Bethany can’t wait for the end of her hospital shift – four glorious days of relaxation await. Secretly, she’s most excited about the fun-filled nights reveling in an unexpected flirtation with her co-worker, Michelle. Thoughts of her long, cozy weekend vanish, however, when Francisco Delgado is admitted to her floor from the emergency room. Delgado, a man who came into contact with an unknown arachnid species in South America, and who now has something…squirming…beneath his skin.

Years after escaping the grip of a sinister cult, Rachel Miller thought she had left the past behind. But when a strange man with a faded photograph shows up asking questions, old nightmares return—visions of blood-soaked ceremonies, cryptic symbols, and an ancient presence buried deep underground. A familiar voice whispers in the back of her mind, urging her to return to her brothers and sisters to finish the ritual they began so many years ago.

An alcoholic teacher and father’s world spirals out of control when a former student is killed and he is left with her dog and the dark presence that follows it. Matt Matheny teaches during the day, drinks at night, and barely hides his functioning alcoholism from his veterinarian ex-wife, Lucy, and his six-year-old son, Mikey. His world spirals out of control when a former student is killed, and he's left with her dog, Conehead. But something isn't right with Conehead.

Fueled by online trends, a shift in the American zeitgeist has led to the instatement of the Lazarus Act, legalizing the 'recreational use' of human corpses. Ellis Mercer, recently bereaved, embarks on a secret mission to America's first 'necrotel' to recover his wife's remains, before her corpse and his memory of her are desecrated by the motel’s twisted membership.

Bryan and Ellie Stockton hope they left behind their demons when they move to their idyllic new home in southern West Virginia. Above all, they want a fresh start for their young son, Derrick, who witnessed the tumultuous first years of their marriage—years that were rife with substance abuse, rage, and resentment. Their bright hope for the future is darkened when a child disappears from their neighborhood. The couple becomes suspicious of a reclusive resident with a degenerative brain disorder.