Breaking Through
My Life in Science
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Narrated by:
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Eva Magyar
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By:
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Katalin Karikó
About this listen
A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
“Katalin Karikó’s story is an inspiration.”—Bill Gates
“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry
A KIRKUS REVIEWS BEST BOOK OF THE YEAR
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
©2023 Katalin Karikó (P)2023 Random House AudioListeners also enjoyed...
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Critic reviews
“A riveting testament to resilience and the power of unwavering belief, Breaking Through charts an inspirational journey from growing up in postwar communist Hungary to transforming the world with mRNA.”—Jennifer Doudna, Nobel Prize laureate in chemistry and author of A Crack in Creation
“Katalin Karikó’s story is an inspiration. Anyone who has ever doubted that science, innovation, and persistence can change the world should read this book.”—Bill Gates, #1 New York Times bestselling author of How to Avoid a Climate Disaster
“Karikó’s proven recipe (from the creative Hungarian kitchen) for a breakthrough in science: Start with an insatiable curiosity in education and research. Then, for a few decades, look for gaps in knowledge; work hard for years to fill some of them; don’t give up because of difficulties or circumstances; and, finally, seize the opportunity to help solve one painful problem of humanity, thereby opening new horizons for the future of medicine. Bon appétit, enjoy your sweets!”—Ernő Rubik, inventor of the Rubik’s Cube and author of Cubed
“Katalin Karikó’s remarkable life story, which incidentally began not far from where I spent my childhood, inspires us not to be held back even in the face of severe difficulties. It encourages us to stay strong and follow through with important ideas that can change the world.”—Stefan Hell, Nobel Prize laureate in chemistry
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It’s 2006. After a string of rejections from men who tell her they could never, ever, ever see her “that way,” awkward third-grade teacher Micaela Blei signs up for a mysterious course called “The Divine Feminine,” and feels like she might have found the key to the perfect life. Turns out if you’re an A student, you can get an A in anything–including men. Pretty soon she’s learning to "conjure" her desires with vision boards, flirtations, and even a daring jumbotron viewing party for her, ahem ... "divine center."
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This is about real life.
- By Justin Ortgies on 12-14-24
By: Micaela Blei
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Going Infinite
- The Rise and Fall of a New Tycoon
- By: Michael Lewis
- Narrated by: Michael Lewis
- Length: 9 hrs and 35 mins
- Unabridged
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Performance
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Story
When Michael Lewis first met him, Sam Bankman-Fried was the world’s youngest billionaire and crypto’s Gatsby. CEOs, celebrities, and leaders of small countries all vied for his time and cash after he catapulted, practically overnight, onto the Forbes billionaire list. Who was this rumpled guy in cargo shorts and limp white socks, whose eyes twitched across Zoom meetings as he played video games on the side?
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really expected more rigor from Michael Lewis
- By Wowhello on 10-04-23
By: Michael Lewis
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Maybe You Should Talk to Someone
- A Therapist, HER Therapist, and Our Lives Revealed
- By: Lori Gottlieb
- Narrated by: Brittany Pressley
- Length: 14 hrs and 21 mins
- Unabridged
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One day, Lori Gottlieb is a therapist who helps patients in her Los Angeles practice. The next, a crisis causes her world to come crashing down. Enter Wendell, the quirky but seasoned therapist in whose office she suddenly lands. With his balding head, cardigan, and khakis, he seems to have come straight from Therapist Central Casting. Yet he will turn out to be anything but.
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It was like a hallmark movie being waterboarded into my ears for 15 hours
- By Amazon Customer on 10-01-19
By: Lori Gottlieb
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Except for the author, this book is good!
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Awesome
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Excellent
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Awesome
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A man of worth
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Whether we like it or not, the AI revolution is coming to education. In Brave New Words, Salman Khan, the visionary behind Khan Academy, explores how artificial intelligence and GPT technology will transform learning, and offers a road map for teachers, parents, and students to navigate this exciting (and sometimes intimidating) new world. A pioneer in the field of education technology, Khan examines the ins and outs of these cutting-edge tools and how they will revolutionize the way we learn and teach.
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Honestly, I'm a little disappointed.
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The Radium Girls
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The year was 1917. As a war raged across the world, young American women flocked to work, painting watches, clocks, and military dials with a special luminous substance made from radium. It was a fun job, lucrative and glamorous - the girls themselves shone brightly in the dark, covered head to toe in the dust from the paint. They were the radium girls. As the years passed, the women began to suffer from mysterious and crippling illnesses.
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A simple way to improve the robotic narration
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Entangled Life
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When we think of fungi, we likely think of mushrooms. But mushrooms are only fruiting bodies, analogous to apples on a tree. Most fungi live out of sight, yet make up a massively diverse kingdom of organisms that supports and sustains nearly all living systems. Fungi provide a key to understanding the planet on which we live, and the ways we think, feel, and behave.
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Mycology for Everyone
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The Coming Wave
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We are approaching a critical threshold in the history of our species. Everything is about to change. Soon you will live surrounded by AIs. They will organize your life, operate your business, and run core government services. You will live in a world of DNA printers and quantum computers, engineered pathogens and autonomous weapons, robot assistants and abundant energy.
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Click bait
- By Buyer on 09-11-23
By: Mustafa Suleyman, and others
What listeners say about Breaking Through
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- Jacob Rios
- 10-29-23
a must listen
this book is a must listen. it’s so inspirational and a lesson for how life should be lived.
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- José
- 01-10-24
Inspiring
Kaitlin's memoirs go beyond her major scientific advances to tell of her search for the unknown and her determination and resilience to find it, even without knowing that doing so would save millions of lives. One of the most inspiring stories I have read, but at the same time it reveals how there is a lot to do to support talent, especially women.
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- Linda Hart
- 11-21-23
Remarkable and inspiring story of grit and perseverance
Remarkable and inspiring story of grit and perseverance. Humanity should be forever grateful. Made me wonder how many researchers, particularly women, who quit before seeing the fruits of their labor because of poor leadership in their labs. The reader's accent created the belief that the book was delivered in the author's voice.
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- Amazon Customer
- 11-08-23
Excellent book!
Excellent book! Read it. Wish everyone could read this book. It is a story of grit.
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- Mai Ceesay
- 01-08-24
Phenomenal
Phenomenal and very inspirational. Just wow! Went through several rounds of smiles and cries listening to this book. Thank you for your contribution Dr.!!!
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- Lisa
- 04-06-24
inspiring story
shows how academia works, and how humanity almost missed the contributions of this wonderful scientist.
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- M. Colombo
- 06-02-24
Truly inspiriring
This is an amazing book. Katalin life is truly inspiring. The book it’s well written and well narrated. A Nobel price winner who had to face so many challenges.
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- Stacey
- 08-06-24
Absolutely remarkable!
This is an amazing autobiography by a skilled and determined researcher. She overcame many obstacles to achieve her discoveries and it is fortunate for humanity that she did so, considering how instrumental they were in developing a Covid vaccine. Brava!
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- Josh
- 11-23-24
Love letter to RNA
I enjoyed hearing about this author’s dogged determination in the face of adversity. Her story is inspiring. I admire Katalin Karikó, her voice desperately needs to be heard by the world.
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- Fox2
- 11-27-23
Excellent book
Worthy book to read. Great story that shows the ethics and hard work of Dr. Kariko. Very inspiring and it shows the importance of science in our society. I fully recommend it.
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