Prairie Nightingale is both the midlife mother of two teenage girls and a canny entrepreneur who has turned homemaking into a salaried profession. She’s also fascinated with the gritty details of other people’s lives. So when seemingly perfect Lisa Radcliffe, a member of her former mom-friends circle, suddenly disappears, it’s in Prairie’s nature to find out why. Given her innate talent for vital pattern recognition, Prairie is out to catch a few clues by taking a long, hard look at everyone in Lisa’s life—and uncovering their secrets.

New York City, 1929. Young Theo Sterling’s world begins to unravel as the Great Depression exerts its icy grip. He finds it hard to relate to his parents: His father, a Jewish self-made businessman, refuses to give up on the American dream, and his mother, a refugee from religious persecution in Mexico, holds fast to her Catholic faith. When disaster strikes the family, Theo must learn who he is.

Charlie Tannehill and her twin sister, Maggie, are just eight years old when an unfortunate scientific discovery upends their world—and the world order. The revelation? Extinction, encoded in every creature’s DNA. The expiration date for humans? Only four generations away. A decade later, unsure of what tomorrow holds, Charlie and Maggie enroll as counselors in a government-run human-husbandry program.

Blood and power bind three generations of women in the Ozark Mountains. So does an evil that’s followed them across the decades. 1931. Gracelynn Doherty lives peacefully on Tin Mountain, helping her adoptive granny work her cures. Despite whispers that the women are witches, the superstitious locals still seek them out, whether to remedy arthritis or a broken heart. But when evangelist Josiah Bellflower comes to town promising miracle healing, full bellies, and prosperity, his revivals soon hold Tin Mountain in thrall—and Granny in abject fear. Granny recognizes Josiah.

After ten years away to build a family, Mallory returns to Floreana Island in the Galápagos, and to Gavin, the mentor with whom she had a long-ago affair. Their project is to build nests to revive the vulnerable penguin population. But Mallory doesn’t dare tell Gavin why she’s really come back. Then she discovers old journals hidden in a lava cave—confessions of another woman who needed to disappear.

Grim Wolds, England: Winifred Notty arrives at Ensor House prepared to play the perfect governess—she’ll dutifully tutor her charges, Drusilla and Andrew, tell them bedtime stories, and only joke about eating children. But long, listless days spent within the estate’s dreary confines come with an intimate knowledge of the perversions and pathetic preoccupations of the Pounds family—Mr. Pounds can’t keep his eyes off Winifred’s chest, and Mrs. Pounds takes a sickly pleasure in punishing Winifred for her husband’s wandering gaze.

Devon Ferrell and Richard Belmont are engaged, in love, and from two different worlds. Devon is as eager to please Richard’s elite parents as she is to leave the traumas of her childhood behind. After all, the Belmonts are her family now. But being brought into the fold is unbalancing her. There are the piercing stares from Richard’s brother, the confounding whispers about Devon’s moods and health. It’s as if the Belmonts are looking for reasons to reject her, to fill her with self-doubt and put her on edge. It’s working. And no one seems to be on Devon’s side. Not even Richard.

In 1960, Senator John F. Kennedy makes a historic run for the White House. Despite concerns about his Catholicism, Kennedy’s outward charm is winning the country over, but his inner demons are putting his candidacy in danger and risk destroying his political career. That same year, Caitlin Russo, a former cop turned reporter, is devoting her skills to finding her husband’s killer. His job as a CIA operative posed its fair share of risks, but when Caitlin discovers his notes about the case that led to his death, she knows there’s more to the story than simple tragedy.

Hollywood, 1955. As head costume designer for Lux Pictures, Lena Taylor hears startling confessions from the biggest movie stars. She knows how to keep their secrets—after all, none of their scandals can match her own. Lena was once Elsie Gruner, the daughter of an Ohio dressmaker. Her gift for fashion design helped her win a coveted spot at an art academy in Rome. While in Italy, she became enthralled by the charismatic Julia, who drew her into a shadowy world of jazz clubs, code words, and mysterious deliveries.

On prom night, Caroline Winterfield walked away from the ruins of an abandoned mansion called Haven Cliff and into the woods…never to be seen again. Only her three best friends know what really happened. But a secret is a secret, and a promise is a promise—even when it shatters lifelong friendships. On the twenty-fifth anniversary of that night, Midge, Kelly, and Talia reunite at Haven Cliff, now a gleaming architectural jewel. But they aren’t alone. Someone is watching.

Stacey is the dusty air, the cracked soil, the drought. To thirteen-year-old Bethany Sloane, she’s everything. Abandoned by her mother at a remote African boarding school, Bethany will do anything to stay in Stacey’s good graces. And that means learning the rules of each twisted game.

Eddie Asher arrives at Hudson Valley Psychiatric Hospital panicked that he may have murdered his brother’s fiancée, Lucy, with whom he shared a profound kinship. He can’t imagine doing such a terrible thing, but Eddie hasn’t been himself lately. Eddie’s anxiety is nothing new to Pär, the one Eddie calls his Other, who protects Eddie from truths he’s too sensitive to face. Or so Pär says. Troubled by Pär’s increasing sway over his life, Eddie seeks out Dr. Richard Montgomery, a specialist in dissociative identities.

Jeckle Island offers Rachel’s children the chance to spend summers roaming wild and free, as long as they follow the rules. But when her son comes face to face with a terror they dare not speak of, she must prepare for their perfect world to change. Forever.

Sometimes, it’s best to mind your own business. Felix Eastwood is your average guy, except for the fact that he can see the spirits of the dead. Lilith Lavelle is a fraudulent psychic, plying her trade on social media. When Felix stumbles across an advertisement for Lilith Lavelle’s Psychic Cleansing Services, he hires her under the pretense that his family is being haunted, hoping to expose her as a scam artist. By trying to play the hero, Felix puts his family in grave danger.

Lilly Bly desperately wants to have a baby. She is struggling with infertility and bad spending habits when her husband, Jack, gets a new job that moves them from Chicago to a small town in Wisconsin. Impractical Lilly falls in love with a decrepit mansion well out of their price range—she is convinced that she will finally get pregnant and have a baby in this house—and Jack agrees to it. But when Lilly learns that her dream house was the site of a gruesome triple homicide/suicide in the 1950s, she begins to experience strange occurrences that soon lead her to believe the house is haunted.

Remi Russell knows this playbook all too well. She’s seen it unfold five times over her six years at The Sophisticate, a once prominent but now struggling women’s magazine. So when the publication needs rescuing yet again, an intriguing new chief digital officer, Jason Ashbloome, arrives with a revolutionary plan beyond the usual workforce cuts. He proposes integrating MAUDE, an innovative AI software, to make the magazine more efficient. Remi fears she could lose her job to a machine, and worse, the magazine she loves might lose its humanity altogether.

When seventeen-year-old Isla Richardson is killed in a hit-and-run incident, a community’s lives are thrown into disarray. For Isla’s mum, Abby, it is her second devastating bereavement, having lost her husband five years ago. As Abby begins to uncover secrets about Isla’s life, she’s forced to rethink everything she thought she knew about her family.

When Bunny Linden abandons her three children with her older sister, Jayne, in 1972, she knows Jayne will be the perfect mother. The mother Bunny, a teen runaway, could never be. As months turn into years without word, Jayne and her husband, Rodger, a rising journalism star, strive to give the children the opportunity to flourish and feel loved. When Jayne and Rodger finally have a child of their own, a seemingly stable home is built. But then, after nearly a decade, Bunny resurfaces and sets a chain of events in motion that detonates all their lives.

Amid the heralded springtime traditions and fabulous splendor of the Kentucky Derby, two Boston couples—longtime friends—indulge in a once-in-a-lifetime getaway. The weekend feels like a winner. It’s a milestone-birthday present for the newly—and reluctantly—turned forty Drew Starling. Her husband, Nate, has spared no expense, despite the mounting gambling debts that Drew knows nothing about. He’s certain that with his lucky charm, Drew, by his side, he can reverse his misfortunes at Churchill Downs.

Blood and power bind three generations of women in the Ozark Mountains. So does an evil that’s followed them across the decades. 1931. Gracelynn Doherty lives peacefully on Tin Mountain, helping her adoptive granny work her cures. Despite whispers that the women are witches, the superstitious locals still seek them out, whether to remedy arthritis or a broken heart. But when evangelist Josiah Bellflower comes to town promising miracle healing, full bellies, and prosperity, his revivals soon hold Tin Mountain in thrall—and Granny in abject fear. Granny recognizes Josiah.

Best friends Miranda Montana, Germaine St. Germaine-Chang, and Sicily Bell were the darlings of Hollywood who rose from teen success to in-demand idols of screaming fans and paparazzi. They rode the momentum like there was no tomorrow. But nothing lasts forever. Now Miranda, the wild-child movie star, drifts from rehab to dead-end relationships as she tries for a comeback from a very public fall from grace. Germaine, the daughter of billionaire hotel moguls, has lost her purpose.

The president of the United States has terminal cancer. Chief of Staff Eli James, his faithful consigliere and best friend, is one of the few who know. But just as the president’s condition mysteriously improves, Eli’s hit with another blow: his daughter has cancer too. Hell-bent on helping her, Eli turns to Big Pharma’s top lobbyist for advice, but their encounter yields more questions than answers. As he races along a twisted trail to the truth, he stumbles upon a devastating cover-up worth billions of dollars—and millions of lives.

Missouri, 1955. Loretta Davenport has led an isolated life as a young mother and a wife to Pete, an ambitious assistant professor at a Bible college. They’re the picture of domestic tranquility—until a local girl is murdered and Loretta begins receiving messages from beyond. Pete dismisses them as delusions of a fevered female imagination. Loretta knows they’re real—and frightening.

Lestari Aris is a woman on the edge. Her tattoo studio on Karangahape Road is hammered by burglaries; the hangers-on in her life, from a teenage runaway to a married cop, are bonded to her for reasons she can’t fathom. And years after Lestari’s father disappeared, her Indonesian mother is still lost in a self-medicated blur. When a murder in Symonds Street Cemetery whirls Lestari into the orbit of an unpredictable drug, she uncovers a decades-long covert clinical study targeting rough sleepers and others on the fringes – and its dark connections with her own life and history.

At high noon on a hot summer’s day, a beautiful young woman shoots the mayor dead. So begins a story of passion and betrayal in a quiet Tuscan village, leading to a sensational trial. The defence team, headed by the brilliant but unhappy Carlo Rienzi, uncovers a sinister conspiracy of silence that threatens to split the community. Can Carlo persuade the judge to grant clemency in what appears to be an open-and-shut case? Can the law intervene in the brutal tradition of vendetta?

Reuben thought he’d spend the rest of his life with Beth, until she broke his heart six months ago. He’s not even remotely over her, so he’s devastated to hear she’s getting married—this weekend. Now he’s faced with the ultimate question: what should he do on the day of the wedding? Grieve? Disrupt the ceremony? Or do everything in his power to pretend it’s not happening? Enlisting the help of his friends, Reuben is all set to mark the occasion with distraction on a grand scale: Ferraris, champagne, and a VIP box at the races.

Twenty years ago, during a family holiday on the savage and remote island of Little Auger, eleven-year-old Hazel left her bed and was never seen again. The unanswered questions surrounding Hazel’s disappearance tore three families apart and the girls left behind all experience their own terrible guilt. Roz, because she broke a promise; Catrin, because it was her idea; and Nina, who slept through it all. Their friendship never recovers and all three women go on to lead vastly different lives.

Los Alamos, 1943. The US Army has gathered scientists to create the world’s first nuclear weapon. Their families, abruptly moved to the secret desert base with no explanation, have simple orders: Stand by. Make do. Above all, don’t ask questions. Christine, forced to abandon her art restoration business in New York for her husband’s career, struggles to reinvent herself and cope with his increasing aloofness. Gertie, the inquisitive teenage daughter of a German Jewish refugee physicist enlists Christine to help her unravel hidden truths and deal with parents haunted by their past.

Cassie Harper anticipates a week of prenuptial celebrations when she agrees to spend the week before her best friend Emily’s wedding at the remote and foreboding Hideaway House. Nestled deep in the heart of a secluded forest, the estate is the perfect backdrop for a series of lavish parties. But as Cassie arrives, she feels nothing but a growing sense of dread. As the days tick by in the eerie isolation of the estate, it becomes clear that there’s more to this place than meets the eye. Surrounded by sprawling woods, she finds herself entangled in the estate’s unsettling past.

Introducing Jack West a tenacious Houston Homicide Detective, a man who believes even the dregs of society deserve justice. After solving an exhausting murder case involving teenagers, Jack and his partner, Dawson Luck are assigned a cold case dating back 25 years. One case: an unsolved murder of a woman, found dead behind a seedy motel; the other about a missing prostitute. Digging into the cases, a fresh murder case is called in. A wealthy couple is found dead in an affluent residential area. It appears to be a murder- suicide and this new case takes precedence.