In the concluding segment of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about genetic leukodystrophies and the increasing recognition of these disorders in adult neurology, the importance of genetic testing, and the evolving treatment landscape.

Read the related articles in Neurology and CHS Perspectives.

Disclosures can be found at Neurology.org.

In the first part of this two-part series, Dr. Justin Abbatemarco talks with Dr. Jennifer L. Orthmann-Murphy about a practical approach to genetic leukodystrophies, focusing on the importance of genetic testing, identifying red flags in patients, and navigating the complexities of hereditary spastic paraplegia.

Read the related articles in Neurology and CHS Perspectives.

Disclosures can be found at Neurology.org.

The November 2024 replay features four episodes dedicated to brain health. It kicks off with an interview with Dr. Nicoline Schiess, who discusses the World Health Organization (WHO) Brain Health Unit. Next, Dr. Katrin Seeher delves into the global burden of neurological conditions and the WHO’s strategies to enhance care and awareness. The third segment features Dr. Natalia Rost who introduces and highlights the American Academy of Neurology’s (AAN) groundbreaking brain health initiative. The episode wraps up with Dr. Rost again, who returns to give an update and emphasize the urgency of addressing brain health amidst public health challenges.

Podcast Links:

WHO Brain Health Unit

Global Burden of Neurologic Conditions

Brain Health Initiative with Dr. Natalia Rost

Update on Brain Health with Dr. Natalia Rost

Article Links:

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

The Brain Health Imperative in the 21st Century—A Call to Action

AAN Brain Health Initiative

Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Drs. Marius Ringelstein and Ilya Ayzenberg about the effectiveness and safety of Eculizumab in routine clinical care.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

Dr. Tesha Monteith talks with Drs. Messoud Ashina and Andrea Cipriani about all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults.

Read the related article in the BMJ.

Disclosures can be found at Neurology.org.

Dr. Greg Cooper talks with Dr. Clifford R. Jack Jr about objective criteria for diagnosis and staging Alzheimer disease, highlighting recent advancements in biomarkers to bridge the gap between research and clinical practice.

Read the related article in Alzheimer's Association.

Disclosures can be found at Neurology.org.

Dr. Gordon Smith talks with Dr. Whitley Aamodt about end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences.

Read the related article in Neurology.

Disclosures can be found at Neurology.org.

Dr. Kait Nevel talks with Dr. Oumaima Aboubakr about the prevalence of epilepsy in primary CNS lymphoma, to identify factors associated with epilepsy, and to investigate the prognostic significance of seizures in PCNSL.

Read the related article in Neurology®.

Disclosures can be found at Neurology.org.