In 1954, researchers at the newly formed National Institute of Mental Health set out to study the genetics of schizophrenia. When they got word that four 24-year-old identical quadruplets in Lansing, Michigan, had all been diagnosed with the mental illness, they could hardly believe their ears. Here was incontrovertible proof of hereditary transmission and, thus, a chance to bring international fame to their fledgling institution.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

Growing up in the 1960s in the suburbs of Chicago, Meg Kissinger’s family seemed to live a charmed life. With eight kids and two loving parents, the Kissingers radiated a warm, boisterous energy. Whether they were spending summer days on the shores of Lake Michigan, barreling down the ski slopes, or navigating the trials of their Catholic school, the Kissingers always knew how to live large and play hard. But behind closed doors, a harsher reality was unfolding.

Abandoned at 10 years old by a mother who chose her drug-addicted, abusive boyfriend, Danielle was raised by grandparents who thought their child-rearing days had ended in the 1960s. She grew up Black, weird, and overwhelmingly uncool in a mostly white neighborhood in upstate New York, which created its own identity crises.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

After years of hiding her addiction from everyone—stockpiling pills in her Louboutins and elaborately scheduling her withdrawals between PTA meetings, baby showers, and tennis matches—Laura Cathcart Robbins is running out of places to hide. She has learned the hard way that even her high-profile marriage and Hollywood lifestyle can’t protect her from the pain she’s keeping bottled up inside. Facing divorce, the possibility of a custody battle, and the insistent voice of internalized racism that nags at her as a Black woman in a white world, Laura wonders just how much more she can take.

Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts. In his seminal new audiobook, The Disordered Mind, Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain?

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

For centuries, works of art have been stolen in countless ways from all over the world, but no one has been quite as successful at it as the master thief Stéphane Breitwieser. Carrying out more than two hundred heists over nearly eight years—in museums and cathedrals all over Europe—Breitwieser, along with his girlfriend who worked as his lookout, stole more than three hundred objects, until it all fell apart in spectacular fashion.

As a Yale School of Medicine physician, the New York Times best-selling author of Every Patient Tells a Story, and an inspiration and adviser for the hit Fox TV drama, House, M.D., Lisa Sanders has seen it all. And yet, she is often confounded by the cases she describes in her column: unexpected collections of symptoms that she and other physicians struggle to diagnose. Dr. Sanders shows how making the right diagnosis requires expertise, painstaking procedure, and sometimes a little luck.

New York Times bestselling author Laurence Leamer reveals the complex web of relationships and scandalous true stories behind Truman Capote's never-published final novel, Answered Prayers—the dark secrets, tragic glamour, and Capote's ultimate betrayal of the group of female friends he called his "swans."

Why we think it’s a great listen: You thought he was a stodgy scientist with funny hair, but Isaacson and Hermann reveal an eloquent, intense, and selfless human being who not only shaped science with his theories, but politics and world events in the 20th century as well. Based on the newly released personal letters of Albert Einstein, Walter Isaacson explores how an imaginative, impertinent patent clerk became the mind reader of the creator of the cosmos.

In his landmark best seller The Tipping Point, Malcolm Gladwell redefined how we understand the world around us. Now, in Blink, he revolutionizes the way we understand the world within. Blink is a book about how we think without thinking, about choices that seem to be made in an instant, in the blink of an eye, that actually aren't as simple as they seem. Why are some people brilliant decision makers, while others are consistently inept?

Barbara Butcher was early in her recovery from alcoholism when she found an unexpected lifeline: a job at the Medical Examiner’s Office in New York City. The second woman ever hired for the role of Death Investigator in Manhattan, she was the first to last more than three months. The work was gritty, demanding, morbid, and sometimes dangerous—and she loved it. In What the Dead Know, she writes with the kind of New York attitude and bravado you might expect from decades in the field, investigating more than 5,500 death scenes, 680 of which were homicides.

In 1999, Clark Elliott suffered a concussion when his car was rear-ended. Overnight his life changed from that of a rising professor with a research career in artificial intelligence to a humbled man struggling to get through a single day. At times he couldn't walk across a room, or even name his five children. Doctors told him he would never fully recover. After eight years, the cognitive demands of his job, and of being a single parent, finally became more than he could manage.

From the best-selling author of Gratitude and On the Move, a final volume of essays that showcase Sacks's broad range of interests - from his passion for ferns, swimming, and horsetails, to his final case histories exploring schizophrenia, dementia, and Alzheimer's.

Permanent Present Tense tells the incredible story of Henry Gustav Molaison, known only as H. M. until his death in 2008. In 1953, at the age of 27, Molaison underwent a dangerous "psychosurgical" procedure intended to alleviate his debilitating epilepsy. The surgery went horribly wrong, and when Molaison awoke he was unable to store new experiences. For the rest of his life, he would be trapped in the moment. But Molaison’s tragedy would prove a gift to humanity.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

One day in 2002 the 50-year old body of former Pittsburgh Steeler and hall of famer Mike Webster was laid on a cold table in front of pathologist Dr. Bennet Omalu. Webster's body looked to Omalu like the body of a much older man, and the circumstances of his behavior prior to his death were clouded in mystery. But when Omalu cut into Webster's brain, it appeared to be normal. Something didn't add up.

Professor Richard Wiseman is clear about one thing: paranormal phenomena don't exist. But in the same way that the science of space travel transforms our everyday lives, so research into telepathy, fortune-telling and out of body experiences produces remarkable insights into our brains, behaviour and beliefs.

The noted research psychiatrist explores how life's disappointments and difficulties provide us with the lessons we need to become better, bigger, and more resilient human beings. Adversity is an irreducible fact of life. Although we can and should learn from all experiences, both positive and negative best-selling author Dr. Norman E. Rosenthal believes that adversity is by far the best teacher most of us will ever encounter.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program, and as humanity is tantalizingly close to eradicating polio worldwide, comes this unforgettable chronicle. Salk's work was an unparalleled achievement, and it makes for a magnificent listen.

Every 69 seconds, someone is diagnosed with Alzheimer's disease. Of the top 10 killers, it is the only disease for which there is no cure or treatment. For most people, there is nothing that they can do to fight back. But one family is doing all they can. The DeMoe family has the most devastating form of the disease that there is: early onset Alzheimer's, an inherited genetic mutation that causes the disease in 100 percent of cases, and has a 50 percent chance of being passed onto the next generation.

A first-person account of Jim Tucker's experiences with a number of extraordinary children with memories of past lives, Return to Life focuses mostly on American cases, presenting each family's story and describing his investigation. His goal is to determine what happened-what the child has said, how the parents have reacted, whether the child's statements match the life of a particular deceased person, and whether the child could have learned such information through normal means.

G. Wayne Miller has dramatically and meticulously reconstructed an amazing true story: how a group of renegade Minnesota surgeons, led by Dr. Walt Lillehei, made medical history by becoming the first doctors to operate deep inside the human heart.

Crushed between a truck and a tree, Simon and his wife were both pronounced dead at the scene of a horrific car accident. Enduring a broken skull, jaw, arms, clavicle and pelvis, followed by a coma, Simon lives to tell his remarkable journey from tragedy to triumph.

Important and provocative, The Undead examines why even with the tools of advanced technology, what we think of as life and death, consciousness and nonconsciousness, is not exactly clear - and how this problem has been further complicated by the business of organ harvesting.

In 1954, researchers at the newly formed National Institute of Mental Health set out to study the genetics of schizophrenia. When they got word that four 24-year-old identical quadruplets in Lansing, Michigan, had all been diagnosed with the mental illness, they could hardly believe their ears. Here was incontrovertible proof of hereditary transmission and, thus, a chance to bring international fame to their fledgling institution.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their 12 children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the 10 Galvin boys, one after another, were diagnosed as schizophrenic.

Moving, harrowing, and ultimately uplifting, Lori Schiller's memoir is a classic testimony to the ravages of mental illness and the power of perseverance and courage. At 17, Lori Schiller was the perfect child - the only daughter of an affluent, close-knit family. Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia.

David Oshinsky, whose last book, Polio: An American Story, was awarded a Pulitzer Prize, chronicles the history of America's oldest hospital and in so doing also charts the rise of New York to the nation's preeminent city, the path of American medicine from butchery and quackery to a professional and scientific endeavor, and the growth of a civic institution.

Permanent Present Tense tells the incredible story of Henry Gustav Molaison, known only as H. M. until his death in 2008. In 1953, at the age of 27, Molaison underwent a dangerous "psychosurgical" procedure intended to alleviate his debilitating epilepsy. The surgery went horribly wrong, and when Molaison awoke he was unable to store new experiences. For the rest of his life, he would be trapped in the moment. But Molaison’s tragedy would prove a gift to humanity.

Professor of psychiatry Elyn R. Saks writes about her struggle with schizophrenia in this unflinching account of her mental illness. In The Center Cannot Hold, Saks draws readers into a nightmare world of medications, a misguided health-care system, and social stigmas. But she would not be defeated. With a strength and force of will that most can only imagine, Saks reclaimed her life and went on to achieve great success.

Vince Granata remembers standing in front of his suburban home in Connecticut the day his mother and father returned from the hospital with his three new siblings in tow. He had just finished scrawling their names in orange chalk on the driveway: Christopher, Timothy, and Elizabeth. Twenty-three years later, Vince was a thousand miles away when he received the news that would change his life - his younger brother, Tim, propelled by unchecked schizophrenia, had killed their mother in their childhood home.

Ruth Wariner was the 39th of her father's 42 children. Growing up on a farm in rural Mexico, where authorities turned a blind eye to the practices of her community, Ruth lives in a ramshackle house without indoor plumbing or electricity. At church, preachers teach that God will punish the wicked by destroying the world and that women can ascend to heaven only by entering into polygamous marriages and giving birth to as many children as possible.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.