On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

Hope is much more than wishful thinking. Science tells us that it is the most predictive indicator of well-being in a person's life. Hope is measurable. It is malleable. And it changes lives. In Hope Rising, Casey Gwinn and Chan Hellman reveal the latest science of hope using nearly 2,000 published studies, including their own research. Based on their findings, they make an impassioned call for hope to be the focus not only of our personal lives, but of public policy for education, business, social services, and every part of society.

In Being Mortal, best-selling author Atul Gawande tackles the hardest challenge of his profession: how medicine can not only improve life but also the process of its ending. Medicine has triumphed in modern times, transforming birth, injury, and infectious disease from harrowing to manageable. But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit.

In this special compilation, you'll hear exhilarating excerpts from classic interviews with 14 stars of comedy, including Tracey Ullman on her zany characters, Chris Rock on growing up small and black in a white neighborhood, Carol Leifer on the inspiration for her brand of cabaret comedy, and Henny Youngman on his famous line, "Take my wife, please."

Every medical decision - whether to have chemotherapy, an X-ray, or surgery - is a risk, no matter which way you choose. In You Bet Your Life, physician Paul A. Offit argues that, from the first blood transfusions 400 years ago to the hunt for a COVID-19 vaccine, risk has been essential to the discovery of new treatments. More importantly, understanding the risks is crucial to whether, as a society or as individuals, we accept them.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

Your doctor suggests you take a drug to lower your blood pressure, but you’ve read that it has risky side effects for some patients. Do you take the drug given the risks it entails, or do you risk living with high blood pressure? The answers to questions like this can be maddeningly—even dangerously—elusive. Drs. Groopman and Hartzband provide groundbreaking guidance any patient can use to tailor their medical choices to their own physical and emotional needs.

You get ready to die the way you get ready for a trip. Start by realizing you don't know the way. Listen to a few travel guides. Study the language, look at maps, gather equipment. Let yourself imagine what it will be like. Pack your bags. This book is one of those travel guides - a guide to preparing for your own death and the deaths of people close to you. The fact of death is hard to believe. Sallie Tisdale explores our fears and all the ways death and talking about death make us uncomfortable - but she also explores its intimacies and joys.

Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than 60 years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

The struggle to perform well is universal: each one of us faces fatigue, limited resources, and imperfect abilities in whatever we do. But nowhere is this drive to do better more important than in medicine, where lives are on the line with every decision. In this book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable.

Sometimes in medicine the only way to know what is truly going on in a patient is to operate, to look inside with one's own eyes. This audio is exploratory surgery on medicine itself, laying bare a science not in its idealized form, but as it actually is - complicated, perplexing, and profoundly human. Atul Gawande offers an unflinching view from the scalpel's edge, where science is ambiguous, information is limited, the stakes are high. In dramatic and revealing stories of patients and doctors, he explores how deadly mistakes occur and why good surgeons go bad.

By turns heartbreaking, hilarious, and utterly human, The House of God is a mesmerizing and provocative journey that takes us into the lives of Roy Basch and five of his fellow interns at the most renowned teaching hospital in the country.

In a community struggling to overcome systemic poverty and violence, The Whole Language shows how those at Homeboy Industries fight despair and remain generous, hopeful, and tender. When Saul was thirteen years old, he killed his abusive stepfather in self-defense; after spending twenty-three years in juvenile and adult jail, he enters the Homeboy Industries training and healing programs and embraces their mission.

In Cured, Dr. Rediger digs down to the root causes of illness, showing how to create an environment that sets the stage for healing. He reveals the patterns behind healing and lays out the physical and mental principles associated with recovery: first, we need to physically heal our diet and our immune systems. Next, we need to mentally heal our stress response and our identities. Through rigorous research, Dr. Rediger shows that much of our physical reality is created in our minds. Our perception changes our experience, even to the point of changing our physical bodies.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

In Shock is a riveting first-hand account from a young critical care physician, who in the passage of a moment is transfigured into a dying patient. This transposition, coincidentally timed at the end of her medical training, instantly lays bare the vast chasm between the conventional practice of medicine and the stark reality of the prostrate patient.

At one time heart disease was a death sentence. By the middle of the 20th century, it was killing millions, and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time.

An epic story told by a unique voice in Ameri­can medicine, One Doctor describes life-changing experiences in the career of a distinguished physi­cian. In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

For centuries, the human heart seemed beyond our understanding: an inscrutable shuddering mass that was somehow the driver of emotion and the seat of the soul. As cardiologist and best-selling author Sandeep Jauhar tells in The Heart, it was only recently that we demolished age-old taboos and devised the transformative procedures that changed the way we live. Deftly alternating between historical episodes and his own work, Jauhar tells the colorful and little known story of the doctors who risked their careers and the patients who risked their lives to know and heal our most vital organ.

Each of us will know physical pain in our lives, but none of us knows when it will come or how long it will stay. Today as much as 10 percent of the population of the United States suffers from chronic pain. It is more widespread, misdiagnosed, and undertreated than any major disease. While recent research has shown that pain produces pathological changes to the brain and spinal cord, many doctors and patients still labor under misguided cultural notions and outdated scientific dogmas.

Falling into the Fire is psychiatrist Christine Montross's thoughtful investigation of the gripping patient encounters that have challenged and deepened her practice. Beautifully written, deeply felt, Falling into the Fire brings us inside the doctor’s mind, illuminating the grave human costs of mental illness as well as the challenges of diagnosis and treatment. At once rigorous and meditative, Falling into the Fire is an intimate portrait of psychiatry, allowing the reader to witness the humanity of the practice and the enduring mysteries of the mind.

A classic of patient empowerment, Peace, Love & Healing offered the revolutionary message that we have an innate ability to heal ourselves. Now proven by numerous scientific studies, the connection between our minds and our bodies has been increasingly accepted as fact throughout the mainstream medical community. In a new introduction, Dr. Bernie Siegel highlights current research on the relationships among consciousness, psychosocial factors, attitude, and immune function.

When Damon Tweedy begins medical school, he envisions a bright future where his segregated, working-class background will become largely irrelevant. Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career.

Hoping for the stability he needs to start a family, Sandeep Jauhar, an attending cardiologist, accepts a position at a massive teaching hospital on the outskirts of Queens. With a decade's worth of elite medical training behind him, he is eager to settle down and reap the rewards of countless sleepless nights. Instead, he is confronted with sobering truths. Doctors' morale is low and getting lower.

In her former career as an English professor, Theresa Brown had been shielded from the harsh reality of death. That all changed the day she decided to become an oncology nurse. In Critical Care, Theresa writes powerfully and honestly about her first year on the hospital floor. With great compassion and a disarming sense of humor, she shares the trials and triumphs of her patients and comes to realize that caring for a patient means much more than simply treating a disease.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Imagine finding a glimmer of good news in a diagnosis of Alzheimer's. And imagine how that would change the outlook of the five million Americans who suffer from Alzheimer's disease and other dementias, not to mention their families, loved ones, and caretakers. A neurologist who's been specializing in dementia and memory loss for more than 20 years, Dr. Gayatri Devi rewrites the story of Alzheimer's by defining it as a spectrum disorder - like autism, Alzheimer's is a disease that affects different people differently.