Throughout history, every age has thought of itself as more knowledgeable than the last. Renaissance humanists viewed the Middle Ages as an era of darkness, Enlightenment thinkers tried to sweep superstition away with reason, the modern welfare state sought to slay the “giant” of ignorance, and in today’s hyperconnected world seemingly limitless information is available on demand. But what about the knowledge lost over the centuries? Are we really any less ignorant than our ancestors?

Nearly seven million Americans live with Alzheimer’s disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller’s Doctored shows that we’ve quite likely been walking the wrong path to finding a cure all along—led astray by a cabal of self-interested researchers, government accomplices, and corporate greed.

Medical Apartheid is the first and only comprehensive history of medical experimentation on African Americans. Starting with the earliest encounters between black Americans and Western medical researchers and the racist pseudoscience that resulted, it details the ways both slaves and freedmen were used in hospitals for experiments conducted without their knowledge - a tradition that continues today within some black populations.

A groundbreaking, sweeping overview of the great kingdoms in African history and their legacies, written by world-leading experts.

Americans are caught up in bulk. We guiltily watch Amazon boxes pile up on the porch, wade through endless reviews to find the perfect product, and crave the comforting indulgence of a chain restaurant. In American Bulk, Emily Mester intertwines cultural critique and personal history to explore how the things we buy, eat, amass, and discard become an intimate part of our lives. With humor and sharp intellect, she reflects on the joys and anxieties of family Costco trips, how a seasonal stint at Ulta Beauty taught her the insidious art of the sale, and what it means to get Mall Sad.

In Blind Spots, Dr. Makary explores the latest research on critical topics ranging from the microbiome to childbirth to nutrition and longevity and more, revealing the biggest blind spots of modern medicine and tackling the most urgent yet unsung issues in our $4.5 trillion health care ecosystem. The path to medical mishaps can be absurd, entertaining, and jaw-dropping—but the truth is essential to our health.

Until the twentieth century, scientists investigating the effects of drugs on the mind did so by experimenting on themselves. Vivid descriptions of drug experiences sparked insights across the mind sciences, pharmacology, medicine, and philosophy. But after 1900 drugs were increasingly viewed as a social problem, and the long tradition of self-experimentation began to disappear. Mike Jay brilliantly recovers a lost intellectual tradition of drug-taking that fed the birth of psychology, the discovery of the unconscious, and the emergence of modernism.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.

From blurry vision to crooked teeth, ACLs that tear at alarming rates and spines that seem to spend a lifetime falling apart, it's a curious thing that human beings have beaten the odds as a species. After all, we're the only survivors on our branch of the tree of life. Why is it that human mothers have such a life-endangering experience giving birth? And why are there entire medical specialties for teeth and feet? In this funny, wide-ranging and often surprising book, biologist Alex Bezzerides tells us just where we inherited our achy, brilliant bodies in the process of evolution.

Being and Time was published in 1927 during the Weimar period in Germany, a time of political, social and economic turmoil. Heidegger himself did not escape the pressures and his nationalism, and undeniable anti-Semitism in the following decades cast a shadow over the man, but not the work. Being and Time is not coloured by expressions of his later views (unlike other writings) and remains an outstanding document.

In her memoir All That Remains, internationally renowned forensic anthropologist and human anatomist Dame Sue Black recounted her life lived eye to eye with the Grim Reaper. During the course of it, she offered a primer on the basics of identifying human remains, plenty of insights into the fascinating processes of death, and a sober, compassionate understanding of its inescapable presence in our existence. Now in this book, Black builds on that memoir, taking us on a guided tour of the human skeleton and explaining how each person's life history is revealed in their bones.

From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization - The Jungle for pharmaceuticals.

In 1971, Go Ask Alice reinvented the young adult genre with a blistering portrayal of sex, psychosis, and teenage self-destruction. The supposed diary of a middle-class addict, Go Ask Alice terrified adults and cemented LSD's fearsome reputation, fueling support for the War on Drugs. Five million copies later, Go Ask Alice remains a divisive bestseller, outraging censors and earning new fans, all of them drawn by the book's mythic premise: A Real Diary, by Anonymous.

The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out "war against cancer".

A crucial, clear-eyed assessment of what connects the two most influential moments of political violence in recent American history, and where we go from here.