt trails, live music, and moms who drink a few too many margaritas. Whitney, Annette, and Liza have grown thick as thieves as they have raised their children together for 15 years, believing that they can shelter them their children from an increasingly dangerous world. Their friendship is unbreakable - as safe as the neighborhood where they've raised their sweet little boys. Or so they think.

Laine Francis believes there’s a place for everything—and New York, where her family lives, isn’t her place. But no sooner does the professional organizer’s marriage begin to unravel than her sisters drop another bomb on her: their mother, Sally, may have dementia, and they need Laine to come home.

Lucy and Owen, ambitious, thoroughly-therapized New Yorkers, have taken the plunge, trading in their crazy life in a cramped apartment for Beekman, a bucolic Hudson Valley exurb. They've got a 200-year-old house, an autistic son obsessed with the Titanic, and 17 chickens, at last count. It's the kind of paradise where stay-at-home moms team up to cook the school's "hot lunch", dads grill grass-fed burgers, and, as Lucy observes, "chopping kale has become a certain kind of American housewife's version of chopping wood".

Every summer the Newton family retreats to their beloved home on Nantucket for three months of sunshine, cookouts, and bonfires on the beach. But this summer will not be like any other. When Arch Newton, a prominent New York attorney, dies in a plane crash on his way home from a business trip, his beautiful widow, Beth, can barely keep things together. Above all, though, she decides that she must continue the family tradition of going to Nantucket, and at the same time fulfill a promise that Arch made before he died.

One morning, Deming Guo's mother, an undocumented Chinese immigrant named Polly, goes to her job at the nail salon and never comes home. No one can find any trace of her. With his mother gone, 11-year-old Deming is left with no one to care for him. He is eventually adopted by two white college professors who move him from the Bronx to a small town upstate. They rename him Daniel Wilkinson in their efforts to make him over into their version of an "all-American boy".

Birdie Cousins has thrown herself into the details of her daughter Chess's lavish wedding, from the floating dance floor in her Connecticut back yard to the color of the cocktail napkins. Like any mother of a bride-to-be, she is weathering the storms of excitement and chaos, tears and joy. But Birdie, a woman who prides herself on preparing for every possibility, could never have predicted the late-night phone call from Chess, abruptly announcing that she's cancelled her engagement. It's only the first hint of what will be a summer of upheavals and revelations.