Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

Known to mankind since prehistoric times, opium is arguably the oldest and most widely used narcotic. Opium: A History traces the drug's astounding impact on world culture - from its religious use by prehistoric peoples to its influence on the imaginations of the Romantic writers; from the earliest medical science to the Sino-British opium wars.

Opium tells the extraordinary and at times harrowing tale of how we arrived at today's crisis, "mak[ing] timely and startling connections among painkillers, politics, finance, and society" (Laurence Bergreen). The story begins with the discovery of poppy artifacts in ancient Mesopotamia, and goes on to explore how Greek physicians and obscure chemists discovered opium's effects and refined its power, how colonial empires marketed it around the world, and eventually how international drug companies developed a range of powerful synthetic opioids that led to an addiction epidemic.

As one of the most potent turning points in the country's modern history, the Opium War has since come to stand for everything that today's China seeks to put behind it. In this dramatic, epic story, award-winning historian Stephen Platt sheds new light on the early attempts by Western traders and missionaries to "open" China even as China's imperial rulers were struggling to manage their country's decline and Confucian scholars grappled with how to use foreign trade to China's advantage.

From the New York Times best-selling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair.

Antony Beevor has written a completely updated and revised account of one of the most bitter and hard-fought wars of the 20th century. With new material gleaned from Russian archives and numerous other sources, this brisk and accessible audiobook (Spain's number-one best seller for 12 weeks) provides a balanced and penetrating perspective, explaining the tensions that led to this terrible overture to World War II and affording new insights into the war - its causes, course, and consequences.

The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

The dramatic, pulse-pounding story of Harry Truman's first four months in office, when this unlikely president had to take on Germany, Japan, Stalin, and the atomic bomb, with the fate of the world hanging in the balance.

Drink investigates the history of this Jekyll and Hyde of fluids, tracing mankind's love/hate relationship with alcohol from ancient Egypt to present day. Drink further documents the contribution of alcohol to the birth and growth of the United States, taking in the War of Independence, Pennsylvania Whiskey revolt, slave trade, and failed experiment of national Prohibition. Finally, it provides a history of the world's most famous drinks - and drinkers. Packed with trivia and colorful characters, Drink amounts to an intoxicating history of the world.

Many people take math in high school and promptly forget much of it. But math plays a part in all of our lives all of the time, whether we know it or not. In The Joy of x, Steven Strogatz expands on his hit New York Times series to explain the big ideas of math gently and clearly, with wit, and insight.

Based on a decade of research and on interviews with many of Mao's close circle in China who have never talked before, and with virtually everyone outside China who had significant dealings with him, this is the most authoritative biography of Mao ever written.

This magisterial history - sure to become the definitive work on the subject - recasts the Enlightenment as a period not solely consumed with rationale and reason, but rather as a pursuit of practical means to achieve greater human happiness.

Henry at Work invites listeners to rethink how we work today by exploring an aspect of Henry David Thoreau that has often been overlooked: Thoreau the worker. John Kaag and Jonathan van Belle overturn the popular misconception of Thoreau as a navel-gazing recluse who was scornful of work and other mundanities. In fact, Thoreau worked hard—surveying land, running his family's pencil-making business, writing, lecturing, and building his cabin at Walden Pond—and thought intensely about work in its many dimensions.

In Gotham, Edwin G. Burrows and Mike Wallace have produced a monumental work of history, one that ranges from the Indian tribes that settled in and around the island of Manna-hata, to the consolidation of the five boroughs into Greater New York in 1898. It is an epic narrative, a story as vast and as varied as the city it chronicles, and it underscores that the history of New York is the story of our nation. The events and people who crowd this audiobook guarantee that this is no mere local history. It is in fact a portrait of the heart and soul of America....

The rise to global predominance of Western civilization is the single most important historical phenomenon of the past five hundred years. All over the world, an astonishing proportion of people now work for Western-style companies, study at Western-style universities, vote for Western-style governments, take Western medicines, wear Western clothes, and even work Western hours. Yet six hundred years ago the petty kingdoms of Western Europe seemed unlikely to achieve much more than perpetual internecine warfare. It was Ming China or Ottoman Turkey that had the look of world civilizations.

Opium tells the extraordinary and at times harrowing tale of how we arrived at today's crisis, "mak[ing] timely and startling connections among painkillers, politics, finance, and society" (Laurence Bergreen). The story begins with the discovery of poppy artifacts in ancient Mesopotamia, and goes on to explore how Greek physicians and obscure chemists discovered opium's effects and refined its power, how colonial empires marketed it around the world, and eventually how international drug companies developed a range of powerful synthetic opioids that led to an addiction epidemic.

Known to mankind since prehistoric times, opium is arguably the oldest and most widely used narcotic. Opium: A History traces the drug's astounding impact on world culture - from its religious use by prehistoric peoples to its influence on the imaginations of the Romantic writers; from the earliest medical science to the Sino-British opium wars.

Opium has played a dramatic and varied role in human history, inspiring religious veneration, scientific exploration, the bitterest rancor, and the most fanciful ecstasy. Now, authors Jeff Goldberg and Dean Latimer have provided a complete, insightful history of opium. Flowers in the Blood lifts the veil of mystery that has surrounded opium down through the ages.

Throughout human history, certain drinks have done much more than just quench thirst. As Tom Standage relates with authority and charm, six of them have had a surprisingly pervasive influence on the course of history, becoming the defining drink during a pivotal historical period. A History of the World in 6 Glasses tells the story of humanity from the Stone Age to the 21st century through the lens of beer, wine, spirits, coffee, tea, and cola.

In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert, where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?

Tobacco was first cultivated and enjoyed by the indigenous inhabitants of the Americas, who used it for medicinal, religious, and social purposes long before the arrival of Columbus. But when Europeans began to colonize the American continents, it became something else entirely - a cultural touchstone of pleasure and success and a coveted commodity that would transform the world economy forever.

In The Book of Gin, Richard Barnett traces the life of this beguiling spirit, once believed to cause a new kind of drunkenness. In the 18th century, gin-craze debauchery (and class conflict) inspired Hogarth's satirical masterpieces "Gin Lane" and "Beer Street". In the 19th century, gin was drunk by Napoleonic War naval heroes, at lavish gin palaces, and by homesick colonials, who mixed it with their bitter anti-malarial tonics.

We live in an age of addiction, from compulsive gaming and shopping to binge eating and opioid abuse. Sugar can be as habit-forming as cocaine, researchers tell us, and social media apps are hooking our kids. But what can we do to resist temptations that insidiously and deliberately rewire our brains? Nothing, David Courtwright says, unless we understand the history and character of the global enterprises that create and cater to our bad habits.

In A Splendid Exchange, William J. Bernstein tells the extraordinary story of global commerce from its prehistoric origins to the myriad controversies surrounding it today. He transports listeners from ancient sailing ships that brought the silk trade from China to Rome in the second century to the rise and fall of the Portuguese monopoly in spices in the 16th.

Drink investigates the history of this Jekyll and Hyde of fluids, tracing mankind's love/hate relationship with alcohol from ancient Egypt to present day. Drink further documents the contribution of alcohol to the birth and growth of the United States, taking in the War of Independence, Pennsylvania Whiskey revolt, slave trade, and failed experiment of national Prohibition. Finally, it provides a history of the world's most famous drinks - and drinkers. Packed with trivia and colorful characters, Drink amounts to an intoxicating history of the world.

The Wealth and Poverty of Nations is David S. Landes' acclaimed, best-selling exploration of one of the most contentious and hotly debated questions of our time: Why do some nations achieve economic success while others remain mired in poverty? The answer, as Landes definitively illustrates, is a complex interplay of cultural mores and historical circumstance.

The Mexican drug trade has inspired prejudiced narratives of a war between north and south, White and Brown; between noble cops and vicious kingpins, corrupt politicians and powerful cartels. In this first comprehensive history of the trade, historian Benjamin T. Smith tells the real story of how and why this one-peaceful industry turned violent. He uncovers its origins and explains how this illicit business essentially built modern Mexico, affecting everything from agriculture to medicine to economics - and the country’s all-important relationship with the United States.

Why was gin and tonic the cocktail of choice for British colonists in India and Africa? What does Starbucks have to thank for its global domination? What has protected the lives of popes for millennia? Why did Scotland surrender its sovereignty to England? What was George Washington's secret weapon during the American Revolution? The answer to all these questions, and many more, is the mosquito. Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito’s reign through human history.

Ever since Christopher Columbus stepped off the Santa Maria onto what is today San Salvador, in the Bahamas, and announced that he had arrived in the Orient, the Caribbean has been a stage for projected fantasies and competition between world powers. In Empire’s Crossroads, British American historian Carrie Gibson traces the story of this coveted area from the northern rim of South America up to Cuba, and from discovery through colonialism to today, offering a vivid, panoramic view of this complex region and its rich, important history.

How did a simple commodity, once the prized monopoly of kings and princes, become an essential ingredient in the lives of millions, before mutating yet again into the cause of a global health epidemic? Prior to 1600, sugar was a costly luxury, the domain of the rich. But with the rise of the sugar colonies in the New World over the following century, sugar became cheap, ubiquitous, and an everyday necessity. Less than 50 years ago, few people suggested that sugar posed a global health problem.