Symphony Nelson has weathered more than her share of hardships - in part thanks to the faithfulness and affection of her adopted puppy, Toby. Her formerly chaotic life seems to be settling down, until a peaceful walk in the woods leads Symphony and Toby to the reclusive cabin of Caleb Showalter, who knows more about her past than he's telling.

Mary Thomson is no ordinary woman. She works alongside her husband William cutting firewood to sell in the city, earning the nickname “The Woodcutter’s Wife”. The one thing she cannot seem to handle is the melancholy that has enveloped her...Her world flies apart when William disappears, leaving her with the arduous task of tending their farm by herself...she finds help in the form of a freed slave who offers his help. But fate throws her another dramatic curve, forcing her to make the most difficult choice of her life.

Roscoe Ransom returned home from World War I, broken both in body and spirit, drowning his pain daily in a bottle of whiskey. But even alcohol can’t numb the agony of losing his wife or the fear of trying to raise his son, Junior, alone. However, the mind-numbing predictability of Roscoe’s life as a sharecropper and his role of town sheriff - a job given to him out of pity when he returned from the war - is suddenly upended when a black man in their tiny community is murdered and castrated.

Early one morning in 1929, Mary Seneca Steele spontaneously packs a suitcase, gathers up her son and daughter, and drives away in her abusive and dissolute husband’s brand-new Auburn Phaeton automobile, leaving her privileged life in Charleston behind. It is the beginning of a journey of enlightenment that leads Mary “Sen” to the mountains and mysteries of Appalachia, where she will learn unexpected family secrets, create a new life for herself and her children, and finally experience love and happiness before tragedy will once again test her.

When 15-year-old Marigold becomes pregnant amid the Great Depression, she is rejected by her family and forced to fend for herself. And when she loses her baby in the forest, her whole world turns upside down. She’s even more distraught upon discovering she has an inexplicable power that makes her both beautiful and terrifying - and something of a local legend. Meanwhile, migrant workers Vern and Paul discover a violet-eyed baby and take it upon themselves to care for her.

The McKenzie women, empowered with a formidable history rooted in the foothills of Appalachia, have passed down their folk-healing wisdom through generations. Rosalee, the last living headstrong daughter in Granny McKenzie’s line, soaked up everything she could about the secrets of the forest before a series of tragedies left her alone, without the protection of the women who came before her.

In the ruggedness of the beautiful Kentucky mountains, Honey Lovett has always known that the old ways can make a hard life harder. As the daughter of the famed blue-skinned Troublesome Creek packhorse librarian, Honey and her family have been hiding from the law all her life. But when her mother and father are imprisoned, Honey realizes she must fight to stay free, or risk being sent away for good.

Sugar arrives in the small town of Bigelow, Arkansas, like an ominous storm. She saunters down the street in a blonde wig and spiked heels, cigarette dangling between red-painted lips. Without even speaking to her, the women in town hate her. But when she moves in next door to Pearl, a woman who tragically lost her daughter 15 years earlier, the two women bond over tragic pasts.

Rita and Rosie Stevens are only nine and five years old when their widowed mother marries a violent bully called Jimmy Randall and has a baby boy by him. Under pressure from her new husband, she is persuaded to send the girls to an orphanage, not knowing that the papers she has signed will entitle them to do what they like with the children. And it is not long before the powers that be decide to send a consignment of orphans to their sister institution in Australia. Among them - without their family's consent or knowledge - are Rita and Rosie.

Del Wensley, wife of the most celebrated preacher in Harlan County, tries to mind her place. Until her husband’s infidelity pushes an already strained marriage to a breaking point. Clinging to her last hope for self-respect, Del turns her back on the rigid life she’s known. A coal train is rolling through the valley. With her eyes wide open to the unfamiliar, and to the freedom she craves, Del takes to the rails.

On a stifling summer day, an old Chevy Impala ignored the warning signals and was annihilated by the oncoming train. What no one realized until much later was that the driver had paused just before entering the tracks and kicked a small boy out of the car. A small boy with broken glasses who is clutching a notebook with all his might...but who never speaks.

It's February, 1852, and all around Chicago, Maggie sees postings soliciting "eligible women" to travel to the gold mines of Goosetown. A young seamstress with a small daughter, she has nothing to lose. She joins 43 other women and two pious reverends on the dangerous 2,000-mile journey west. None are prepared for the hardships they face on the trek or for the strengths they didn't know they possessed. Maggie discovers she’s not the only one looking to leave dark secrets behind.

Thirteen-year-old Abby Hubble lives in an unhappy home in the Sierra Nevada foothills where her father makes life miserable for her and her mother, Mary. One day Abby witnesses a man dump a litter of puppies into the nearby river. Diving in to rescue all seven, she knows she won’t be able to bring them home. Afraid for their fate at the pound, she takes them to an abandoned cabin, where all she can offer is a promise that she’ll be back the next day.

Megan waits at the school gates for her six-year-old son, Daniel. As the playground empties, panic bubbles inside her. Daniel is nowhere to be found. According to his teacher, Daniel’s father picked up his son. Except he and Megan are no longer together. After years of being controlled by her cruel husband, Megan finally found the courage to divorce him. Hands trembling, she dials his number, but the line is dead. Six years later, Megan gets the call she has dreamt about for years. Daniel has walked into a police station in a remote town just a few miles away....

Harriet Vanger, a scion of one of Sweden's wealthiest families disappeared over forty years ago. All these years later, her aged uncle continues to seek the truth. He hires Mikael Blomkvist, a crusading journalist recently trapped by a libel conviction, to investigate. He is aided by the pierced and tattooed punk prodigy Lisbeth Salander. Together they tap into a vein of unfathomable iniquity and astonishing corruption.