From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

In this revolutionary book, renowned physician Gabor Maté eloquently dissects how in Western countries that pride themselves on their healthcare systems, chronic illness and general ill health are on the rise. Nearly 70 percent of Americans are on at least one prescription drug; more than half take two. In Canada, every fifth person has high blood pressure. In Europe, hypertension is diagnosed in more than 30 percent of the population. And everywhere, adolescent mental illness is on the rise. So what is really “normal” when it comes to health?

Brimming with fascinating historical details and modern medical wonders, this important audiobook is a fascinating glimpse into the struggles and "eureka!" moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee's signature eloquence and passionate prose, The Laws of Medicine is a critical book not just for those in the medical profession but for everyone who is moved to better understand how their health and well-being are being treated.

Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

At the age of thirty-six, on the verge of completing a decade’s worth of training as a neurosurgeon, Paul Kalanithi was diagnosed with stage IV lung cancer. One day he was a doctor treating the dying, and the next he was a patient struggling to live. And just like that, the future he and his wife had imagined evaporated.

When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

Most books about the history of humanity pursue either a historical or a biological approach, but Dr. Yuval Noah Harari breaks the mold with this highly original book. From examining the role evolving humans have played in the global ecosystem to charting the rise of empires, Sapiens integrates history and science to reconsider accepted narratives, connect past developments with contemporary concerns, and examine specific events within the context of larger ideas.

Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body - how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted."

With compassion and candor, leading neurosurgeon Henry Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life. If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached surgeons, this gripping, brutally honest account will make you think again.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

Bill Bryson has been an enormously popular author both for his travel books and for his books on the English language. Now, this beloved comic genius turns his attention to science. Although he doesn't know anything about the subject (at first), he is eager to learn, and takes information that he gets from the world's leading experts and explains it to us in a way that makes it exciting and relevant.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on the Higgs boson and extra dimensions but now also on our deepest personal questions. Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void?

Most history is hierarchical: it's about emperors, presidents, prime ministers, and field marshals. It's about states, armies, and corporations. It's about orders from on high. Even history "from below" is often about trade unions and workers' parties. But what if that's simply because hierarchical institutions create the archives that historians rely on? What if we are missing the informal, less well documented social networks that are the true sources of power and drivers of change?

In 40 years, Earth's population will reach 10 billion. Can our world support that? What kind of world will it be? Those answering these questions generally fall into two deeply divided groups - Wizards and Prophets, as Charles Mann calls them in this balanced, authoritative, nonpolemical new book. The Prophets, he explains, follow William Vogt, a founding environmentalist who believed that in using more than our planet has to give, our prosperity will lead us to ruin.

An extraordinary mythology has grown up around the Third Reich that hovers over political and moral debate even today. Adam Tooze's controversial book challenges the conventional economic interpretations of that period.

Elinor Cleghorn became an unwell woman 10 years ago. She was diagnosed with an autoimmune disease after a long period of being told her symptoms were anything from psychosomatic to a possible pregnancy. As Elinor learned to live with her unpredictable disease, she turned to history for answers, and found an enraging legacy of suffering, mystification, and misdiagnosis. In Unwell Women, Elinor Cleghorn traces the almost unbelievable history of how medicine has failed women by treating their bodies as alien and other, often to perilous effect.

Harry Cliff - a University of Cambridge particle physicist and researcher on the Large Hadron Collider - sets out in pursuit of answers. He ventures to the largest underground research facility in the world, deep beneath Italy's Gran Sasso mountains, where scientists gaze into the heart of the Sun using the most elusive of particles, the ghostly neutrino. He visits CERN in Switzerland to explore the "Antimatter Factory," where the stuff of science fiction is manufactured daily (and we're close to knowing whether it falls up).

For decades Richard Dawkins has been the world's most brilliant scientific communicator, consistently illuminating the wonders of nature and attacking faulty logic. Science in the Soul brings together 42 essays, polemics, and paeans - culled from personal papers, newspapers, lectures, and online salons - all written with Dawkins' characteristic erudition, remorseless wit, and unjaded awe of the natural world.

For a quarter-century, from the end of Watergate to the aftermath of the Cold War, no Republican won the presidency without his help or ran the White House without his advice. James Addison Baker III was the indispensable man for four presidents because he understood better than anyone how to make Washington work at a time when America was shaping events around the world. The Man Who Ran Washington is a pause-resisting portrait of a power broker who influenced America's destiny for generations.

The number-one best-selling author of The Future of the Mind traverses the frontiers of astrophysics, artificial intelligence, and technology to offer a stunning vision of man's future in space, from settling Mars to traveling to distant galaxies. Formerly the domain of fiction, moving human civilization to the stars is increasingly becoming a scientific possibility - and a necessity. Whether in the near future due to climate change and the depletion of finite resources or in the distant future due to catastrophic cosmological events, humans will one day need to leave Earth.

More than 40 years after it ended, the Vietnam War continues to haunt our country. We still argue over why we were there, whether we could have won, and who was right and wrong in their response to the conflict. When the war divided the country, it created deep political fault lines that continue to divide us today. Now, continuing in the tradition of their critically acclaimed collaborations, the authors draw on dozens and dozens of interviews in America and Vietnam to give us the perspectives of people involved at all levels of the war.

Over the few short decades that followed Christopher Columbus' first landing in the Caribbean in 1492, Spain conquered the two most powerful civilizations of the Americas: the Aztecs of Mexico and the Incas of Peru. Hernán Cortés, Francisco Pizarro, and the other explorers and soldiers who took part in these expeditions dedicated their lives to seeking political and religious glory, helping to build an empire unlike any the world had ever seen. But centuries later, these conquistadors have become the stuff of nightmares.

Scientists are confident that life exists elsewhere in the universe. Yet rather than taking a realistic approach to what aliens might be like, we imagine that life on other planets is the stuff of science fiction. The time has come to abandon our fantasies of space invaders and movie monsters and place our expectations on solid scientific footing. But short of alien's landing in New York City, how do we know what they are like?

Here for the first time, in rich human, political, and scientific detail, is the complete story of how the bomb was developed, from the turn-of-the-century discovery of the vast energy locked inside the atom to the dropping of the first bombs on Japan. Few great discoveries have evolved so swiftly - or have been so misunderstood. From the theoretical discussions of nuclear energy to the bright glare of Trinity, there was a span of hardly more than 25 years.

The author of The Power of Habit and “master of the life hack” (GQ) explores the fascinating science of productivity and offers real-world takeaways to apply your life, whether you’re chasing peak productivity or simply trying to get back on track.