While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.

You wake up and feel a tickle in your throat. Your head hurts. You’re mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door. So what, exactly, is your immune system? In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes listeners on a journey through the fortress of the human body and its defenses.

Money - investing, personal finance, and business decisions - is typically taught as a math-based field, where data and formulas tell us exactly what to do. But in the real world people don’t make financial decisions on a spreadsheet. They make them at the dinner table, or in a meeting room, where personal history, your own unique view of the world, ego, pride, marketing, and odd incentives are scrambled together. In The Psychology of Money, award-winning author Morgan Housel shares 19 short stories exploring the strange ways people think about money.

An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable. Psychiatrist and psychoanalyst, Norman Doidge, MD, traveled the country to meet both the brilliant scientists championing neuroplasticity and the people whose lives they've transformed - people whose mental limitations or brain damage were seen as unalterable.

Stephen Hawking not only unraveled some of the universe's greatest mysteries but also believed science plays a critical role in fixing problems here on Earth. Now, as we face immense challenges on our planet - including climate change, the threat of nuclear war, and the development of artificial intelligence - he turns his attention to the most urgent issues facing us. Will humanity survive? Should we colonize space? Does God exist? These are just a few of the questions Hawking addresses in this wide-ranging, passionately argued final book from one of the greatest minds in history.

The millions of people around the world who loved What If? still have questions, and those questions are getting stranger. Thank goodness xkcd creator Randall Munroe is here to help. Planning to ride a fire pole from the Moon back to Earth? The hardest part is sticking the landing. Hoping to cool the atmosphere by opening everyone’s freezer door at the same time? Maybe it’s time for a brief introduction to thermodynamics. Want to know what would happen if you rode a helicopter blade, made a lava lamp out of lava, or jumped on an erupting geyser? Okay, if you insist.

The world's largest land mammal could help us end cancer. The fastest bird is showing us how to solve a century-old engineering mystery. The oldest tree is giving us insights into climate change. The loudest whale is offering clues about the impact of solar storms. For a long time, scientists ignored superlative life forms as outliers. Increasingly, though, researchers are coming to see great value in studying plants and animals that exist on the outermost edges of the bell curve.

In The Patient Will See You Now, Eric Topol, one of the nation's top physicians, examines what he calls medicine's "Gutenberg moment". Much as the printing press liberated knowledge from the control of an elite class, new technology is poised to democratize medicine. In this new era, patients will control their data and be emancipated from a paternalistic medical regime in which "the doctor knows best."

One of the world's most renowned theoretical physicists, Carlo Rovelli has entranced millions of readers with his singular perspective on the cosmos. In Helgoland, he examines the enduring enigma of quantum theory. The quantum world Rovelli describes is as beautiful as it is unnerving. Helgoland is a treeless island in the North Sea where the 23-year-old Werner Heisenberg made the crucial breakthrough for the creation of quantum mechanics, setting off a century of scientific revolution.

Before the internet became widely known as a global tool for terrorists, one perceptive US citizen recognized its ominous potential. Armed with clear evidence of computer espionage, he began a highly personal quest to expose a hidden network of spies that threatened national security. But would the authorities back him up? Cliff Stoll's dramatic firsthand account is "a computer-age detective story, instantly fascinating [and] astonishingly gripping" - Smithsonian.

The solution to your food and weight problems isn't willpower or the next fad diet - it's breaking up with sugar. Molly Carmel, an eating disorder therapist with a thriving clinic in New York City, discovered the devastating role sugar played in her own 20-year struggle with disordered eating. Molly has since helped thousands of people overcome compulsive overeating, repetitive dieting, and sugar addiction to reinvent their lives. Here, she shares her empowering 66-day blueprint for kicking sugar to the curb - once and for all.

As a psychiatrist in training fresh from medical school, Carl Erik Fisher found himself face-to-face with an addiction crisis that nearly cost him everything. Desperate to make sense of his condition, he turned to the history of addiction, learning that our society’s current quagmire is only part of a centuries-old struggle to treat addictive behavior.

Drawing upon the author's two decades teaching medical ethics, as well as his work as a practicing psychiatrist, this profound and addictive little book offers up challenging ethical dilemmas and asks listeners, What would you do? In short, engaging scenarios, Dr. Appel takes on hot-button issues that many of us will confront: genetic screening, sexuality, privacy, doctor-patient confidentiality. He unpacks each hypothetical with a brief reflection drawing from science, philosophy, and history, explaining how others have approached these controversies in real-world cases.

This fascinating book draws on Dr. Jandial's broad-spectrum expertise and brings together the best of various fields - surgery, science, brain structure, the conscious mind - all to explain the bigger picture of brain health and rejuvenation. It is a journey into his operating room, around the world on his surgical missions, inside his laboratory, and to the outer edges of neuroscience to reveal the latest brain breakthroughs that are turning science fiction into reality, translating their implications for everyday life.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

The human brain is perhaps the most powerful and mysterious arrangement of matter in the known universe. New discoveries that unravel this mystery and let us tap into this power offer almost limitless potential - the ability to reshape ourselves and our thought processes, to improve our health and extend our lives, and to enhance and augment the ways we interact with the world around us. In The NeuroGeneration, award-winning inventor Tan Le explores exciting advancements in brain science and neurotechnology that are revolutionizing the way we think, work, and heal.

A scientific and medical revolution has crept up on us, based on study after study, from hundreds of laboratories around the world. It is no longer just a theoretical shift: every one of us will be touched by it, and many of us already have been. The meaning of disease, our understanding of the human body, and crucial decisions about what we all need to know and what choices we make about our health are at stake. Welcome to the new world of personalized medicine.

The author of the highly acclaimed Overdiagnosed describes seven widespread assumptions that encourage excessive, often ineffective, and sometimes harmful medical care. You might think the biggest problem in medical care is that it costs too much. Or that health insurance is too expensive, too uneven, too complicated - and gives you too many forms to fill out. But the central problem is that too much medical care has too little value.

In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. Sixteen million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their 70s and 80s, the number of patients will rise to an estimated 13.8 million by 2025. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis.

Drawing on 40 years of research and patient care, Dr. Wayne Jonas explains how 80 percent of healing occurs organically and how to activate the healing process. In How Healing Works, Dr. Wayne Jonas lays out a revolutionary new way to approach injury, illness, and wellness. Dr. Jonas explains the biology of healing and the science behind the discovery that 80 percent of healing can be attributed to the mind-body connection and other naturally occurring processes. Jonas details how the healing process works and what we can do to facilitate our own innate ability to heal.

If we could turn back the clock psychologically, could we also turn it back physically? For more than 30 years, award-winning social psychologist Ellen Langer has studied this provocative question, and now has a conclusive answer: opening our minds to what's possible, instead of clinging to accepted notions about what's not, can lead to better health at any age.

Published in partnership with the International Association for the Study of Pain, A Nation in Pain offers a sweeping, deeply researched account of the chronic pain crisis, from neurobiology to public policy, and presents practical solutions that are within our grasp today. Drawing on both her personal experience with chronic pain and her background as an award-winning health journalist, she guides us through recent scientific discoveries, including genetic susceptibility to pain.

Cancer strikes fear in people’s hearts around globe. So the appearance of a vaccine to prevent cancer - as we are assured the human papillomavirus (HPV) vaccine will - seemed like a game-changer. Since 2006, over 80 countries have approved the vaccine, with glowing endorsements from the world’s foremost medical authorities. Bringing in over $2.5 billion in annual sales, the HPV vaccine is a pharmaceutical juggernaut. Yet scandal now engulfs it worldwide. The HPV Vaccine on Trial is a shocking tale, chronicling the global efforts to sell and compel this alleged miracle.

Dr. Marty Makary is co-developer of the life-saving checklist outlined in Atul Gawande's best-selling The Checklist Manifesto. As a busy surgeon who has worked in many of the best hospitals in the nation, he can testify to the amazing power of modern medicine to cure. But he's also been a witness to a medical culture that routinely leaves surgical sponges inside patients, amputates the wrong limbs, and overdoses children because of sloppy handwriting. Over the last 10 years, neither error rates nor costs have come down, despite scientific progress.

On average, a physician will interrupt a patient describing her symptoms within 12 seconds. In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong: with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Moneyball meets medicine in this remarkable chronicle of one of the greatest scientific quests of our time - the groundbreaking program to answer the most essential question for humanity: How do we live and die? - and the visionary mastermind behind it.

Today, number crunching affects your life in ways you might never imagine. In this lively and groundbreaking new audiobook, economist Ian Ayres shows how today's best and brightest organizations are analyzing massive databases at lightening speed to provide greater insights into human behavior. They are the Super Crunchers.

Melding neuroscience with narrative, science journalist David Robson takes lstenersi on a deep dive into the many life zones the expectation effect permeates. We see how people who believe stress is beneficial become more creative when placed under strain. We see how associating aging with wisdom can add seven plus years to your life. People say seeing is believing but, over and over, Robson proves that the converse is truer: Believing is seeing.

Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.

In The Patient Will See You Now, Eric Topol, one of the nation's top physicians, examines what he calls medicine's "Gutenberg moment". Much as the printing press liberated knowledge from the control of an elite class, new technology is poised to democratize medicine. In this new era, patients will control their data and be emancipated from a paternalistic medical regime in which "the doctor knows best."

Just months ago, millions of people were stunned by ChatGPT's amazing abilities–and its bizarre hallucinations. But that was 2022. GPT-4 is now here, with smarter, more accurate, and deeper technical knowledge. GPT-4 and its competitors and followers are on the verge of transforming medicine. But with lives on the line, you need to understand these technologies–stat.

Do you know what AI is doing to improve our health and well-being? Does this new technology concern you, or impress you? Do you want to know more about the future of AI in health care? Technology continues to advance at a pace that can seem bewildering. Nowhere else is it moving faster than in the health sector, where AI is now being used to improve millions of lives. In this audiobook, Artificial Intelligence in Healthcare: AI, Machine Learning, and Deep and Intelligent Medicine Simplified for Everyone, you can discover the great improvements that AI is making.

Until very recently, if you were to ask most doctors, they would tell you there were only two kinds of medicine: the quack kind, and the evidence-based kind. The former is baseless, and the latter based on the best information human effort could buy. Well, Eric Topol isn't most doctors, and he suggests you entertain the notion of a third kind of medicine, one that will make the evidence-based state-of-the-art stuff look scarcely better than an alchemist trying to animate a homunculus in a jar.

A renowned cardiologist and Harvard professor spells out the future digital shift of medicine—and how it will impact the lives not only of patients and health care professionals but of all humans.

This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals.

High-tech innovations are created at a dazzling speed, and it all points to a world that is getting faster at a dizzying pace. Azeem Azhar knows this better than most. Over the last three decades, he has founded companies bought by Amazon and Microsoft, served as the Economist’s first ever internet correspondent, and created a leading international tech newsletter and podcast, the Exponential View. Now, Azhar offers a revelatory new model for understanding how technology is changing the world.

Unlock the Power of First Principles Thinking: Transform Your Problem-Solving and Innovate Like History's Greatest Minds Are you ready to revolutionize the way you approach challenges and unleash your innovative potential? Dive into the world of first principles thinking with this groundbreaking guide that will transform your problem-solving skills and ignite your creativity. From the Wright brothers' conquest of the skies to Elon Musk's disruption of multiple industries, first principles thinking has been the secret weapon of history's most brilliant innovators. Now, it's your turn to ...

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.

Artificial intelligence powers Google's search engine, enables Facebook to target advertising, and allows Alexa and Siri to do their jobs. AI is also behind self-driving cars, predictive policing, and autonomous weapons that can kill without human intervention. These and other AI applications raise complex ethical issues that are the subject of ongoing debate. This volume in the MIT Press Essential Knowledge series offers an accessible synthesis of these issues.