
Doctored
Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
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Narrated by:
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Lyle Blaker
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By:
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Charles Piller
About this listen
An Economist Best Book of 2025 So Far
For fans of Empire of Pain and Dopesick, a “gripping story of medical groupthink and warped incentives” (The Economist) that follows how Alzheimer’s disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma.
Nearly seven million Americans live with Alzheimer’s disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller’s Doctored shows that we’ve quite likely been walking the wrong path to finding a cure all along—led astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
In this “riveting must-read master class in science journalism” (Gary Taubes, author of Rethinking Diabetes), Piller begins with a whistleblower—Vanderbilt professor Matthew Schrag—whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize–rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease.
Piller uncovers evidence that hundreds of important Alzheimer’s research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field’s institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. Piller “masterfully unfolds an epic tale of astounding fraud, scientific egos run amok, and steely heroism in the pursuit of truth, creating both a page-turner and a seminal account of deceit that will long be remembered alongside Theranos and Enron as a scandal for the ages” (Katherine Eban, author of Bottle of Lies).
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Science Fictions
- How Fraud, Bias, Negligence, and Hype Undermine the Search for Truth
- By: Stuart Ritchie
- Narrated by: Stuart Ritchie
- Length: 8 hrs and 35 mins
- Unabridged
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Science is how we understand the world. Yet failures in peer review and mistakes in statistics have rendered a shocking number of scientific studies useless—or, worse, badly misleading. Such errors have distorted our knowledge in fields as wide-ranging as medicine, physics, nutrition, education, genetics, economics, and the search for extraterrestrial life. As Science Fictions makes clear, the current system of research funding and publication not only fails to safeguard us from blunders but actively encourages bad science—with sometimes deadly consequences.
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Needed Now More Than Ever
- By Todd on 08-06-20
By: Stuart Ritchie
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How to Feed the World
- The History and Future of Food
- By: Vaclav Smil
- Narrated by: Joe Jameson
- Length: 7 hrs and 30 mins
- Unabridged
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We have never had to feed as many people as we do today. And yet, we misunderstand the essentials of where our food really comes from, how our dietary requirements shape us, and why this impacts our planet in drastic ways. As a result, in our economic, political, and everyday choices, we take for granted and fail to prioritize the thing that makes all our lives possible: food. In this ambitious, myth-busting book, Smil investigates many of the burning questions facing the world today.
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lots of dense information, hard to absorb.
- By chris on 05-20-25
By: Vaclav Smil
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Our Dollar, Your Problem
- An Insider's View of Seven Turbulent Decades of Global Finance, and the Road Ahead
- By: Kenneth Rogoff
- Narrated by: Evan Sibley
- Length: 12 hrs and 56 mins
- Unabridged
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Drawing in part on his own experiences, including with policymakers and world leaders, Kenneth Rogoff animates the remarkable postwar run of the dollar—how it beat out the Japanese yen, the Soviet ruble, and the euro—and the challenges it faces today from crypto and the Chinese yuan, the end of reliably low inflation and interest rates, political instability, and the fracturing of the dollar bloc.
By: Kenneth Rogoff
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Follow the Science
- How Big Pharma Misleads, Obscures, and Prevails
- By: Sharyl Attkisson
- Narrated by: Sharyl Attkisson
- Length: 12 hrs and 25 mins
- Unabridged
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Follow the Science recounts, in exacting detail, how far the pharmaceutical industry and its supporters in medicine, media, and government will go to protect their profits. Attkisson provides shocking examples that reveal the disturbing callousness our government, public health officials, and top researchers are capable of when it comes to the most vulnerable among us. And she explains, in a graphic sense, how some of the most trusted within our society are willing to commit life-threatening ethics violations.
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True Investigative Reporting
- By Robert L. Phillips III on 09-17-24
By: Sharyl Attkisson
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The Art of Uncertainty
- How to Navigate Chance, Ignorance, Risk and Luck
- By: David Spiegelhalter
- Narrated by: David Spiegelhalter
- Length: 10 hrs and 51 mins
- Unabridged
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Renowned statistician David Spiegelhalter shows how we can become better at dealing with what we don't know to make smarter choices in a world so full of puzzling variables. In lucid, lively prose, Spiegelhalter guides us through the principles of probability, illustrating how they can help us think more analytically about everything from medical advice to sports to climate change forecasts.
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Terrific
- By Roger March on 04-01-25
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Ends of the Earth
- Journeys to the Polar Regions in Search of Life, the Cosmos, and Our Future
- By: Neil Shubin
- Narrated by: Fred Berman
- Length: 7 hrs and 43 mins
- Unabridged
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Renowned scientist Neil Shubin has made extraordinary discoveries by leading scientific expeditions to the sweeping ice landscapes of the Arctic and Antarctic. He’s survived polar storms, traveled in temperatures that can freeze flesh in seconds, and worked hundreds of miles from the nearest humans, all to deepen our understanding of our world. Written with infectious enthusiasm and irresistible curiosity, Ends of the Earth blends travel writing, science, and history in a book brimming with surprising and wonderful discoveries.
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Excellent scientific view of the poles
- By Prosanta Chakrabarty on 02-27-25
By: Neil Shubin
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Meltdown
- Greed, Scandal, and the Collapse of Credit Suisse
- By: Duncan Mavin
- Narrated by: Charles Armstrong
- Length: 8 hrs and 3 mins
- Unabridged
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Credit Suisse was a 166-year-old bastion of global banking. But a veneer of high-class service disguised a darker, much dirtier reality. From its sterile Zurich headquarters, Credit Suisse banked dictators and drug dealers, hid stolen Nazi gold, and helped corrupt bankers fleece the firm's own clients of billions of dollars. Its top executives oversaw a global operation that laundered money for autocrats; they hired spies to track one another through the cobbled streets of the Swiss financial capital; and they helped clients hide their money from the world's tax authorities.
By: Duncan Mavin
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Three Wild Dogs (and the Truth)
- A Memoir
- By: Markus Zusak
- Narrated by: Markus Zusak
- Length: 5 hrs and 28 mins
- Unabridged
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What happens when the Zusak family opens their home to three big, wild, street-hardened dogs—Reuben, more wolf than hound; Archer, blond, beautiful, destructive; and the rancorously smiling Frosty, who walks like a rolling thunderstorm? The answer can only be chaos: There are street fights, park fights, public shamings, property damages, injuries, hospital visits, wellness checks, pure comedy, shocking tragedy, and carnage that must be heard to be believed.
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Great story, quite the tear jerker
- By Lindsey Shultz on 02-27-25
By: Markus Zusak
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Waste Wars
- The Wild Afterlife of Your Trash
- By: Alexander Clapp
- Narrated by: Greg Lockett
- Length: 12 hrs and 46 mins
- Unabridged
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Dumps and landfills around the world are overflowing. Disputes about what to do with the millions of tons of garbage generated every day have given rise to waste wars waged almost everywhere you look. Some are border skirmishes. Others hustle trash across thousands of miles and multiple oceans. But no matter the scale, one thing is true about almost all of them: few people have any idea they're happening.
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Horrifying Exposé
- By HappyatHeart on 06-24-25
By: Alexander Clapp
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The Narrative Brain
- The Stories Our Neurons Tell
- By: Fritz Alwin Breithaupt PhD
- Narrated by: Brian Wiggins
- Length: 10 hrs and 4 mins
- Unabridged
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As humans, we think in stories—stories that allow us to feel and share emotions. In order for this phenomenon to work, our brains and the ways in which we tell stories must be attuned to each other. But how exactly does this happen? Tapping into the essence of thinking in stories, Fritz Breithaupt draws on the latest scientific research, including a retelling study (comparable to the telephone game) with more than 12,000 participants, and experiments in which ChatGPT functions as storyteller.
Misconduct is the antithesis of science
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Extremely thorough work
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A biased accounting of scientific bias
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A one-sided view of the Alzheimer’s field
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