Sally Milz is a sketch writer for The Night Owls, a late-night live comedy show that airs every Saturday. With a couple of heartbreaks under her belt, she’s long abandoned the search for love, settling instead for the occasional hook-up, career success, and a close relationship with her stepfather to round out a satisfying life. But when Sally’s friend and fellow writer Danny Horst begins dating Annabel, a glamorous actress who guest-hosted the show, he joins the not-so-exclusive group of talented but average-looking and even dorky men at the show.

Harriet and Wyn have been the perfect couple since they met in college—they go together like salt and pepper, honey and tea, lobster and rolls. Except, now—for reasons they’re still not discussing—they don’t. They broke up five months ago. And still haven’t told their best friends.

Malcolm Gephardt, handsome and gregarious longtime bartender at the Half Moon, has always dreamed of owning a bar. When his boss finally retires, Malcolm stretches to buy the place. He sees unquantifiable magic and potential in the Half Moon and hopes to transform it into a bigger success, but struggles to stay afloat. His smart and confident wife, Jess, has devoted herself to her law career. After years of trying for a baby, she is facing the idea that motherhood may not be in the cards for her. Like Malcolm, she feels her youth beginning to slip away and wonders how to reshape her future.

In the spring of 2020, Lara’s three daughters return to the family's orchard in Northern Michigan. While picking cherries, they beg their mother to tell them the story of Peter Duke, a famous actor with whom she shared both a stage and a romance years before at a theater company called Tom Lake. As Lara recalls the past, her daughters examine their own lives and relationship with their mother, and are forced to reconsider the world and everything they thought they knew.

Lauren and her family—lucky bastards—have been granted the use of a spectacular brownstone, teeming with history and dizzyingly unattractive '70s wallpaper. Adding to the home’s bohemian, grungy splendor is the bar occupying the basement, a (mostly) beloved dive called The Sweet Spot. Within days of moving in, Lauren discovers that she has already made an enemy in the neighborhood by inadvertently sparking the divorce of a couple she has never actually met.

William Waters grew up in a house silenced by tragedy, where his parents could hardly bear to look at him, much less love him—so when he meets the spirited and ambitious Julia Padavano in his freshman year of college, it’s as if the world has lit up around him. With Julia comes her family, as she and her three sisters are inseparable: Sylvie, the family’s dreamer, is happiest with her nose in a book; Cecelia is a free-spirited artist; and Emeline patiently takes care of them all.

Sadie Montgomery never saw what was coming . . . Literally! One minute she’s celebrating the biggest achievement of her life—placing as a finalist in the North American Portrait Society competition—the next she’s lying in a hospital bed diagnosed with a “probably temporary” condition known as face blindness. She can see, but every face she looks at is now a jumbled puzzle of disconnected features. Imagine trying to read a book upside down and in another language. This is Sadie’s new reality.

After a wild bet, gourmet grilled-cheese sandwich, and cuddle with a baby goat, Alexis Montgomery has had her world turned upside down. The cause: Daniel Grant, a ridiculously hot carpenter who’s ten years younger than her and as casual as they come—the complete opposite of sophisticated city-girl Alexis. And yet their chemistry is undeniable.

Nisha Cantor lives the globetrotting life of the seriously wealthy, until her husband announces a divorce and cuts her off. Nisha is determined to hang onto her glamorous life. But in the meantime, she must scramble to cope--she doesn’t even have the shoes she was, until a moment ago, standing in. That’s because Sam Kemp—in the bleakest point of her life—has accidentally taken Nisha’s gym bag. But Sam hardly has time to worry about a lost gym bag—she’s struggling to keep herself and her family afloat.

It’s fair to say that Maddie’s life in London is far from rewarding. With a mother who spends most of her time in Ghana (yet still somehow manages to be overbearing), Maddie is the primary caretaker for her father, who suffers from advanced stage Parkinson’s. At work, her boss is a nightmare and Maddie is tired of always being the only Black person in every meeting.

Seventeen-year-old Lenni Pettersson lives on the Terminal Ward at the Glasgow Princess Royal Hospital. Though the teenager has been told she’s dying, she still has plenty of living to do. Joining the hospital’s arts and crafts class, she meets the magnificent Margot, an 83-year-old, purple-pajama-wearing, fruitcake-eating rebel, who transforms Lenni in ways she never imagined. As their friendship blooms, a world of stories opens for these unlikely companions who, between them, have been alive for one hundred years.

Sixteen-year-old Frankie Budge—aspiring writer, indifferent student, offbeat loner—is determined to make it through yet another summer in Coalfield, Tennessee, when she meets Zeke, a talented artist who has just moved into his grandmother’s house and who is as awkward as Frankie is. Romantic and creative sparks begin to fly, and when the two jointly make an unsigned poster, shot through with an enigmatic phrase, it becomes unforgettable to anyone who sees it. The edge is a shantytown filled with gold seekers. We are fugitives, and the law is skinny with hunger for us.

An expert at keeping moving, with her trusty motorhome and faithful dog Muffin, Sophie has built her life around keeping her loves and loyalties to a minimum. Fabulous fifty-something Hattie Langford has kept her heart and past safely stored away too. But for reasons she’s only willing to share with a stranger, Hattie needs to tell the story her family has been hiding at Riverbend, their home in Sherwood Forest. There is a history of heartbreak and hurt that Hattie is now ready to face.

Gifted musician Clemency Thompson is playing for tourists on the streets of Southern France when she receives an urgent text message. Her childhood friend, Lucy, is demanding her immediate return to London. It’s happening, says the message. The baby is back. Libby Jones was only six months old when she became an orphan. Now 25, she’s astounded to learn of an inheritance that will change her life. A gorgeous, dilapidated townhouse in one of London’s poshest neighborhoods has been held in a trust for her all these years. Now, it’s hers.

Hallie Piper is turning over a new leaf. After belly-crawling out of a hotel room (hello, rock bottom), she decides it’s time to become a full-on adult. She gets a new apartment, a new haircut, and a new wardrobe, but when she logs onto the dating app that she has determined will find her new love, she sees none other than Jack, the guy whose room she snuck out of.