From the masters of storytelling-meets-science, Patient Zero tells the long and fascinating history of disease outbreaks—how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors’ lively style, chapters include gripping medical stories about a particular disease or virus—smallpox, Bubonic plague, polio, HIV—that combine “Patient Zero” narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

According to the accepted narrative of progress, humans have thrived thanks to their brains and brawn, collectively bending the arc of history. But in this revelatory book, Professor Jonathan Kennedy argues that the myth of human exceptionalism overstates the role that we play in social and political change. Instead, it is the humble microbe that wins wars and topples empires.

The Pax Romana has long been shorthand for the empire’s golden age. Stretching from Caledonia to Arabia, Rome ruled over a quarter of the world’s population. It was the wealthiest and most formidable state in the history of humankind. Pax is a captivating narrative history of Rome at the height of its power. From the gilded capital to realms beyond the frontier, historian Tom Holland shows ancient Rome in all its glory

Homer’s Iliad and Odyssey are unquestionably two of the greatest epic masterpieces in Western literature. Though more than 2,700 years old, their stories of brave heroics, capricious gods, and towering human emotions are vividly timeless. The Iliad can justly be called the world’s greatest war epic. The terrible and long-drawn-out siege of Troy remains one of the classic campaigns. The Odyssey chronicles the many trials and adventures Odysseus must pass through on his long journey home from the Trojan wars to his beloved wife.

Global warming is one of the greatest dangers mankind faces today. Even as temperatures increase, sea levels rise, and natural disasters escalate, our current environmental crisis feels difficult to predict and understand. But climate change and its effects on us are not new. In a bold narrative that spans centuries and continents, Peter Frankopan argues that nature has always played a fundamental role in the writing of history.

Why was gin and tonic the cocktail of choice for British colonists in India and Africa? What does Starbucks have to thank for its global domination? What has protected the lives of popes for millennia? Why did Scotland surrender its sovereignty to England? What was George Washington's secret weapon during the American Revolution? The answer to all these questions, and many more, is the mosquito. Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito’s reign through human history.

Breathless is story of SARs-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a “forever virus,” destined to circulate among humans and bedevil us endlessly, in one variant form or another.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

The seventeenth century was a revolutionary age for the English. It started as they suddenly found themselves ruled by a Scotsman, and it ended in the shadow of an invasion by the Dutch. Under James I, England suffered terrorism and witch panics. Under his son Charles, state and society collapsed into civil war, to be followed by an army coup and regicide. For a short time—for the only time in history—England was a republic. There were bitter struggles over faith and Parliament asserted itself like never before. There were no boundaries to politics.

Drawn from historical records and current news headlines, A Taste for Poison weaves together the tales of spurned lovers, shady scientists, medical professionals, and political assassins to show how the precise systems of the body can be impaired to lethal effect through the use of poison. From the deadly origins of the gin and tonic cocktail to the arsenic-laced wallpaper in Napoleon’s bedroom, A Taste for Poison leads listeners on a fascinating tour of the intricate, complex systems that keep us alive - or don’t.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Johannes Krause is the director of the Max Planck Institute for Evolutionary Anthropology and a brilliant pioneer in the field of archaeogenetics - archaeology augmented by DNA sequencing technology - which has allowed scientists to reconstruct human history reaching back hundreds of thousands of years before recorded time. In this surprising account, Krause and journalist Thomas Trappe rewrite a fascinating chapter of this history, the peopling of Europe, that takes us from the Neanderthals and Denisovans to the present.

The Great War of 1914-1918 burst on the European scene with a brutality to mankind not yet witnessed by the civilized world. Modern warfare was no longer the stuff of chivalry and honor; it was a mutilative, deadly, and humbling exercise to wipe out the very presence of humanity. Suddenly, thousands upon thousands of maimed, beaten, and bleeding men surged into aid stations and hospitals with injuries unimaginable in their scope and destruction. Doctors scrambled to find some way to salvage not only life but limb.

Having done field work in New Guinea for more than 30 years, Jared Diamond presents the geographical and ecological factors that have shaped the modern world. From the viewpoint of an evolutionary biologist, he highlights the broadest movements both literal and conceptual on every continent since the Ice Age, and examines societal advances such as writing, religion, government, and technology.

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

It can come in waves - like tidal waves. It changes societies. It disrupts life. It ends lives. As far back as 3000 B.C.E. (the Bronze Age), plagues have stricken mankind. COVID-19 is just the latest example, but history shows that life continues. It shows that knowledge and social cooperation can save lives. Viruses are neither alive nor dead and are the closest thing we have to zombies. Their only known function is to replicate themselves, which can have devastating consequences on their hosts.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

In this intimate history of the extraordinary Black Plague pandemic that swept through the British Isles in 1665, Evelyn Lord focuses on the plague's effects on smaller towns, where every death was a singular blow affecting the entire community. Lord's fascinating reconstruction of life during plague times presents the personal experiences of a wide range of individuals, from historical notables to common folk. The Great Plague brings this dark era to vivid life through stories of loss and survival from those who grieved, those who fled, and those who hid to await their fate.

Upon its original publication, Plagues and Peoples was an immediate critical and popular success, offering a radically new interpretation of world history. With the identification of AIDS in the early 1980s, another chapter was added to this chronicle of events, which William McNeill explores in his introduction to this edition. McNeill’s highly acclaimed work is a brilliant and challenging account of the effects of disease on human history. His sophisticated analysis and detailed grasp of the subject make this book fascinating to listen to.

The emperor Justinian reunified Rome's fractured empire by defeating the Goths and Vandals. At his capital in Constantinople, he built the world's most beautiful building, married the most powerful empress, and wrote the empire's most enduring legal code, seemingly restoring Rome's fortunes for the next five hundred years. Then, in the summer of 542, he encountered a flea. The ensuing outbreak of bubonic plague killed 5,000 people a day in Constantinople and nearly killed Justinian himself.

Favereau takes us inside one of the most powerful sources of cross-border integration in world history. The Horde was the central node in the Eurasian commercial boom of the 13th and 14th centuries and was a conduit for exchanges across thousands of miles. Its unique political regime - a complex power-sharing arrangement among the khan and the nobility - rewarded skillful administrators and diplomats and fostered an economic order that was mobile, organized, and innovative.

Despite advances in health care, infectious microbes continue to be a formidable adversary to scientists and doctors. Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

In Medical Bondage, Cooper Owens examines a wide range of scientific literature and less formal communications in which gynecologists created and disseminated medical fictions about their patients, such as their belief that black enslaved women could withstand pain better than white "ladies". Even as they were advancing medicine, these doctors were legitimizing, for decades to come, groundless theories related to whiteness and blackness, men and women, and the inferiority of other races or nationalities.

In this fresh approach to the history of the Black Death, John Hatcher, a world-renowned scholar of the Middle Ages, recreates everyday life in a mid-14th-century rural English village. By focusing on the experiences of ordinary villagers as they lived - and died - during the Black Death (A.D. 1345-50), Hatcher vividly places the reader directly into those tumultuous years and describes in fascinating detail the day-to-day existence of people struggling with the tragic effects of the plague.

What won't we try in our quest for perfect health, beauty, and the fountain of youth? Well, just imagine a time when doctors prescribed morphine for crying infants. When liquefied gold was touted as immortality in a glass. And when strychnine - yes, that strychnine, the one used in rat poison - was dosed like Viagra. Looking back with fascination, horror, and not a little dash of dark, knowing humor, Quackery recounts the lively, at times unbelievable, history of medical misfires and malpractices.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

The most fatal virus known to science, rabies kills nearly 100 percent of its victims once the infection takes root in the brain. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh, fascinating, and often wildly entertaining look at one of mankind’s oldest and most fearsome foes.