Drs Michelle Kittleson and Biykem Bozkurt provide game-changing updates and insights on treating heart failure with reduced ejection fraction.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982148). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://pubmed.ncbi.nlm.nih.gov/35363499/

Effects of Enalapril on Mortality in Severe Congestive Heart Failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS) https://pubmed.ncbi.nlm.nih.gov/2883575/

Prescribing SGLT2 Inhibitors in Patients With CKD: Expanding Indications and Practical Considerations https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263228/

Safety, Tolerability and Efficacy of Up-titration of Guideline-Directed Medical Therapies for Acute Heart Failure (STRONG-HF): A Multinational, Open-Label, Randomised Trial https://pubmed.ncbi.nlm.nih.gov/36356631/

Drs Michelle M. Kittleson and Gregg Fonarow share need-to-know nuances on initiating four HFrEF therapies in select patients.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982149). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

The Use of β-Blockers in Heart Failure With Reduced Ejection Fraction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8468030/

Vericiguat in Patients With Heart Failure and Reduced Ejection Fraction https://pubmed.ncbi.nlm.nih.gov/32222134/

Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103045/

Transcatheter Mitral-Valve Repair in Patients With Heart Failure https://pubmed.ncbi.nlm.nih.gov/30280640/

Drs Michelle Kittleson and Sana Al-Khatib explore the ins and outs of complex clinical decisions regarding device placement for patients who have heart failure with reduced ejection fraction.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982150). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death https://pubmed.ncbi.nlm.nih.gov/29097296/

Optimal CRT Implantation — Where and How to Place the Left-Ventricular Lead? https://pubmed.ncbi.nlm.nih.gov/34495452/

Current Device Therapies for Sudden Cardiac Death Prevention — The ICD, Subcutaneous ICD and Wearable ICD https://pubmed.ncbi.nlm.nih.gov/30389367/

Drs Michelle Kittleson and Jason N. Katz discuss how to navigate uncertain terrain using a few rules to balance choices, risks, and goals in managing device therapy for individuals with heart failure.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982158). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Medical Management of Advanced Heart Failure https://pubmed.ncbi.nlm.nih.gov/11829703/

William Osler https://pubmed.ncbi.nlm.nih.gov/3289809/

Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock: A Scientific Statement From the American Heart Association https://pubmed.ncbi.nlm.nih.gov/35862152/

Experience With Univentricular Support in Mortally Ill Cardiac Transplant Candidates https://pubmed.ncbi.nlm.nih.gov/2306148/

Drs Michelle Kittleson and Jennifer Ho discuss the vital clues to help diagnose and precisely treat heart failure with preserved ejection fraction.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982159). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://www.ahajournals.org/doi/10.1161/CIR.0000000000001063

Heart Failure With Preserved Ejection Fraction: A Kidney Disorder? https://www.ahajournals.org/doi/full/10.1161/circulationaha.116.022249

Optimal Pharmacologic Treatment of Heart Failure With Preserved and Mildly Reduced Ejection Fraction: A Meta-analysis https://pubmed.ncbi.nlm.nih.gov/36125813/

Drs Michelle Kittleson and James Januzzi discuss must-know intricacies of managing subgroups of patients with HFpEF.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982160). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2023 ACC Expert Consensus Decision Pathway on Management of Heart Failure With Preserved Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee https://www.jacc.org/doi/10.1016/j.jacc.2023.03.393

Heart Failure With Preserved Ejection Fraction: JACC Scientific Statement https://www.jacc.org/doi/10.1016/j.jacc.2023.01.049

Drs Michelle Kittleson and Mathew Maurer discuss the ins and outs of diagnosing and treating TTR amyloid cardiomyopathy.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982161). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Cardiac Amyloidosis: Evolving Diagnosis and Management: A Scientific Statement From the American Heart Association https://pubmed.ncbi.nlm.nih.gov/32476490/

Tafamidis Treatment for Patients With Transthyretin Amyloid Cardiomyopathy https://www.nejm.org/doi/full/10.1056/NEJMoa1805689

Two Decades of Cardiac Amyloidosis: A Danish Nationwide Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543084/

Drs Michelle Kittleson and Carolyn Ho have a delightful discussion about effective diagnosis and management for individuals with hypertrophic cardiomyopathy.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982162). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://www.ahajournals.org/doi/10.1161/CIR.0000000000000937 

Hypertrophic Cardiomyopathy https://www.ahajournals.org/doi/10.1161/circresaha.117.311059

Familial Hypertrophic Cardiomyopathy https://medlineplus.gov/genetics/condition/familial-hypertrophic-cardiomyopathy/