As a psychiatrist in training fresh from medical school, Carl Erik Fisher found himself face-to-face with an addiction crisis that nearly cost him everything. Desperate to make sense of his condition, he turned to the history of addiction, learning that our society’s current quagmire is only part of a centuries-old struggle to treat addictive behavior.

The world's largest land mammal could help us end cancer. The fastest bird is showing us how to solve a century-old engineering mystery. The oldest tree is giving us insights into climate change. The loudest whale is offering clues about the impact of solar storms. For a long time, scientists ignored superlative life forms as outliers. Increasingly, though, researchers are coming to see great value in studying plants and animals that exist on the outermost edges of the bell curve.

While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.

Keeping skin healthy is a booming industry, and yet it seems like almost no one agrees on what actually works. What one person says is vital another says is toxic. We have not cured acne or eczema, allergies keep getting worse, and autoimmune conditions are becoming increasingly common. In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today.

Drawing upon the author's two decades teaching medical ethics, as well as his work as a practicing psychiatrist, this profound and addictive little book offers up challenging ethical dilemmas and asks listeners, What would you do? In short, engaging scenarios, Dr. Appel takes on hot-button issues that many of us will confront: genetic screening, sexuality, privacy, doctor-patient confidentiality. He unpacks each hypothetical with a brief reflection drawing from science, philosophy, and history, explaining how others have approached these controversies in real-world cases.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

It's 1913, and on the surface, Laura Lyons couldn't ask for more out of life - her husband is the superintendent of the New York Public Library, allowing their family to live in an apartment within the grand building, and they are blessed with two children. But headstrong, passionate Laura wants more, and when she takes a leap of faith and applies to the Columbia Journalism School, her world is cracked wide open.

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.

Why do minds exist? How did mud and stone develop into beings that can experience longing, regret, love, and compassion - beings that are aware of their own experience? Until recently, science offered few answers to these existential questions. Journey of the Mind is the first book to offer a unified account of the mind that explains how consciousness, language, the Self, and civilization emerged incrementally out of chaos.

Twenty thousand years ago, women were making and wearing the first clothing created from spun fibers. In fact, right up to the Industrial Revolution the fiber arts were an enormous economic force, belonging primarily to women. Despite the great toil required in making cloth and clothing, most books on ancient history and economics have no information on them. Much of this gap results from the extreme perishability of what women produced, but it seems clear that until now descriptions of prehistoric and early historic cultures have omitted virtually half the picture.

Bill Bryson once again proves himself to be an incomparable companion as he guides us through the human body - how it functions, its remarkable ability to heal itself, and (unfortunately) the ways it can fail. Full of extraordinary facts (your body made a million red blood cells since you started reading this) and irresistible Bryson-esque anecdotes, The Body will lead you to a deeper understanding of the miracle that is life in general and you in particular. As Bill Bryson writes, "We pass our existence within this wobble of flesh and yet take it almost entirely for granted."

A child holds the hand of his dying mother and is terrified, aware something is taking her. Orphaned and given to an itinerant barber-surgeon, Rob Cole becomes a fast-talking swindler, peddling a worthless medicine. But as he matures, his strange gift - an acute sensitivity to impending death - never leaves him, and he yearns to become a healer. Arab madrassas are the only authentic medical schools, and he makes his perilous way to Persia.

Award-winning historian Michael Wallis has spent several years re-creating the rich, anecdotal saga of Billy the Kid (1859-1881), a deeply mythologized young man who became a legend in his own time and yet remains an enigma to this day. With the Gilded Age in full swing and the Industrial Revolution reshaping the American landscape, "the Kid", who was gunned down by Sheriff Pat Garrett in the New Mexico Territory at the age of 21, became a new breed of celebrity outlaw.

Charlotte Gordon's new work is a fresh look at the lives of Mary Wollstonecraft and Mary Shelley, who together comprise one of the most illustrious and inspiring mother-daughter pairs in history.

In the 1860s, Napoleon III, intent on curbing the rise of American imperialism, persuaded a young Austrian archduke and a Belgian princess to leave Europe and become the emperor and empress of Mexico. They and their entourage arrived in a Mexico ruled by terror, where revolutionary fervor was barely suppressed by French troops. When the United States, now clear of its own Civil War, aided the rebels in pushing back Maximilian’s imperial soldiers, the French army withdrew, abandoning the young couple. The regime fell apart.

Best-selling author Mary Roach returns with a new adventure to the invisible realm we carry around inside. Roach takes us down the hatch on an unforgettable tour. The alimentary canal is classic Mary Roach terrain: The questions explored in Gulp are as taboo, in their way, as the cadavers in Stiff and every bit as surreal as the universe of zero gravity explored in Packing for Mars. Why is crunchy food so appealing? Why is it so hard to find words for flavors and smells? Why doesn’t the stomach digest itself? How much can you eat before your stomach bursts?

Interesting anecdotes and engaging tales make science fun, meaningful, and accessible. Separating sense from nonsense and fact from myth, these essays cover everything from the ups of helium to the downs of drain cleaners and provide answers to numerous mysteries, such as why bug juice is used to color ice cream and how spies used secret inks. Mercury in teeth, arsenic in water, lead in the environment, and aspartame in food are discussed.

Just when you thought that it was safe to start showing off again, John Lloyd and John Mitchinson are back with another busload of mistakes and misunderstandings. Here is a new collection of simple, perfectly obvious questions you'll be quite certain you know the answers to. Whether it's history, science, sports, geography, literature, language, medicine, the classics, or common wisdom, you'll be astonished to discover that everything you thought you knew is still hopelessly wrong.

In Proof, Adam Rogers reveals alcohol as a miracle of science, going deep into the pleasures of making and drinking booze—and the effects of the latter. The people who make and sell alcohol may talk about history and tradition, but alcohol production is really powered by physics, molecular biology, organic chemistry, and a bit of metallurgy—and our taste for those products is a melding of psychology and neurobiology.

A wide-ranging and provocative look - teeming with little-known facts and engaging stories - at a subject of the direst interest. Poisons permeate our world. They are in the environment, the workplace, the home. They are in food, our favorite whiskey, medicine, well water. They have been used to cure disease as well as incapacitate and kill. They smooth wrinkles, block pain, stimulate, and enhance athletic ability. In this entertaining and fact-filled audiobook, science writer Peter Macinnis considers poisons in all their aspects. He recounts stories of the celebrated poisoners in history and literature....

Guns, germs, and steel might have transformed us from hunter-gatherers into modern man, but booze, sex, trash talk, and tripping built our civilization. Cracked editor Robert Evans brings his signature dogged research and lively insight to uncover the many and magnificent ways vice has influenced history, from the prostitute-turned-empress who scored a major victory for women's rights to the beer that helped create - and destroy - South America's first empire.

Wondering whether eating powdered mummies might be just the thing to cure your ills? Tempted by those vintage ads suggesting you wear radioactive underpants for virility? Ever considered drilling a hole in your head to deal with those pesky headaches? Probably not. But for thousands of years, people have done things like this - and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.

Grunt tackles the science behind some of a soldier's most challenging adversaries - panic, exhaustion, heat, noise - and introduces us to the scientists who seek to conquer them. Mary Roach dodges hostile fire with the U.S. Marine Corps Paintball Team as part of a study on hearing loss and survivability in combat. She visits the fashion design studio of U.S. Army Natick Labs and learns why a zipper is a problem for a sniper.

In Mycophilia, accomplished food writer and cookbook author Eugenia Bone examines the role of fungi as exotic delicacy, curative, poison, and hallucinogen, and ultimately discovers that a greater understanding of fungi is key to facing many challenges of the 21st century.

There is nothing more essential to our health and well-being than breathing. Yet, as a species, humans have lost the ability to breathe correctly, with grave consequences. Journalist James Nestor travels the world to figure out what went wrong and how to fix it. The answers aren’t found in pulmonology labs, as we might expect, but in the muddy digs of ancient burial sites, secret Soviet facilities, New Jersey choir schools, and the smoggy streets of São Paulo. Nestor tracks down men and women exploring the hidden science behind ancient breathing practices.

Can urban farms reduce neighborhood crime? These may not sound like typical questions for a family physician to consider, but in Farmacology, Daphne Miller, MD, ventures out of her medical office and travels to seven innovative family farms around the country on a quest to discover the hidden connections between how we care for our bodies and how we grow our food. Miller also seeks out the perspectives of noted biomedical scientists and artfully weaves in their research, along with stories from her own practice. Farmacology offers a profound new approach to healing.

Biomimicry is rapidly transforming life on earth. Biomimics study nature's most successful ideas over the past 3.5 million years, and adapt them for human use. The results are revolutionizing how materials are invented and how we compute, heal ourselves, repair the environment, and feed the world. Janine Benyus takes listeners into the lab and in the field with maverick thinkers as they: discover miracle drugs by watching what chimps eat when they're sick; learn how to create by watching spiders weave fibers; and many more examples.

A riveting investigation of the myriad ways that parasites control how other creatures - including humans - think, feel, and act. These tiny organisms can live only inside another animal, and, as McAuliffe reveals, they have many evolutionary motives for manipulating their host's behavior. Far more often than appreciated, these puppeteers orchestrate the interplay between predator and prey.

Once literally demonized as "the Devil's lettuce" and linked to all manner of deviant behavior by the establishment's shameless antimarijuana propaganda campaigns, Cannabis sativa has lately been enjoying a long-overdue Renaissance. So now that the squares at long last seem ready to rethink pot's place in polite society, how, exactly, can members of this vibrant, innovative, life-affirming culture proudly and properly emerge from the underground - without forgetting our roots or losing our cool?

In What Makes Olga Run? Bruce Grierson explores what the wild success of a 94-year-old track star can tell us about how our bodies and minds age. Olga Kotelko is not your average 94-year-old. She not only looks and acts like a much younger woman, she holds over 23 world records in track and field, 17 in her current 90 to 95 category. Convinced that this remarkable woman could help unlock many of the mysteries of aging, Grierson set out to uncover what it is that's driving Olga.