Sleep is one of the most important but least understood aspects of our life, wellness, and longevity. Until very recently, science had no answer to the question of why we sleep, or what good it served, or why we suffer such devastating health consequences when we don't sleep. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.

Here are some facts: Women live longer than men. They have stronger immune systems. They're better at fighting cancer and surviving famine, and even see the world in a wider variety of colors. They are simply stronger than men at every stage of life. Why is this? And why are we taught the opposite? To find out, Dr. Sharon Moalem drew on his own medical experiences - treating premature babies in the neonatal intensive care unit; recruiting the elderly for neurogenetic studies; and more - and tried to understand why in every instance men were consistently less likely to thrive.

How did a deadly genetic disease help our ancestors survive the bubonic plagues of Europe? Was diabetes evolution's response to the last Ice Age? Will a visit to the tanning salon help bring down your cholesterol? Why do we age? Why are some people immune to HIV? Can your genes be turned on or off? Survival of the Sickest reveals the answers to these and many other questions as it unravels the amazing connections between evolution, disease, and human health today.

Richard H. Thaler has spent his career studying the radical notion that the central agents in the economy are humans - predictable, error-prone individuals. Misbehaving is his arresting, frequently hilarious account of the struggle to bring an academic discipline back down to earth - and change the way we think about economics, ourselves, and our world.

Economic forces are everywhere around you. But that doesn't mean you need to passively accept whatever outcome those forces might press upon you. Instead, with these 12 fast-moving and crystal clear lectures, you can learn how to use a small handful of basic nuts-and-bolts principles to turn those same forces to your own advantage.

Here is an exceptionally clear introduction to law, covering the main subjects found in the first year of law school, giving us a basic understanding of how it all works. Listeners are introduced to every aspect of the legal system, from constitutional law and the litigation process to tort law, contract law, property law, and criminal law. Feinman illuminates each discussion with many intriguing, outrageous, and infamous cases.

Since Darwin's day, we've been told that sexual monogamy comes naturally to our species. Mainstream science - as well as religious and cultural institutions - has maintained that men and women evolved in families in which a man's possessions and protection were exchanged for a woman's fertility and fidelity. But this narrative is collapsing....

Bill Bryson has been an enormously popular author both for his travel books and for his books on the English language. Now, this beloved comic genius turns his attention to science. Although he doesn't know anything about the subject (at first), he is eager to learn, and takes information that he gets from the world's leading experts and explains it to us in a way that makes it exciting and relevant.

The tipping point is that magic moment when an idea, trend, or social behavior crosses a threshold, tips, and spreads like wildfire. Just as a single sick person can start an epidemic of the flu, so too can a small but precisely targeted push cause a fashion trend, the popularity of a new product, or a drop in the crime rate. This widely acclaimed bestseller, in which Malcolm Gladwell explores and brilliantly illuminates the tipping point phenomenon, is already changing the way people throughout the world think about selling products and disseminating ideas.

The guru to the gurus at last shares his knowledge with the rest of us. Nobel laureate Daniel Kahneman's seminal studies in behavioral psychology, behavioral economics, and happiness studies have influenced numerous other authors, including Steven Pinker and Malcolm Gladwell. In Thinking, Fast and Slow, Kahneman at last offers his own, first book for the general public. It is a lucid and enlightening summary of his life's work. It will change the way you think about thinking. Two systems drive the way we think and make choices, Kahneman explains....

What is the value of a college degree? The four-year college experience is as American as apple pie. So is the belief that higher education offers a ticket to a better life. But with student-loan debt surpassing the $1 trillion mark and unemployment of college graduates at historic highs, people are beginning to question that value. In College (Un)Bound, Jeffrey J. Selingo, editor at large of the Chronicle of Higher Education, argues that America’s higher education system is broken.

Knowledge of the basic ideas and principles of science is fundamental to cultural literacy. But most books on science are often too obscure or too specialized to do the general listener much good.

By the end of on average day in the early 21st century, human beings searching the Internet will amass eight trillion gigabytes of data. This staggering amount of information - unprecedented in history - can tell us a great deal about who we are - the fears, desires, and behaviors that drive us, and the conscious and unconscious decisions we make. From the profound to the mundane, we can gain astonishing knowledge about the human psyche that less than 20 years ago seemed unfathomable.

Ellenberg chases mathematical threads through a vast range of time and space, from the everyday to the cosmic, encountering, among other things, baseball, Reaganomics, daring lottery schemes, Voltaire, the replicability crisis in psychology, Italian Renaissance painting, artificial languages, the development of non-Euclidean geometry, the coming obesity apocalypse, Antonin Scalia's views on crime and punishment, the psychology of slime molds, what Facebook can and can't figure out about you, and the existence of God.

From batting averages and political polls to game shows and medical research, the real-world application of statistics continues to grow by leaps and bounds. How can we catch schools that cheat on standardized tests? How does Netflix know which movies you'll like? What is causing the rising incidence of autism? As best-selling author Charles Wheelan shows us in Naked Statistics, the right data and a few well-chosen statistical tools can help us answer these questions and more.

The Latin term for the female genitalia, pudendum, means “parts for which you should be ashamed”. Until 1651, ovaries were called female testicles. The fallopian tubes are named for a man. Named, claimed, and shamed: Welcome to the story of the female body, as penned by men. Today, a new generation of (mostly) women scientists is finally redrawing the map. With modern tools and fresh perspectives, they’re looking at the organs traditionally bound up in reproduction—the uterus, ovaries, vagina—and seeing within them a new biology of change and resilience.

Sex, Time, and Power offers a tantalizing answer to an age-old question: Why did big-brained Homo sapiens suddenly emerge some 150,000 years ago? The key, according to Shlain, is female sexuality. Drawing on an awesome breadth of research, he shows how, long ago, the narrowness of the newly bipedal human female's pelvis and the increasing size of infants' heads precipitated a crisis for the species. Natural selection allowed for reconfiguration of hormonal cycles, entraining women with the periodicity of the moon - and imbuing women with the concept of time.

Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?

In Missing Microbes, Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now this invisible eden is being irrevocably damaged by some of our most revered medical advances-antibiotics-threatening the extinction of our irreplaceable microbes with terrible health consequences.

An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.

A riveting investigation of the myriad ways that parasites control how other creatures - including humans - think, feel, and act. These tiny organisms can live only inside another animal, and, as McAuliffe reveals, they have many evolutionary motives for manipulating their host's behavior. Far more often than appreciated, these puppeteers orchestrate the interplay between predator and prey.

Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.

A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.

The study of sexual physiology has been a paying career or a diverting sideline for scientists as far-ranging as Leonardo da Vinci and James Watson. The research has taken place behind the closed doors of laboratories, brothels, MRI centers, pig farms, sex-toy R&D labs, and Alfred Kinsey's attic.

Mary Roach, "The funniest science writer in the country", devoted the past two years to stepping behind those doors. In Bonk, Roach shows us how and why sexual arousal and orgasm can be so hard to achieve and what science is doing to slowly make the bedroom a more satisfying place.

Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.

What causes a child to grow up gay or straight? In this book, neuroscientist Simon LeVay summarizes a wealth of scientific evidence that points to one inescapable conclusion: Sexual orientation results primarily from an interaction between genes, sex hormones, and the cells of the developing body and brain. LeVay helped create this field in 1991 with a much-publicized study in Science, where he reported on a difference in the brain structure between gay and straight men. Since then, an entire scientific discipline has sprung up around the quest for a biological explanation of sexual orientation. In this book, LeVay provides a clear explanation of where the science stands today, taking the reader on a whirlwind tour of laboratories that specialize in genetics, endocrinology, neuroscience, cognitive psychology, evolutionary psychology, and family demographics. He describes, for instance, how researchers have manipulated the sex hormone levels of animals during development, causing them to mate preferentially with animals of their own gender. LeVay also reports on the prevalence of homosexual behavior among wild animals, ranging from Graylag geese to the Bonobo chimpanzee.

What to listen to after What to Expect.... A badass, feminist, and personal deep-dive into the science and culture of pregnancy and early motherhood that debunks myths and dated assumptions, offering guidance and camaraderie to women navigating one of the biggest and most profound changes in their lives. Like most first-time mothers, Angela Garbes was filled with questions when she became pregnant. What exactly is a placenta? How does a body go into labor? Why is breast best? What are the signs and effects of postpartum depression?

The story of evolution as you’ve never heard it before. What’s the easiest way to tell species apart? Check their genitals. Researching private parts was long considered taboo, but scientists are now beginning to understand that the wild diversity of sex organs across species can tell us a lot about evolution. Menno Schilthuizen invites listeners to join him as he uncovers the ways the shapes and functions of genitalia have been molded by complex Darwinian struggles.

When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.