In this episode, we discuss the genetic aspects of diabetes. Our guest, Dr. Beenish Masood, completed her medical education in Internal Medicine at Dow University of Health Sciences, Pakistan, and her Master's in Clinical Endocrinology at Queen Mary University of London. She has worked as a Research Clinical Fellow in Diabetes at Barts Health NHS Trust and as a Clinical Teaching Fellow in Diabetes and Endocrinology at The Royal Free Hospital in London, UK. Her research focuses on metabolic disorders, including diabetes. Reference: Masood B, Moorthy M. Causes of obesity: a review. Clin Med (Lond). 2023 Jul;23(4):284-291. doi: 10.7861/clinmed.2023-0168. PMID: 37524429; PMCID: PMC10541056.
Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we talk about the effects of alcohol on the brain, sleep, and circadian rhythm. This time, the conversation will be based on an animal model. Our guest, Dr. Anthony Lange, Ph.D., a Postdoctoral Research Scholar in Neuroscience & Pharmacology at the University of Iowa, will enlighten us about his research, which mainly focuses on the neural mechanisms underlying social behaviors. Enjoy!

Reference: Lange AP, Wolf FW. Alcohol sensitivity and tolerance encoding in sleep regulatory circadian neurons in Drosophila. Addict Biol. 2023 Aug;28(8):e13304. doi: 10.1111/adb.13304. PMID: 37500483; PMCID: PMC10911855.

Disclosure:

The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating role of epigenetics in sleep and sleep disorders. Our guest, Dr. Rene Cortese, a researcher in the Departments of Pediatrics and Obstetrics and Gynecology at the University of Missouri School of Medicine, brings his expertise in epigenetics and complex diseases to the discussion. Dr. Cortese’s research focuses on how complex diseases develop, progress, and are inherited, with a special emphasis on identifying potential treatments. His current work examines epigenetic mechanisms in genome regulation, especially those affecting children's and women's health. Hope you find this episode insightful! Reference: Cortese R. Epigenetics of Sleep Disorders: An Emerging Field in Diagnosis and Therapeutics. Diagnostics (Basel). 2021 May 10;11(5):851. doi: 10.3390/diagnostics11050851. PMID: 34068472; PMCID: PMC8150507.

Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we’re diving into the ketogenic diet in the context of bodybuilding and muscle preservation. Our guest, Dr. Antonio Paoli, Professor of Exercise and Sport Sciences at the Department of Biomedical Sciences, University of Padova, and Chair of Strength Training and Sport Nutrition at UCAM University in Murcia, Spain, will shed light on this compelling topic. Dr. Paoli's research focuses on the ketogenic diet, fasting, and the interaction between exercise and diet on skeletal muscle metabolism. He also explores the molecular foundations of exercise adaptation and the effects of various resistance training methods on health and body composition in both young and adult populations. Reference: Paoli A, Cenci L, Pompei P, Sahin N, Bianco A, Neri M, Caprio M, Moro T. Effects of Two Months of Very Low Carbohydrate Ketogenic Diet on Body Composition, Muscle Strength, Muscle Area, and Blood Parameters in Competitive Natural Body Builders. Nutrients. 2021 Jan 26;13(2):374. doi: 10.3390/nu13020374. PMID: 33530512; PMCID: PMC7911670.

Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore the fascinating role of fructose in our metabolism and how it might influence obesity through the “survival switch hypothesis.” Our guest, Dr. Richard Johnson from the Anschutz School of Medicine at the University of Colorado, joins us to discuss his insights on how fructose could be triggering significant changes in metabolism. Together, we dive into how these changes are implicated in obesity, insulin resistance, and other metabolic diseases. Join us for an enlightening conversation that could reshape the way we understand the impacts of fructose on health. Hope you enjoy the episode! Reference: Johnson RJ, Lanaspa MA, Sanchez-Lozada LG, Tolan D, Nakagawa T, Ishimoto T, Andres-Hernando A, Rodriguez-Iturbe B, Stenvinkel P. The fructose survival hypothesis for obesity. Philos Trans R Soc Lond B Biol Sci. 2023 Sep 11;378(1885):20220230. doi: 10.1098/rstb.2022.0230. Epub 2023 Jul 24. PMID: 37482773; PMCID: PMC10363705. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez

Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

Reference: Koob GF. Neurobiology of Opioid Addiction: Opponent Process, Hyperkatifeia, and Negative Reinforcement. Biol Psychiatry. 2020 Jan 1;87(1):44-53. doi: 10.1016/j.biopsych.2019.05.023. Epub 2019 Jun 12. PMID: 31400808. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we dive into a critical topic: how are we supporting each other globally to produce and publish research? Our guest, Emmanuel Ameh, Professor of Pediatric Surgery at the National Hospital in Abuja, Nigeria, shares valuable insights into the challenges faced in Africa when it comes to research and publication, challenges that are also experienced in Latin America. He discusses the initiatives and collaborations that have been developed to address these issues and improve the research landscape. This conversation is an eye-opener for anyone interested in the global research community. We hope you find it inspiring and insightful!

References:

-Krakauer KN, Wong LY, Tobias J, Majekodunmi O, Balumuka D, Bravo K, Ameh E, Finlayson S, Nwomeh B, Sifri Z, Charles A, Krishnaswami S; SUS Committee on Academic Global Surgery. Evaluating Global Surgery Partnerships From Low and Middle Income Country Perspectives. J Surg Res. 2024 Apr;296:681-688. doi: 10.1016/j.jss.2024.01.040. Epub 2024 Feb 15. PMID: 38364695.

-Peters AW, Roa L, Rwamasirabo E, Ameh E, Ulisubisya MM, Samad L, Makasa EM, Meara JG. National Surgical, Obstetric, and Anesthesia Plans Supporting the Vision of Universal Health Coverage. Glob Health Sci Pract. 2020 Mar 31;8(1):1-9. doi: 10.9745/GHSP-D-19-00314. PMID: 32234839; PMCID: PMC7108944.

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Disclosure:

The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.

In this episode, we explore one of the most exciting advancements in c4ncer care: liquid biopsy. How is this innovative technique transforming c4ncer detection and treatment? Dr. Christian Rolfo, MD, PhD, recently appointed as the Director of the Division of Medical Oncology at The Ohio State University Comprehensive Cancer Center, shares his expertise on this game-changing technology. Dr. Rolfo discusses how liquid biopsy is advancing precision medicine, detecting c4ncer biomarkers, and shaping the future of oncology. Tune in to learn how this breakthrough could be the next big leap in c4ncer treatment! Dr. Rolfo specializes in drug development, lung c4ncer, and thoracic malignancies, with a strong focus on biomarkers and resistance mechanisms. He has also been a Professor with tenure in the Division of Hematology and Medical Oncology, and a Professor at the Institute for Translational Epidemiology in Cancer, both at the Icahn School of Medicine, Mount Sinai Health System, New York. He has also served as the Associate Director of Clinical Research for the Center of Excellence for Thoracic Oncology at the Tisch Cancer Institute. Reference: Rolfo C, Malapelle U, Russo A. Expanding the Full Potential of Liquid Biopsies for Lung Cancer Patients. Cancer Res. 2022 Aug 16;82(16):2826-2828. doi: 10.1158/0008-5472.CAN-22-2109. PMID: 35971678. Visit the International Society of Liquid Biopsy website: https://islb.info/ Upcoming events: 6th Annual Congress of Liquid Biopsy: "Advancing and Accelerating Access of Liquid Biopsy” (ISLB 2024) in Denver, Colorado, USA. November 23-25, 2024. More info: https://2024.islb.info/ Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.