Birdie and Cole are the daughters of a black father and a white mother, intellectuals and activists in the Civil Rights Movement in 1970s Boston. The sisters are so close that they speak their own language, yet Birdie, with her light skin and straight hair, is often mistaken for white, while Cole is dark enough to fit in with the other kids at school. Despite their differences, Cole is Birdie's confidant, her protector, the mirror by which she understands herself. Then their parents' marriage collapses.

In the spring of 1981, the young Skinner siblings - fierce Renee, dreamy Caroline, golden boy Joe, and watchful Fiona - lose their father to a heart attack and their mother to a paralyzing depression, events that thrust them into a period they will later call “the Pause”. Caught between the predictable life they once led and an uncertain future that stretches before them, the siblings navigate the dangers and resentments of the Pause to emerge fiercely loyal and deeply connected. Two decades later, the Skinners find themselves again confronted with a family crisis....

In the turbulent summer of 1974, Kate Mularkey has accepted her place at the bottom of the eighth-grade social food chain. Then, to her amazement, the "coolest girl in the world" moves in across the street and wants to be her friend. Tully Hart seems to have it all - beauty, brains, ambition. On the surface they are as opposite as two people can be: Kate, doomed to be forever uncool, with a loving family who mortifies her at every turn.

In China there is a belief that people who are destined to be together are connected by an invisible red thread. After losing her infant daughter in a freak accident, Maya Lange opens The Red Thread, an adoption agency that specializes in placing baby girls from China with American families. Maya finds some comfort in her work, until a group of six couples share their personal stories of desire for a child.

Meghann Dontess is a woman haunted by heartbreak. Twenty-five years ago she was forced to make a terrible choice, one that cost her everything, including the love of her sister, Claire. Now, Meghann is a hotshot divorce attorney who doesn’t believe in intimacy - until she meets the one man who can change her mind.

Rachel Blum and Andy Landis are eight years old when they meet late one night in an ER waiting room. Born with a congenital heart defect, Rachel is a veteran of hospitals, and she's intrigued by the boy who shows up all alone with a broken arm. He tells her his name. She tells him a story. After Andy's taken back to the emergency room and Rachel's sent back to her bed, they think they'll never see each other again.

Allison Weiss is a typical working mother, trying to balance a business, aging parents, a demanding daughter, and a marriage. But when the website she develops takes off, she finds herself challenged to the point of being completely overwhelmed. Her husband’s becoming distant, her daughter’s acting spoiled, her father is dealing with early Alzheimer’s, and her mother’s barely dealing at all.

Aria is no stranger to tragedy. Fifteen years ago, a family outing took the lives of her father and baby sister, leaving remaining members of this fractured family struggling with their own guilt - real and imagined. At 25, Aria believes she can reinvent herself through her planned marriage with all its promise of a family of her own. Her infertility changes her life as swiftly and irrevocably as the urban landscape around her.

In this breathtaking and beautiful novel, the #1 New York Times best-selling author Anna Quindlen creates an unforgettable portrait of a mother, a father, a family, and the explosive, violent consequences of what seem like inconsequential actions.

Cannie Shapiro never wanted to be famous. The smart, sharp, plus-sized pop culture reporter was perfectly content writitng about other people's lives in the pages of the Philadlphia Examiner. But the day she opened up a national women's magazine to find out that her ex-boyfriend has been chronicling their ex-sex life is the day her life changes forever.

Set in the 1980s against the backdrop of a swiftly gentrifying Manhattan, The Lost Language of Cranes tells the story of 25-year-old Philip, who realizes he must come out to his parents after falling in love for the first time with a man. Philip's parents are facing their own crisis: pressure from developers and the loss of their longtime home.

Rebecca Rothstein Rabinowitz is a plump, sexy chef who has a wonderful husband, a restaurant that's received citywide acclaim, a beautiful baby girl and the mother-in-law from hell. Kelly Day's life looks picture-perfect. But behind the doors, she's struggling to balance work, motherhood, and marriage, while dealing with an unemployed husband who seems content to channel-surf for eight hours a day....

Franci and Lottie may be identical twins, but that’s where the similarities end. Franci has always been the stable one, while Lottie has bipolar disorder, constantly battling depression and mania. After years of taking care of her sister, Franci moves across the country to build a life for herself. Now, all the two share is distance. But when Lottie gets in an accident, Franci reluctantly steps back into her familiar role as protector. She returns to find her sister’s life in complete disarray and makes a shocking discovery: Lottie has an infant daughter she never told Franci about.

In 1962 a pregnant girl staggers into a health clinic, gives birth, and flees. A foster family takes the baby in, and an unlikely couple, their lives unspooling from the recent death of their infant, adopts her. Forty years and many secrets and lies later, Cheri Matzner is all grown up and falling apart. Ironic and fierce, she's a former cop turned disgruntled academic, a frustrated wife trying to get pregnant, an iconoclastic daughter bearing war wounds from her dysfunctional family.

After the sudden loss of Stella, her only child, Mary Baxter joins a knitting circle in Providence, Rhode Island. Seeking a way to fill the empty hours and lonely days, she little realizes that the circle will change her life.