From the celebrated neurobiologist and primatologist, a landmark, genre-defining examination of human behavior, both good and bad, and an answer to the question: Why do we do the things we do? Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: He starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.

Robert Sapolsky’s Behave, his now classic account of why humans do good and why they do bad, pointed toward an unsettling conclusion: We may not grasp the precise marriage of nature and nurture that creates the physics and chemistry at the base of human behavior, but that doesn’t mean it doesn’t exist. Now, in Determined, Sapolsky takes his argument all the way, mounting a brilliant (and in his inimitable way, delightful) full-frontal assault on the pleasant fantasy that there is some separate self telling our biology what to do.

A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings listeners from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the 20th century: the search for the biological basis of memory. Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind - a combination of cognitive psychology, neuroscience, and molecular biology - with his own personal quest to understand memory.

Are art and science separated by an unbridgeable divide? Can they find common ground? In this book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism - the distillation of larger scientific or aesthetic concepts into smaller, more tractable components - has been used by scientists and artists alike to pursue their respective truths.

A brilliant book by Nobel Prize winner Eric R. Kandel, The Age of Insight takes us to Vienna 1900, where leaders in science, medicine, and art began a revolution that changed forever how we think about the human mind - our conscious and unconscious thoughts and emotions - and how mind and brain relate to art.

Since publication in 1983, Surviving Schizophrenia has become the standard reference book on the disease and has helped thousands of patients, their families, and mental health professionals. In clear language, this much-praised and important book describes the nature, causes, symptoms, treatment, and course of schizophrenia and also explores living with it from both the patient's and the family's point of view. This new, completely updated sixth edition includes the latest research findings on what causes the disease, as well as information about the newest drugs for treatment.

The Strange Order of Things is a pathbreaking investigation into homeostasis, the condition that regulates human physiology within the range that makes possible not only the survival but also the flourishing of life. Antonio Damasio makes clear that we descend biologically, psychologically, and even socially from a long lineage that begins with single living cells; that our minds and cultures are linked by an invisible thread to the ways and means of ancient unicellular life and other primitive life-forms.

The science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology. Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose research overturns the long-standing belief that emotions are automatic, universal, and hardwired in different brain regions. Instead, Barrett shows, we construct each instance of emotion through a unique interplay of brain, body, and culture.

For Mark Solms, one of the boldest thinkers in contemporary neuroscience, discovering how consciousness comes about has been a lifetime's quest. Scientists consider it the "hard problem" because it seems an impossible task to understand why we feel a subjective sense of self and how it arises in the brain. Venturing into the elementary physics of life, Solms has now arrived at an astonishing answer. In The Hidden Spring, he brings forward his discovery in accessible language and graspable analogies.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

In The Brain That Changes Itself, Norman Doidge described the most important breakthrough in our understanding of the brain in 400 years: the discovery that the brain can change its own structure and function in response to mental experience - what we call neuroplasticity. His revolutionary new book shows, for the first time, how the amazing process of neuroplastic healing really works. It describes natural, noninvasive avenues into the brain provided by the forms of energy around us.

In The Molecule of More: How a Single Chemical in Your Brain Drives Love, Sex, and Creativity—and will Determine the Fate of the Human Race, George Washington University professor and psychiatrist Daniel Z. Lieberman, MD, and Georgetown University lecturer Michael E. Long present a potentially life-changing proposal: Much of human life has an unconsidered component that explains an array of behaviors previously thought to be unrelated, including why winners cheat, why geniuses often suffer with mental illness, why nearly all diets fail, and more.

An intimate, moving book written with the immediacy and directness of one who still struggles with the effects of mental and chronic illness, The Collected Schizophrenias cuts right to the core. Schizophrenia is not a single unifying diagnosis, and Esmé Weijun Wang writes not just to her fellow members of the “collected schizophrenias” but to those who wish to understand it as well.

In this sparkling and provocative new book, the renowned neuroscientist David Eagleman navigates the depths of the subconscious brain to illuminate surprising mysteries. Taking in brain damage, plane spotting, dating, drugs, beauty, infidelity, synesthesia, criminal law, artificial intelligence, and visual illusions, Incognito is a thrilling subsurface exploration of the mind and all its contradictions.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

John Ratey, best-selling author and clinical professor of psychiatry at Harvard Medical School, lucidly explains the human brain's workings, and paves the way for a better understanding of how the brain affects who we are. Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior. By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.

You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones... to which this book says: Pure nonsense.

A leading brain scientist's look at the neurobiology of pleasure-and how pleasures can become addictions. Whether eating, taking drugs, engaging in sex, or doing good deeds, the pursuit of pleasure is a central drive of the human animal. In The Compass of Pleasure Johns Hopkins neuroscientist David J. Linden explains how pleasure affects us at the most fundamental level: in our brain.

Sleep. Memory. Pleasure. Fear. Language. We experience these things every day, but how do our brains create them? Your Brain, Explained is a personal tour around your gray matter. Neuroscientist Marc Dingman gives you a crash course in how your brain works and explains the latest research on the brain functions that affect you on a daily basis. You'll also discover what happens when the brain doesn't work the way it should, causing problems such as insomnia, ADHD, depression, or addiction.

A brilliant book by Nobel Prize winner Eric R. Kandel, The Age of Insight takes us to Vienna 1900, where leaders in science, medicine, and art began a revolution that changed forever how we think about the human mind - our conscious and unconscious thoughts and emotions - and how mind and brain relate to art.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

Why are some people so quick to recover from a setback while others wallow in despair? Why are some people so highly attuned to others that they seem psychic, while other people put both feet in it over and over again? Why are some people always up and others always down? In this hotly anticipated book, award-winning, pioneering neuroscientist Richard J. Davidson answers these questions by offering an entirely new model of our emotions - their origins, their power, and their malleability.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

In Do Zombies Dream of Undead Sheep?, neuroscientists and zombie enthusiasts Timothy Verstynen and Bradley Voytek apply their neuro-know-how to dissect the puzzle of what has happened to the zombie brain to make the undead act differently than their human prey. Combining tongue-in-cheek analysis with modern neuroscientific principles, Verstynen and Voytek show how zombism can be understood in terms of current knowledge regarding how the brain works.

The memoir of a neuroscientist whose research led him to a bizarre personal discovery, James Fallon had spent an entire career studying how our brains affect our behavior when his research suddenly turned personal. While studying brain scans of several family members, he discovered that one perfectly matched a pattern he’d found in the brains of serial killers. This meant one of two things: Either his family’s scans had been mixed up with those of felons or someone in his family was a psychopath.

Mr. A. was admitted to Dr. Joel Gold’s inpatient unit at Bellevue Hospital in 2002. He was, he said, being filmed constantly, and his life was being broadcast around the world "like The Truman Show" - the 1998 film depicting a man who is unknowingly living out his life as the star of a popular soap opera. Over the next few years, Gold saw a number of patients suffering from what he and his brother, Dr. Ian Gold, began calling the "Truman Show Delusion," launching them on a quest to understand the nature of this particular phenomenon and the nature of madness itself.

In Drugged, Miller takes listeners on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture. Drugged brims with surprises, revealing the fact that antidepressant drugs evolved from rocket fuel, highlighting the role of hallucinogens in the history of religion, and asking whether Prozac can help depressed cats. Entertaining and authoritative, Drugged is a truly fascinating book.

What causes a child to grow up gay or straight? In this book, neuroscientist Simon LeVay summarizes a wealth of scientific evidence that points to one inescapable conclusion: Sexual orientation results primarily from an interaction between genes, sex hormones, and the cells of the developing body and brain. LeVay helped create this field in 1991 with a much-publicized study in Science, where he reported on a difference in the brain structure between gay and straight men. Since then, an entire scientific discipline has sprung up around the quest for a biological explanation of sexual orientation. In this book, LeVay provides a clear explanation of where the science stands today, taking the reader on a whirlwind tour of laboratories that specialize in genetics, endocrinology, neuroscience, cognitive psychology, evolutionary psychology, and family demographics. He describes, for instance, how researchers have manipulated the sex hormone levels of animals during development, causing them to mate preferentially with animals of their own gender. LeVay also reports on the prevalence of homosexual behavior among wild animals, ranging from Graylag geese to the Bonobo chimpanzee.

Does religious experience come from God, or is it just the random firing of neurons in the brain? Drawing on brain research on Carmelite nuns that has attracted major media attention and provocative new research in near-death experiences, The Spiritual Brain proves that genuine, life-changing spiritual events can be documented. The authors make a convincing case for what many in science are loathe to consider: that it is God who creates our spiritual experiences, not the brain.

Sleep is one of the most important but least understood aspects of our life, wellness, and longevity. Until very recently, science had no answer to the question of why we sleep, or what good it served, or why we suffer such devastating health consequences when we don't sleep. Compared to the other basic drives in life - eating, drinking, and reproducing - the purpose of sleep remained elusive.

A deft mixture of memoir and history, modern biology and behavior, In Search of Memory brings listeners from Kandel's childhood in Nazi-occupied Vienna to the forefront of one of the great scientific endeavors of the 20th century: the search for the biological basis of memory. Nobel Prize winner Eric R. Kandel intertwines the intellectual history of the powerful new science of the mind - a combination of cognitive psychology, neuroscience, and molecular biology - with his own personal quest to understand memory.

A brilliant book by Nobel Prize winner Eric R. Kandel, The Age of Insight takes us to Vienna 1900, where leaders in science, medicine, and art began a revolution that changed forever how we think about the human mind - our conscious and unconscious thoughts and emotions - and how mind and brain relate to art.

Are art and science separated by an unbridgeable divide? Can they find common ground? In this book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism - the distillation of larger scientific or aesthetic concepts into smaller, more tractable components - has been used by scientists and artists alike to pursue their respective truths.

This “incredibly captivating” (Siddhartha Mukherjee, author of The Emperor of All Maladies) portrait of schizophrenia, the most malignant and mysterious mental illness, by renowned psychiatrist Jeffrey Lieberman, interweaves cultural and scientific history with dramatic patient profiles and clinical experiences to impart a revolutionary message of hope. For the first time in history, we can effectively treat schizophrenia, limiting its disabling effects—and we’re on the verge of being able to prevent the disease’s onset entirely.

In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared.

New York Times-best-selling author Ron Powers offers a searching, richly researched narrative of the social history of mental illness in America paired with the deeply personal story of his two sons' battles with schizophrenia. From the centuries of torture of "lunatiks" at Bedlam Asylum to the infamous eugenics era to the follies of the anti-psychiatry movement to the current landscape in which too many families struggle alone to manage afflicted love ones, Powers limns our fears and myths about mental illness and the fractured public policies that have resulted.

The concept of personality disorders rose to prominence in the early twentieth century and has consistently caused controversy among psychiatrists, psychologists, and social scientists. In Personality Disorders, Allan V. Horwitz traces the evolution of defining these disorders and the historical dilemmas of attempting to mold them into traditional medical conceptions of disorder.

Since its first publication in 1983, Surviving Schizophrenia has become the standard reference book on the disease that has helped thousands of patients, their families, and mental health professionals alike. In clear language, this much-praised and important book describes the nature, causes, symptoms, treatment, and course of schizophrenia, and explores living with it from both the patient’s and the family’s point of view.

"Correlation does not imply causation". This mantra has been invoked by scientists for decades and has led to a virtual prohibition on causal talk. But today, that taboo is dead. The causal revolution, sparked by Judea Pearl and his colleagues, has cut through a century of confusion and placed causality - the study of cause and effect - on a firm scientific basis.

Vince Granata remembers standing in front of his suburban home in Connecticut the day his mother and father returned from the hospital with his three new siblings in tow. He had just finished scrawling their names in orange chalk on the driveway: Christopher, Timothy, and Elizabeth. Twenty-three years later, Vince was a thousand miles away when he received the news that would change his life - his younger brother, Tim, propelled by unchecked schizophrenia, had killed their mother in their childhood home.