The Song of the Cell
An Exploration of Medicine and the New Human
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Narrated by:
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Dennis Boutsikaris
About this listen
Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize!
Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more!
In The Song of the Cell, the extraordinary author of the Pulitzer Prize-winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” (Oprah Daily).
Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them “cells.”
The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.
Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human.
“In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” (The New Yorker).
PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio.
©2022 Siddhartha Mukherjee, M.D. All rights reserved. (P)2022 Simon & Schuster, Inc. All rights reserved.Listeners also enjoyed...
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An Epidemic of Absence asks what will happen in developing countries, which, as they become more affluent, have already seen an uptick in allergic disease: Will India end up more allergic than Europe? Velasquez-Manoff also details a controversial underground movement that has coalesced around the treatment of immune-mediated disorders with parasites. Against much of his better judgment, he joins these do-it-yourselfers and reports his surprising results.
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The point of view from a Veterinarian immunologist
- By rtgymnast on 11-03-17
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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Story
p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- By: Juan Enriquez, Steve Gullans
- Narrated by: Rob Shapiro
- Length: 10 hrs and 50 mins
- Unabridged
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Overall
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Performance
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Story
Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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fascinating ideas and science
- By Joel on 07-04-15
By: Juan Enriquez, and others
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- By: Nathan H. Lents
- Narrated by: L.J. Ganser
- Length: 7 hrs and 54 mins
- Unabridged
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Performance
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We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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From Pointless Bones to Broken Genes to...Aliens?
- By Katy.LED on 12-04-18
By: Nathan H. Lents
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- By: Rob DeSalle, Susan L. Perkins
- Narrated by: Stephen McLaughlin
- Length: 7 hrs and 25 mins
- Unabridged
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Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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The Language of Life
- DNA and the Revolution in Personalized Medicine
- By: Francis S. Collins
- Narrated by: Greg Itzin
- Length: 10 hrs and 45 mins
- Unabridged
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A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.
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The future of medicine
- By Ronald E on 04-12-10
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Life Unfolding
- How the Human Body Creates Itself
- By: Jamie A. Davies
- Narrated by: Napoleon Ryan
- Length: 9 hrs and 56 mins
- Unabridged
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Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?
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Fascinating Biology ; Distracting Narration
- By Tim on 03-01-15
By: Jamie A. Davies
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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A Short History of Medicine
- Modern Library Chronicles
- By: Frank Gonzalez-Crussi
- Narrated by: John McDonough
- Length: 9 hrs and 26 mins
- Unabridged
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Praised for his erudite writing, renowned scientist Frank Gonzalez-Crussi penned this concise history of medicine, beginning with the most primitive health-care practices and ending with the technology of modern medicine that we enjoy today. As with all Modern Library Chronicles, A Short History of Medicine is a wonderful primer for anyone interested in the subject.
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Dull and Disorganized
- By Amazon Customer on 05-21-08
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- By: Kevin Davies
- Narrated by: Kevin Davies
- Length: 16 hrs and 17 mins
- Unabridged
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Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- By Samuel Finlayson on 01-25-21
By: Kevin Davies
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The Invention of Surgery
- A History of Modern Medicine: From the Renaissance to the Implant Revolution
- By: David Schneider MD
- Narrated by: Peter Noble
- Length: 23 hrs and 4 mins
- Unabridged
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Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.
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Yup, this is the one you’re looking for...
- By richard clark on 07-19-20
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Chronic
- The Hidden Cause of the Autoimmune Pandemic and How to Get Healthy Again
- By: Steven Phillips MD, Dana Parish, Kristin Loberg
- Narrated by: Teri Schnaubelt, Thomas Allen
- Length: 10 hrs and 42 mins
- Unabridged
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In this timely book, Steven Phillips, MD, and his former patient, Sony singer-songwriter Dana Parish, reveal striking evidence that a broad range of common infections, from COVID-19 to Lyme and many others, cause a variety of autoimmune, psychiatric, and chronic conditions. Chronic explores the science behind what makes them difficult to diagnose and treat, debunks widely held beliefs by doctors and patients alike, and provides solutions that empower sufferers to reclaim their lives.
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A must read book
- By Amazon Customer on 03-01-21
By: Steven Phillips MD, and others
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In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field is horizontal gene transfer (HGT), or the movement of genes across species lines. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT. In The Tangled Tree David Quammen chronicles these discoveries through the lives of the researchers who made them.
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Too many equations, not enough insights
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Beginning in the 1970s, several scientific breakthroughs promised to transform the creation of new medicines. As investors sought to capitalize on these Nobel Prize-winning discoveries, the biotech industry grew to thousands of small companies around the world. Each sought to emulate what the major pharmaceutical companies had been doing for a century or more, but without the advantages of scale, scope, experience, and massive resources. From Breakthrough to Blockbuster focuses on both the companies themselves and the broader biotech ecosystem that supports them.
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Wonderful book!
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What listeners say about The Song of the Cell
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- Anonymous User
- 01-07-23
Song of the cell is detailed and fascinating
Helpful, detailed cell biology and physiology from a researcher and physician who provides in-depth and accurate biology in terms that can be understood by non-biologists!
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- Marilyn bird
- 02-02-23
song of the cell
I loved this and didn't think I would. what an amazing at US, the human being.
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- H. Singh
- 12-19-22
awesome book
need to be read by all students interested in cutting edge science. easy to understand.
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- Anonymous User
- 03-05-23
Good but…
This author is my inspiration and source of knowledge about cancer and cell biology for many years. I read all of his books and I love them. This book is a little bit chaotic and unstructured comparing to “Emperor… “. At the beginning he is referring to his own clinical tests which is very narrow perspective. I couldn’t go through organs chapter. Clearly this is not strongest part of the author. Also there are too many non-scientific thoughts that don’t fit to this book. I think that the author was on high pressure to publish yet clearly he had no vision for his next book. On the other hand “emperor … “ is one of the best books I’ve ever read. So this is unfair battle ;)
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- Kevin C. Yam
- 05-01-23
Beautiful Writing on a Complex Topic
Amazing survey on the history of cell biology and an overview of all the amazing medical innovations on the horizon. Highly recommend. Great book for anyone looking for a “Life Science Primer”.
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- Anonymous User
- 06-04-23
the cell is singing
An excellent, historical yet prescient scientific exercise bringing together the past and present. Underscores the scientific rigor and lifelong dedication that eventually open a secret of nature. His final chapter should be read by any curious mind considering a career in biological research.
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- Paul Zolty
- 01-24-23
Phenomenal
Phenomenal book. Phenomenally narrated. Must read by physicians and lay people alike. If you’re early in your medical career, this one may perhaps even serve to redirect the trajectory of your chosen specialty.
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- Amazon Customer
- 08-18-23
Fascinating
Narration also excellent. Medical and science nerds will love this playing in the car on the way to work
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- Frank Gaertner
- 09-22-23
Wonderful! I love this book!
We are conscious beings made of cells self-assembled by atom’s that are manifested by quarks from Paul Dirac’s seething seas (fields) of annihilating virtual particles and antiparticles that brawl about to produce the illusion of matter from probabilistic waves that form in empty space. Atomistic illusions produce wholistic illusions to manifest conscious beings who ultimately start the whole illusion all over again. In the meantime we are still trying to figure out cancer and are totally impressed by the cleverness of the cells that cause the disease. As one can tell I really got excited by the last chapter and pages in this audible book and have added the Song of the Cell to the end of my new book OSAU-3, Who is Us, Thank you!!
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- Mama&cubs
- 03-12-24
Another masterpiece
Over time, I’ve come to expect superb vocabulary, an engaging writing style, and complicated information presented for the layman from this author, and this book is no exception. Loved it.
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