In July 1952, Dr. Walter Freeman arrived at the gates of a West Virginia asylum. In his medical bag he carried two metal picks and a surgical hammer. He had invented a “cheap, easy” ten-minute lobotomy. The press described it as a miracle cure, a new frontier in psychosurgery. That summer, in just twelve days, Freeman lobotomized 228 men, women, and children in West Virginia’s public mental hospitals. His blitzkrieg of brain surgery became known as “Operation Ice Pick,” named after the tools he wielded.

The prize-winning and best-selling author of Say Nothing presents a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

Medical Apartheid is the first and only comprehensive history of medical experimentation on African Americans. Starting with the earliest encounters between black Americans and Western medical researchers and the racist pseudoscience that resulted, it details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge - a tradition that continues today within some black populations.

We know it simply as "the pill", yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic.

In this partially autobiographical work, best-selling author Lewis Thomas offers insights on subjects as wide-ranging as gender differences, how it feels to be a patient, human vs. computer intelligence, the future of cancer research, and the longevity of the planet—interspersing all with charming anecdotes about his family, his colleagues and himself.

As a health-care journalist, Kate Pickert knew the emotional highs and lows of medical treatment well - but always from a distance, through the stories of her subjects. That is, until she was unexpectedly diagnosed with an aggressive type of breast cancer at the age of 35. As she underwent more than a year of treatment, Pickert realized that the popular understanding of breast care in America bears little resemblance to the experiences of today's patients and the rapidly changing science designed to save their lives.

An updated third edition of the renowned feminist’s most diverse and timeless collection of essays, with a new foreword written by Emma Watson and new material written and read by Gloria Steinem.

Blood carries life, yet the sight of it makes people faint. It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquitousness, the few tablespoons of blood discharged by 800 million women are still regarded as taboo: menstruation is perhaps the single most demonized biological event.

For centuries, doctors have struggled to define mental illness - how do you diagnose it, how do you treat it, how do you even know what it is? In search of an answer, in the 1970s a Stanford psychologist named David Rosenhan and seven other people - sane, normal, well-adjusted members of society - went undercover into asylums around America to test the legitimacy of psychiatry's labels. Rosenhan's watershed study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever.

First published in 1991, Backlash made headlines and became a best-selling classic for its thoroughgoing debunking of a decade-long antifeminist backlash against women’s advances. As Faludi writes in a new preface for this edition, much has changed in the intervening years. This startling and essential book helps explain why women’s freedoms are still so demonized and threatened - and urges us to choose a different future.

By the time Rock Hudson's death in 1985 alerted all America to the danger of the AIDS epidemic, the disease had spread across the nation, killing thousands of people and emerging as the greatest health crisis of the 20th century. America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously?

On the eve of International Women's Day in 2015, the Chinese government arrested five feminist activists and jailed them for 37 days. The Feminist Five became a global cause célèbre, with Hillary Clinton speaking out on their behalf and activists inundating social media with #FreetheFive messages. But the Five are only symbols of a much larger feminist movement of civil rights lawyers, labor activists, performance artists, and online warriors prompting an unprecedented awakening among China's educated, urban women.

When Queen Victoria stepped onto the throne of Great Britain and Ireland in 1837, gone were the days when the monarch had supreme authority over the kingdom. Victoria ruled at the head of a government with which she was meant to converse, debate, and ultimately guide, and it was a job she sometimes struggled to perform. Victoria described herself as an emotional creature and blamed her gender for what she believed were her shortcomings as a monarch.

In 2012, an Oregon mother named Julie Keith opened up a package of Halloween decorations. The cheap foam headstones had been five dollars at Kmart, too good a deal to pass up. But when she opened the box, something shocking fell out: an SOS letter, handwritten in broken English.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

We know it simply as "the pill", yet its genesis was anything but simple. Jonathan Eig's masterful narrative revolves around four principal characters: the fiery feminist Margaret Sanger, who was a champion of birth control in her campaign for the rights of women but neglected her own children in pursuit of free love; the beautiful Katharine McCormick, who owed her fortune to her wealthy husband, the son of the founder of International Harvester and a schizophrenic.

Lianyungang, a booming port city, has China's most extreme gender ratio for children under four: 163 boys for every 100 girls. These numbers don't seem terribly grim, but in 10 years, the skewed sex ratio will pose a colossal challenge. By the time those children reach adulthood, their generation will have 24 million more men than women. The prognosis for China's neighbors is no less bleak: Asia now has 163 million females "missing" from its population. And gender imbalance reaches far beyond Asia....

The Latin term for the female genitalia, pudendum, means “parts for which you should be ashamed”. Until 1651, ovaries were called female testicles. The fallopian tubes are named for a man. Named, claimed, and shamed: Welcome to the story of the female body, as penned by men. Today, a new generation of (mostly) women scientists is finally redrawing the map. With modern tools and fresh perspectives, they’re looking at the organs traditionally bound up in reproduction—the uterus, ovaries, vagina—and seeing within them a new biology of change and resilience.

Following the death of her father, journalist and hospice volunteer Ann Neumann sets out to examine what it means to die well in the United States. When Ann Neumann's father was diagnosed with non-Hodgkin's lymphoma, she left her job and moved back to her hometown of Lancaster, Pennsylvania. She became his full-time caregiver - cooking, cleaning, and administering medications. When her father died, she was undone by the experience, by grief and the visceral quality of dying.

Teeth takes listeners on a disturbing journey into America's silent epidemic of oral disease, exposing the hidden connections between tooth decay and stunted job prospects, low educational achievement, social mobility, and the troubling state of our public health.

In 1968, Bruce Tucker, a Black man, went into Virginia’s top research hospital with a head injury, only to have his heart taken out of his body and put into the chest of a White businessman. Now, in The Organ Thieves, Pulitzer Prize-nominated journalist Chip Jones exposes the horrifying inequality surrounding Tucker’s death and how he was used as a human guinea pig without his family’s permission or knowledge.

When Communist Party leaders adopted the one-child policy in 1980, they hoped curbing birthrates would help lift China's poorest and increase the country's global stature. But at what cost? Now, as China closes the book on the policy after more than three decades, it faces a population grown too old and too male, with a vastly diminished supply of young workers. Mei Fong has spent years documenting the policy's repercussions on every sector of Chinese society.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

In 1875, tuberculosis was the deadliest disease in the world, accountable for a third of all deaths. A diagnosis of TB - often called consumption - was a death sentence. Then, in a triumph of medical science, a German doctor named Robert Koch deployed an unprecedented scientific rigor to discover the bacteria that caused TB. Koch soon embarked on a remedy - a remedy that would be his undoing. When Koch announced his cure for consumption, Arthur Conan Doyle, then a small-town doctor in England and sometime writer, went to Berlin to cover the event.

More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments.

Here, for the first time, is a collection of short speeches by the charismatic doctor and social activist Paul Farmer. One of the most passionate and influential voices for global health equity and social justice, Farmer encourages young people to tackle the greatest challenges of our times. Engaging, often humorous, and always inspiring, these speeches bring to light the brilliance and force of Farmer's vision in a single, accessible volume.

This comprehensive and gripping narrative, which received the 2006 Pulitzer Prize for history, covers all the challenges, characters, and controversies in America's relentless struggle against polio. Funded by philanthropy and grassroots contributions, Salk's killed-virus vaccine (1954) and Sabin's live-virus vaccine (1961) began to eradicate this dreaded disease.

Medical Apartheid is the first and only comprehensive history of medical experimentation on African Americans. Starting with the earliest encounters between black Americans and Western medical researchers and the racist pseudoscience that resulted, it details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge - a tradition that continues today within some black populations.

Norman Lebrecht has devoted half of his life to pondering and researching the mindset of the Jewish intellectuals, writers, scientists, and thinkers who turned the tides of history and shaped the world today as we know it. In Genius & Anxiety, Lebrecht begins with the Communist Manifesto in 1847 and ends in 1947, when Israel was founded. This robust, magnificent volume, beautifully designed, is an urgent and necessary celebration of Jewish genius and contribution.