From “one of the bravest, smartest writers about addiction anywhere” (Johann Hari, New York Times best-selling author) - the untold story of harm reduction, a surprisingly simple idea with enormous power.

Known to mankind since prehistoric times, opium is arguably the oldest and most widely used narcotic. Opium: A History traces the drug's astounding impact on world culture - from its religious use by prehistoric peoples to its influence on the imaginations of the Romantic writers; from the earliest medical science to the Sino-British opium wars.

In Four Lost Cities, acclaimed science journalist Annalee Newitz takes listeners on an entertaining and mind-bending adventure into the deep history of urban life. Investigating across the centuries and around the world, Newitz explores the rise and fall of four ancient cities, each the center of a sophisticated civilization: the Neolithic site of Çatalhöyük in Central Turkey, the Roman vacation town of Pompeii in Italy, the medieval megacity of Angkor in Cambodia, and the indigenous metropolis Cahokia, which stood beside the Mississippi River where East St. Louis is today.

In 1971, Go Ask Alice reinvented the young adult genre with a blistering portrayal of sex, psychosis, and teenage self-destruction. The supposed diary of a middle-class addict, Go Ask Alice terrified adults and cemented LSD's fearsome reputation, fueling support for the War on Drugs. Five million copies later, Go Ask Alice remains a divisive bestseller, outraging censors and earning new fans, all of them drawn by the book's mythic premise: A Real Diary, by Anonymous.

Most of us are clueless when it comes to the physics that makes our modern world so convenient. What's the simple science behind motion sensors, touch screens, and toasters? How do we glide through tolls using an E-ZPass or find our way to new places using GPS? In The Physics of Everyday Things, James Kakalios takes us on an amazing journey into the subatomic marvels that underlie so much of what we use and take for granted.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In this real-life thriller packed with jaw-dropping revelations, award-winning investigative journalist Tom Burgis weaves together stories that reveal a terrifying global web of corruption. Glimpses of this shadowy world have emerged over the years. In Kleptopia, Burgis connects the dots. He follows the dirty money that is flooding the global economy, emboldening dictators, and poisoning democracies. From the Kremlin to Beijing, Harare to Riyadh, Paris to the White House, the trail shows something even more sinister: the thieves are uniting. And the human cost will be great.

In this revealing analysis, Dr. Brodie Ramin tells the story of the opioid crisis, showing us the disease and cure from his perspective as an addiction doctor working on the front lines. We meet his patients, hear from other addiction experts, and learn about the science and medicine of opioid addiction and its treatments. He shows us how addiction can be prevented, how knowledge can reduce stigma, and how epidemics can be beaten.

A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how provocative and challenging its ideas once were - and still are. The Structure of Scientific Revolutions is that kind of book.

Vietnam became the Western world’s most divisive modern conflict, precipitating a battlefield humiliation for France in 1954, then a vastly greater one for the US in 1975. Max Hastings has spent the past three years interviewing scores of participants on both sides, as well as researching a multitude of American and Vietnamese documents and memoirs, to create an epic narrative of an epic struggle. Here are the vivid realities of strife amid jungle and paddies that killed two million people.

At the height of the Holocaust, 25 young inmates of the infamous Auschwitz-Birkenau concentration camp - mainly Jewish women and girls - were selected to design, cut, and sew beautiful fashions for elite Nazi women in a dedicated salon. It was work that they hoped would spare them from the gas chambers. This fashion workshop - called the Upper Tailoring Studio - was established by Hedwig Höss, the camp commandant’s wife, and patronized by the wives of SS guards and officers.

As one of the most potent turning points in the country's modern history, the Opium War has since come to stand for everything that today's China seeks to put behind it. In this dramatic, epic story, award-winning historian Stephen Platt sheds new light on the early attempts by Western traders and missionaries to "open" China even as China's imperial rulers were struggling to manage their country's decline and Confucian scholars grappled with how to use foreign trade to China's advantage.

In this extraordinary work, Beth Macy takes us into the epicenter of a national drama that has unfolded over two decades. From the labs and marketing departments of big pharma to local doctor's offices; wealthy suburbs to distressed small communities in Central Appalachia; from distant cities to once-idyllic farm towns; the spread of opioid addiction follows a tortuous trajectory that illustrates how this crisis has persisted for so long and become so firmly entrenched.

Like the alphabet, the calendar, or the zodiac, the periodic table of the chemical elements has a permanent place in our imagination. But aside from the handful of common ones (iron, carbon, copper, gold), the elements themselves remain wrapped in mystery. We do not know what most of them look like, how they exist in nature, how they got their names, or of what use they are to us.

In late September 2015, Hurricane Joaquin swept past the Bahamas and swallowed a pair of cargo vessels in its destructive path: El Faro, a 790-foot American behemoth with a crew of 33, and the Minouche, a 230-foot freighter with a dozen sailors aboard. From the parallel stories of these ships and their final journeys, Tristram Korten weaves a remarkable tale of two veteran sea captains from very different worlds, the harrowing ordeals of their desperate crews, and the Coast Guard’s extraordinary battle against a storm that defied prediction.

Poppy tears, opium, heroin, fentanyl: humankind has been in thrall to the ‘Milk of Paradise’ for millennia. The latex of papaver somniferum is a bringer of sleep, of pleasurable lethargy, of relief from pain - and hugely addictive. A commodity without rival, it is renewable, easy to extract, transport and refine, and subject to an insatiable global demand. No other substance in the world is as simple to produce or as profitable. It is the basis of a gargantuan industry built upon a shady underworld, but ultimately it is a farm-gate material that lives many lives ....

Opium has played a dramatic and varied role in human history, inspiring religious veneration, scientific exploration, the bitterest rancor, and the most fanciful ecstasy. Now, authors Jeff Goldberg and Dean Latimer have provided a complete, insightful history of opium. Flowers in the Blood lifts the veil of mystery that has surrounded opium down through the ages.

Known to mankind since prehistoric times, opium is arguably the oldest and most widely used narcotic. Opium: A History traces the drug's astounding impact on world culture - from its religious use by prehistoric peoples to its influence on the imaginations of the Romantic writers; from the earliest medical science to the Sino-British opium wars.

Martin A. Lee traces the dramatic social history of marijuana, from its origins to its emergence in the 1960s as a defining force in a culture war that has never ceased. Lee describes how the illicit marijuana subculture overcame government opposition and morphed into a dynamic, multibillion-dollar industry. Colorful, illuminating, and at times irreverent, this is a fascinating listen for recreational users and patients, students and doctors, musicians and accountants, Baby Boomers and their kids, and anyone who has ever wondered about the secret life of this ubiquitous herb.

We live in an age of addiction, from compulsive gaming and shopping to binge eating and opioid abuse. Sugar can be as habit-forming as cocaine, researchers tell us, and social media apps are hooking our kids. But what can we do to resist temptations that insidiously and deliberately rewire our brains? Nothing, David Courtwright says, unless we understand the history and character of the global enterprises that create and cater to our bad habits.

Past antidrug campaigns actually encouraged drug use. A few years ago, America stopped dropping acid altogether. The meth epidemic peaked a long, long time ago. NAFTA opened the border and created a bonanza for cocaine and meth traffickers just as President Clinton knew it would. President Reagan may have inadvertently caused the crack epidemic. Kids today are doing fewer illegal drugs than kids from any time in the recent past, and for a surprising reason.

Shooting Up: A Short History of Drugs and War examines how intoxicants have been put to the service of states, empires, and their armies throughout history. Since the beginning of organized combat, armed forces have prescribed drugs to their members for two general purposes: to enhance performance during combat and to counter the trauma of killing and witnessing violence after it is over.

Tobacco was first cultivated and enjoyed by the indigenous inhabitants of the Americas, who used it for medicinal, religious, and social purposes long before the arrival of Columbus. But when Europeans began to colonize the American continents, it became something else entirely - a cultural touchstone of pleasure and success and a coveted commodity that would transform the world economy forever.

Once literally demonized as "the Devil's lettuce" and linked to all manner of deviant behavior by the establishment's shameless antimarijuana propaganda campaigns, Cannabis sativa has lately been enjoying a long-overdue Renaissance. So now that the squares at long last seem ready to rethink pot's place in polite society, how, exactly, can members of this vibrant, innovative, life-affirming culture proudly and properly emerge from the underground - without forgetting our roots or losing our cool?

Throughout human history, certain drinks have done much more than just quench thirst. As Tom Standage relates with authority and charm, six of them have had a surprisingly pervasive influence on the course of history, becoming the defining drink during a pivotal historical period. A History of the World in 6 Glasses tells the story of humanity from the Stone Age to the 21st century through the lens of beer, wine, spirits, coffee, tea, and cola.

In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert, where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs but the corrupting of medicine and public institutions that let the opioid makers get away with it.

Guns, germs, and steel might have transformed us from hunter-gatherers into modern man, but booze, sex, trash talk, and tripping built our civilization. Cracked editor Robert Evans brings his signature dogged research and lively insight to uncover the many and magnificent ways vice has influenced history, from the prostitute-turned-empress who scored a major victory for women's rights to the beer that helped create - and destroy - South America's first empire.

In Saving Normal, Allen Frances, one of the world's most influential psychiatrists, warns that mislabeling everyday problems as mental illness has shocking implications for individuals and society: Stigmatizing a healthy person as mentally ill leads to unnecessary, harmful medications, the narrowing of horizons, misallocation of medical resources, and draining of the budgets of families and the nation.