Regarded as one of the finest journalists of her generation, Mamie Baird Magnusson's whole life was a celebration of words - words that she fought to retain in the grip of a disease which is fast becoming the scourge of the 21st century. Married to writer and broadcaster Magnus Magnusson, they had five children of whom Sally is the eldest.

Gadsby grew up as the youngest of five children in Tasmania, where homosexuality was illegal until 1997. After moving to mainland Australia and receiving a degree in art history, they found themselves adrift, working itinerant jobs and enduring years of isolation punctuated by homophobic and sexual violence. When Gadsby was twenty-seven, a friend encouraged them to enter a stand-up competition. They won, and so began their career in comedy.

Rachel Jenner is walking in a Bristol park with her eight-year-old son, Ben, when he asks if he can run ahead. It's an ordinary request on an ordinary Sunday afternoon, and Rachel has no reason to worry - until Ben vanishes. Police are called, search parties go out, and Rachel, already insecure after her recent divorce, feels herself coming undone. As hours and then days pass without a sign of Ben, everyone who knew him is called into question, from Rachel's newly married ex-husband to her mother-of-the-year sister.

They all thought he was gone. But he was alive and trapped inside his own body for ten years. In January 1988 Martin Pistorius, aged 12, fell inexplicably sick. First, he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within 18 months, he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.

Wendy Mitchell had a busy job with the British National Health Service, raised her two daughters alone, and spent her weekends running and climbing mountains. Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn’t know it then, but dementia was starting to take hold. In 2014, at age 58, she was diagnosed with young-onset Alzheimer’s. In this groundbreaking book, Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off.

From childhood, Laura James knew she was different. She struggled to cope in a world that often made no sense to her, as though her brain had its own operating system. It wasn't until she reached her 40s that she found out why: Suddenly and surprisingly, she was diagnosed with autism. With a touching and searing honesty, Laura challenges everything we think we know about what it means to be autistic. Married with four children and a successful journalist, Laura examines the ways in which autism has shaped her career, her approach to motherhood, and her closest relationships.

When the partner of Emmy Award–winning screenwriter Abi Morgan abruptly collapsed from a mysterious illness, doctors were concerned that he would not survive. Then, six months later, Jacob woke from his coma, to the delight and relief of his family and friends—except this proved to be anything but a Hollywood ending. Because to Jacob, the woman standing at his bedside, who had cared for him all these months, was not his partner. Not his children’s mother. Not the woman he loved. Sure, she looked like his Abi, but this was an imposter, living someone else’s life.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

One morning in late 2017, New York Times columnist Frank Bruni woke up with strangely blurred vision. He wondered at first if some goo or gunk had worked its way into his right eye. But this was no fleeting annoyance, no fixable inconvenience.

New York Times best-selling author Ian McEwan's novels have inspired sweeping critical acclaim and won such prestigious awards as the Booker Prize for Amsterdam and the National Book Critics Circle Award for his modern masterpiece, Atonement. With Saturday, McEwan has crafted perhaps his most unique achievement to date.

The new novel by the author of the best-selling The World Walker series. 'My name is Daniel Harbin, and I'm a child of The Deterrent.' What if a superhuman turned out not to be so super...or even human? Britain's superhero, The Deterrent, was unveiled to the world in 1979 and disappeared two years later. The truth about his origins has never been revealed. The rumours about his children - those that survived - and their mysterious abilities have never been confirmed. Until now....

Best friends Noah Sadler and Abdi Mahad have always been inseparable. But when Noah is found floating unconscious in Bristol's Feeder Canal, Abdi can't - or won't - tell anyone what happened. Just back from a mandatory leave following his last case, Detective Jim Clemo is now assigned to look into this unfortunate accident. But tragedy strikes, and what looked like the simple case of a prank gone wrong soon ignites into a public battle. Noah is British. Abdi is a Somali refugee. And social tensions have been rising rapidly in Bristol.

Each of the Maguire brothers has his own driving, single-minded obsession. For Jonathan it is his magnificent, talented, and desirable wife, Harriet. For Roger it is the elaborate universe he has constructed in a shed in their parents' garden, populated by millions of tiny insects. While Jonathan's pursuit of Harriet leads him to feelings of jealousy and anguish, Roger's immersion in the world he has created reveals a capability and talent that are absent from his everyday life.

Hurry Down Sunshine tells the story of the extraordinary summer when, at the age of 15, Michael Greenberg's daughter was struck mad. It begins with Sally's sudden visionary crack-up on the streets of Greenwich Village, and continues, among other places, in the out-of-time world of a Manhattan psychiatric ward during the city's most sweltering months.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

Lauren Marks was 27 when an aneurysm ruptured in her brain and left her fighting for her life. She woke up in a hospital soon after with serious deficiencies to her reading, speaking, and writing abilities, and an unfamiliar diagnosis: aphasia. This would be shocking news for anyone, but Lauren was a voracious reader, an actress, director, dramaturg, and pursuing her PhD. At any other period of her life, this diagnosis would have been a devastating blow. But she woke up...different.

From the moment Martha and her husband, John, conceived their second child, all hell broke loose. They were a couple obsessed with success. After years of matching IQs and test scores with less driven peers, they had two Harvard degrees apiece and were gunning for more. But the dream had begun to disintegrate. Then, when their unborn son, Adam, was diagnosed with Down syndrome, doctors, advisers, and friends in the Harvard community warned them not to keep the baby.

Nine-year-old Louis Drax lies in a coma in a hospital bed, re-living the events that led to his near-fatal fall into a ravine. Despite being attracted to the boy's mother Natalie Drax, Louis' doctor, Pascal Dannachet, begins reluctantly to question her version of Louis' accident and the apparent culpability of her missing husband. As the boy struggles to communicate from within his coma, the chilling truth emerges....

In anticipation of her 38th birthday, Katherine May set out to walk the 630-mile South West Coast Path. She wanted time alone, in nature, to understand why she had stopped coping with everyday life; why motherhood had been so overwhelming and isolating; and why the world felt full of expectations she couldn't meet. She was also reeling from a chance encounter with a voice on the radio that sparked her realisation that she might be autistic.

The new novel by the author of the best-selling The World Walker series. 'My name is Daniel Harbin, and I'm a child of The Deterrent.' What if a superhuman turned out not to be so super...or even human? Britain's superhero, The Deterrent, was unveiled to the world in 1979 and disappeared two years later. The truth about his origins has never been revealed. The rumours about his children - those that survived - and their mysterious abilities have never been confirmed. Until now....

When Amy B. Scher was struck with undiagnosed late-stage, chronic Lyme disease, the best physicians in America labeled her condition incurable and potentially terminal. Deteriorating rapidly, she went on a search to save her own life - from the top experts in Los Angeles and the world-renowned Mayo Clinic in Minneapolis to a state-of-the-art hospital in Chicago. After exhausting all of her options in the US, she discovered a possible cure - but it was highly experimental, available only in India, and had as much of a probability of killing her as it did of curing her.

In a narrative that spans geography and time, from the Atlantic Ocean in the 17th century to a correctional institute in Texas in the near future, and told from the perspectives of five very different characters, Speak considers what it means to be human and what it means to be less than fully alive.

Brainstorm follows the stories of people whose medical diagnoses are so strange even their doctor struggles to know how to solve them. A man who sees cartoon characters running across the room; a girl whose world suddenly seems completely distorted, as though she were Alice in Wonderland; another who transforms into a ragdoll whenever she even thinks about moving. The brain is the most complex structure in the universe. Neurologists must puzzle out life-changing diagnoses from the tiniest of clues, the ultimate medical detective work.

An undeciphered language in Crete. A rash of mysterious disappearances, from Bolivia to Japan. An ancient warning at the ruins of Babel. And a new spiritual leader, who claims that human history as we understand it is about to come to an end.

In 2015, Barbara Lipska - a leading expert on the neuroscience of mental illness - was diagnosed with melanoma that had spread to her brain. Within months, her frontal lobe, the seat of cognition, began shutting down. She descended into madness, exhibiting dementia- and schizophrenia-like symptoms that terrified her family and coworkers. But miraculously, the immunotherapy her doctors had prescribed worked quickly. Just eight weeks after her nightmare began, Lipska returned to normal. With one difference: she remembered her brush with madness with exquisite clarity.

Dr Cat Lupo aches for another child despite the psychosis which marked her first pregnancy. So when Ruby Winter, a small girl in need of help, arrives in the middle of the night, it seems like fate. But as the events behind Ruby's arrival emerge - her mother's death, her connection to Cat - Cat questions whether her decision to help Ruby has put her own daughter at risk.

When Schuyler Rummel-Hudson was 18 months old, a question about her lack of speech by her pediatrician set in motion a journey that continues today. When she was diagnosed with bilateral perisylvian polymicrogyria (an extremely rare neurological disorder), her parents were given a name for the monster that had been stalking them from doctor to doctor, and from despair to hope, and back again.

Ghostbelly is Elizabeth Heineman’s personal account of a home birth that goes tragically wrong—ending in a stillbirth—and the harrowing process of grief and questioning that follows. It’s also Heineman’s unexpected tale of the loss of a newborn: before burial, she brings the baby home for overnight stays.

In "Books and Roses", one special key opens a library, a garden, and clues to at least two lovers' fates. In "Is Your Blood as Red as This?", an unlikely key opens the heart of a student at a puppeteering school. "'Sorry' Doesn't Sweeten Her Tea" involves a "house of locks", where doors can be closed only with a key - with surprising unobservable developments. And in "If a Book Is Locked There's Probably a Good Reason for That Don't You Think", a key keeps a mystical diary locked (for good reason).

Robert Charles Wilson, says The New York Times, "writes superior science fiction thrillers." His Darwinia won Canada's Aurora Award; his most recent novel, The Chronoliths, won the prestigious John W. Campbell Memorial Award. Now he tells a gripping tale of alien contact and human love in a mysterious but hopeful universe.