Traumatized by the bombing of Dresden at the time he had been imprisoned, Pilgrim drifts through all events and history, sometimes deeply implicated, sometimes a witness. He is surrounded by Vonnegut's usual large cast of continuing characters (notably here the hack science fiction writer Kilgore Trout and the alien Tralfamadorians, who oversee his life and remind him constantly that there is no causation, no order, no motive to existence).

In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson's Research, the world's leading nonprofit funder of PD science.

In the summer after graduating from college, Suleika Jaouad was preparing, as they say in commencement speeches, to enter “the real world”. She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone. It started with an itch - first on her feet, then up her legs, like a thousand invisible mosquito bites. Then a trip to the doctor and, a few weeks shy of her 23rd birthday, a diagnosis: leukemia, with a 35 percent chance of survival.

When her earliest childhood friend is diagnosed with a terminal illness, Becker sets off on a quest to immerse herself in what it means to be mortal. Can we live our lives more fully knowing some day we will die? With a keen eye toward that which makes life worth living, interfaith minister, mom, and perpetual seeker Barbara Becker recounts stories where life and death intersect in unexpected ways.

It’s hard to give up on the feeling that the life you really want is just out of reach. A beach body by summer. A trip to Disneyland around the corner. A promotion on the horizon. Everyone wants to believe that they are headed toward good, better, best. But what happens when the life you hoped for is put on hold indefinitely?

Actor Jim Beaver (Supernatural, Deadwood, Justified) and his wife Cecily Adams (Star Trek: Deep Space Nine's Moogie) were at the peaks of their careers and happily raising a beautiful two-year old daughter, Madeline. Then tragedy struck, not once, but twice. What followed was laid down by Jim in a moving, poignant, and uplifting journal of the following year, a year filled with heartbreak as well as enormous gifts and invaluable lessons, not just for Jim and his family but for listeners who traveled along with him on his journey.

Dr. W. Lee Warren, a practicing brain surgeon, assumed he knew most outcomes for people with glioblastoma, head injuries, and other health-care problems. Yet even as he tried to give patients hope, his own heart would sink as he realized, I've seen the end of you. But it became far more personal when the acclaimed doctor experienced an unimaginable family tragedy. That's when he reached the end of himself. Gripping medical stories serve as the backdrop for a raw, honest look at how we can remain on solid ground when everything goes wrong.

Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive.

When Steph Catudal met her husband Rivs, she thought that the love, stability, and warmth she shared with her husband had finally dispelled her pent-up anger and grief over the loss of her father and her faith. But when Rivs became ill and was put into coma at the height of the pandemic, the painful memories of her childhood—watching her father die of cancer—came flooding back.

Tumors, injuries, ruptured vascular malformations—there is almost no such thing as a non-urgent brain surgery when it comes to kids. For a pediatric neurosurgeon working in the medical minefield of the brain—in which a single millimeter in every direction governs something that makes us essentially human—every day presents the challenge, and the opportunity, to give a new lease on life to a child for whom nothing is yet fully determined and all possibilities still exist.

When you are told that you have leukemia, your world stops. Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes listeners on the journey that patient and doctor travel together.

After being diagnosed in her early forties with metastatic melanoma - a "rapidly fatal" form of cancer - journalist and mother of two Mary Elizabeth Williams finds herself in a race against the clock. She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own - with very different results.

In this revelatory memoir, doctor Cynthia Li shares the truth other doctors don’t always understand and often won’t share if they do - that chronic illness is complicated, and that treatment is not just a matter of test results and prescriptions but requires a more comprehensive approach. By sharing her own struggle with a disabling autoimmune crisis, which forced her to question her own conventional medical training and embrace the integrative principles of functional medicine, Li reveals the insider knowledge sufferers need to truly begin healing - mind, body, and spirit.

When her earliest childhood friend is diagnosed with a terminal illness, Becker sets off on a quest to immerse herself in what it means to be mortal. Can we live our lives more fully knowing some day we will die? With a keen eye toward that which makes life worth living, interfaith minister, mom, and perpetual seeker Barbara Becker recounts stories where life and death intersect in unexpected ways.

When their only child was diagnosed with cystic fibrosis (CF) at the age of two, Maryanne O'Hara and her husband were told that Caitlin could live a long life or be dead in a matter of months. Thirty-one years later, Caitlin lost her battle with this devastating disease following an excruciating two-year wait on the transplant list and a last-minute race to locate a pair of healthy lungs. The sudden spiral of events left Maryanne in an existential crisis, searching to find an answer to the eternal question: Why we are here?

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

You get ready to die the way you get ready for a trip. Start by realizing you don't know the way. Listen to a few travel guides. Study the language, look at maps, gather equipment. Let yourself imagine what it will be like. Pack your bags. This book is one of those travel guides - a guide to preparing for your own death and the deaths of people close to you. The fact of death is hard to believe. Sallie Tisdale explores our fears and all the ways death and talking about death make us uncomfortable - but she also explores its intimacies and joys.

Like so many of us, award-winning writer Katy Butler always assumed her aging parents would experience healthy, active retirements before dying peacefully at home. Then her father suffered a stroke that left him incapable of easily finishing a sentence or showering without assistance. Her mother was thrust into full-time caregiving, and Katy became one of the 24 million Americans who help care for aging parents. In an effort to correct a minor and non - life threatening heart arrhythmia, doctors outfitted her father with a pacemaker.

Dr. Kathy Magliato is one of fewer than a dozen female heart surgeons practicing in the world today. She is also a member of an even more exclusive group - those surgeons who perform heart transplants. Healing Hearts is the story of the making of a surgeon who also calls herself a wife and mother.

In the late 1990s, a young physician in Albuquerque, New Mexico, published a stunning memoir of his experiences in the highly charged world of the ER. Presented in a series of powerful, poetic vignettes, The Blood of Strangers became an instant classic. Now, over two decades later, Dr. Frank Huyler delivers another dispatch from the trenches—this time from the perspective of middle age. In portraits visceral, haunting, sometimes surreal, Huyler reveals the gritty reality of medicine practiced on the razor’s edge between life and death.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Forensic pathologist Janis Amatuzio first began recording the stories told to her by patients, police officers, and other doctors because she felt that no one spoke for the dead. She believed the real experience of death, namely the spiritual and otherworldly experiences of those near death and their loved ones, was ignored by the medical professionals, who thought of death as simply the cessation of breath. She knew there was more.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

When Amy B. Scher was struck with undiagnosed late-stage, chronic Lyme disease, the best physicians in America labeled her condition incurable and potentially terminal. Deteriorating rapidly, she went on a search to save her own life - from the top experts in Los Angeles and the world-renowned Mayo Clinic in Minneapolis to a state-of-the-art hospital in Chicago. After exhausting all of her options in the US, she discovered a possible cure - but it was highly experimental, available only in India, and had as much of a probability of killing her as it did of curing her.

Already Here tells of the death of Leo Galland's son, Christopher, at age 22; the direct visual evidence Christopher showed Leo that our souls do go on; and the communications from Christopher's spirit that changed Leo's understanding of life and its meaning. In life, Christopher was a brain-damaged special-needs child who challenged everyone he knew with unpredictable behavior and uncanny insights. After his death, he revealed to Leo the real purpose of his life, as a spiritual guide who taught others by confounding their assumptions and expectations.

As if juggling a life with half-a-dozen kids, including triplets, isn’t enough, Steve Tate receives the life-altering news that one of his triplets, Hayes, has been diagnosed with brain cancer. The once-star collegiate football player finds himself fighting for his son’s life. This memoir takes you through the various challenges he faced raising a family of six kids and balancing a career, all while his son battled the odds. Both Steve and his high-school sweetheart, Savanna, found hope and happiness through the example of their 20-month-old son Hayes.

Crushed between a truck and a tree, Simon and his wife were both pronounced dead at the scene of a horrific car accident. Enduring a broken skull, jaw, arms, clavicle and pelvis, followed by a coma, Simon lives to tell his remarkable journey from tragedy to triumph.

An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in the career of a distinguished physi­cian. In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today.