Like many women, Clare Pooley found the juggle of a stressful career and family life a struggle, so she left her successful role as a managing partner in one of the world's biggest advertising agencies to look after her family. She knew the change wouldn't be easy, but she never expected to find herself an overweight, depressed, middle-aged mother of three who was drinking more than a bottle of wine a day and spending her evenings Googling 'am I an alcoholic?'

Clare Dunkle seemed to have an ideal life - two beautiful, high-achieving teenage daughters, a loving husband, and a satisfying and successful career as a children's book novelist. But it's when you let down your guard that the ax falls. Just after one daughter successfully conquered her depression, another daughter developed a life-threatening eating disorder.

David Sheff's story is a first: a teenager's addiction from the parent's point of view, a real-time chronicle of the shocking descent into substance abuse and the gradual emergence into hope.

Before meth, Sheff's son, Nic, was a varsity athlete, honor student, and award-winning journalist. After meth, he was a trembling wraith who stole money from his eight-year-old brother and lived on the streets. With haunting candor, Sheff traces the first warning signs, the attempts at rehabilitation, and, at last, the way past addiction. He shows us that, whatever an addict's fate, the rest of the family must care for one another, too, lest they become addicted to addiction.

Marianne has a life others dream of. A beautiful townhouse on the best street in the neighbourhood. Three bright children who are her pride and joy. Sometimes her past still hurts: losing her mother early, growing up in foster care. But her husband, Simon, is always there. A successful surgeon, he’s the envy of every woman they’ve ever met. Flowers, gifts, trips to France: nothing is too good for his family. Then Simon says another woman’s name. The way he lingers on it, Caroline, gives Marianne a shudder of suspicion, but she knows it’s nothing - she can’t entertain this flash of paranoia.

Beloved former ABC 20/20 anchor Elizabeth Vargas reveals her alcohol addiction and anxiety disorder in a shockingly honest and emotional memoir. From the moment she uttered the brave and honest words, "I am an alcoholic," to interviewer George Stephanopoulos, Elizabeth Vargas began writing her story, as her experiences were still raw. Now, in Between Breaths, Vargas discusses her accounts of growing up with anxiety—which began suddenly at the age of six when her father served in Vietnam.

Amy Bloom began to notice changes in her husband, Brian: He retired early from a new job he loved; he withdrew from close friendships; he talked mostly about the past. Suddenly, it seemed there was a glass wall between them, and their long walks and talks stopped. Their world was altered forever when an MRI confirmed what they could no longer ignore: Brian had Alzheimer’s disease.

Twentysomething Nora McInerny Purmort bounced from boyfriend to boyfriend and job to job. Then she met Aaron, a charismatic art director and her kindred spirit. They made mixtapes (and pancakes) into the wee hours of the morning. They finished each other's sentences. They just knew. When Aaron was diagnosed with a rare brain cancer, they refused to let it limit their love. They got engaged on Aaron's hospital bed and married after his first surgery. They had a baby when he was on chemo.

From childhood, Laura James knew she was different. She struggled to cope in a world that often made no sense to her, as though her brain had its own operating system. It wasn't until she reached her 40s that she found out why: Suddenly and surprisingly, she was diagnosed with autism. With a touching and searing honesty, Laura challenges everything we think we know about what it means to be autistic. Married with four children and a successful journalist, Laura examines the ways in which autism has shaped her career, her approach to motherhood, and her closest relationships.

Bryony Gordon has OCD. It's the snake in her brain that has told her ever since she was a teenager that her world is about to come crashing down: that her family might die if she doesn't repeat a phrase five times, or that she might have murdered someone and forgotten about it. It's caused alopecia, bulimia, and drug dependency. And Bryony is sick of it. Keeping silent about her illness has given it a cachet it simply does not deserve, so here she shares her story with trademark wit and dazzling honesty.

The syndicated sex-advice columnist of "Savage Love" tells a no-holds-barred story of an ordinary American couple who want to have a baby, except that in this case, the couple happens to be Savage and his boyfriend.

Moving, harrowing, and ultimately uplifting, Lori Schiller's memoir is a classic testimony to the ravages of mental illness and the power of perseverance and courage. At 17, Lori Schiller was the perfect child - the only daughter of an affluent, close-knit family. Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia.

In the tradition of The Promise of a Pencil and Kisses from Katie comes an inspirational memoir by the founder of Comfort Cases about his turbulent childhood in the foster care system and the countless obstacles and discrimination he endured in adopting his four children.

From the outside, Essie’s life looks idyllic: a loving husband, a beautiful house in a good neighborhood, and a nearby mother who dotes on her grandchildren. But few of Essie’s friends know her secret shame: that in a moment of maternal despair, she once walked away from her newborn, asleep in her carriage in a park. Disaster was avoided, and Essie got better, but she still fears what lurks inside her, even as her daughter gets older and she has a second baby.

Christine Ducommun was a happily married wife and mother of two when, after returning to live in the house of her childhood, she began to experience panic attacks and night terrors. Says the author, "I sought therapy, and there I discovered, to my shock and horror, that I had been sexually abused at the hands of my father at a very early age. I surely didn't want to believe it. But as my mind began to release bizarre flashbacks, my alters began to show themselves.

The complex, deeply binding relationship between mothers and daughters is brought vividly to life in Katie Hafner's remarkable memoir, an exploration of the year she and her mother, Helen, spent working through, and triumphing over, a lifetime of unresolved emotions. Dreaming of a "year in Provence" with her mother, Katie urges Helen to move to San Francisco to live with her and Zoe, Katie's teenage daughter. Katie and Zoe had become a mother-daughter team, strong enough, Katie thought, to absorb the arrival of a 77-year-old woman set in her ways....