• 10 30 2023
    Oct 30 2023

    Hi, This Week in Nephrology, we will be discussing article published in  October  issues of the Nephrology journals.



     Journal of the American Society of Nephrology

    The Number and Size of Individual Kidney Medullary Pyramids is Associated with Clinical Characteristics, Kidney Biopsy Findings, and CKD Outcomes among Kidney Donors

    Clinical journal of the American Society of Nephrology

    Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy

    Performance Characteristics of Candidate Criteria for Hemodialysis Arteriovenous Fistula Maturation

    Nephrology dialysis transplantation  


    High rates of psychological distress, mental health diagnoses and suicide attempts in people with chronic kidney disease in Ireland

    Sex difference in cardiovascular risk in patients with chronic kidney disease: pooled analysis of four cohort studies

    Kidney international  

    A prospective controlled, randomized clinical trial of kidney transplant recipients developed personalized tacrolimus dosing using model-based Bayesian Prediction

    American journal of kidney diseases  


    Patient and Health Care Professional Perspectives on Addressing Obesity in ESKD

    Clinical kidney journal 



    High exposure to tacrolimus is associated with spontaneous remission of recurrent membranous nephropathy after kidney transplantation

    The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes 


    Evaluation of advanced imaging biomarkers at kidney failure in patients with ADPKD: a pilot study 

    Hypertension  ACC


    Prevalence of Chronic Kidney Disease Among US Adults With Hypertension, 1999 to 2018

    American journal of hypertension

    Efficacy of Allisartan Isoproxil in the Treatment of Mild-to-Moderate Essential Hypertension

    Transplantation

    Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus and Seroresponse to the Vaccinations in Adult Solid Organ Transplant Candidates

    American Journal of Transplantation


    Qualifying a novel clinical trial endpoint (iBOX) predictive of long-term kidney transplant outcomes

    Kidney international report article;




    Patient Preferences for the Management of Gastrointestinal Symptoms in Kidney Transplantation: a Discrete Choice Experiment

    Implications of Complete Proteinuria Remission at any Time in Focal Segmental Glomerulosclerosis: Sparsentan DUET Trial


    The Phenotypic Spectrum of COL4A3 Heterozygotes

    High-Throughput Splicing Assays Identify Known and Novel WT1 Exon 9 Variants in Nephrotic Syndrome

    JAMA Internal Medicine


    Disparities in Kidney Transplant Waitlisting Among Young Patients Without Medical Comorbidities




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    50 mins
  • 10 13 2023
    Oct 23 2023

    Hi, This Week in Nephrology, we will be discussing articles published in  October  issues of the Nephrology journals.

     Journal of the American Society of Nephrology

    Safety and Preliminary Efficacy of Mesenchymal Stromal Cell (ORBCEL-M) Therapy in Diabetic Kidney Disease: A Randomized Clinical Trial (NEPHSTROM)

    Clinical journal of the American Society of Nephrology

    Early Risk Stratification for Natural Disease Course in Fabry Patients Using Plasma Globotriaosylsphingosine Levels

    Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older Adults Receiving Dialysis

    JAMA

     

    Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection

    The ACORN Randomized Clinical Trial


      Nephrology dialysis transplantation  

    Comparable outcomes between a combination of peritoneal dialysis with once-weekly haemodialysis and thrice-weekly haemodialysis: a prospective cohort study


    The effect of micro-particle curcumin on chronic kidney disease progression: the MPAC-CKD randomized clinical trial

    Kidney international  

    Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

    American journal of kidney diseases  

    Kidney Transplantation From Hepatitis C Virus–Infected Donors to Uninfected Recipients: A Systematic Review for the KDIGO 2022 Hepatitis C Clinical Practice Guideline Update

    Acute Declines in Estimated GFR in Blood Pressure Target Trials and Risk of Adverse Outcomes

    Clinical kidney journal 

    Twenty-four-hour proteinuria levels are associated with adverse pregnancy outcomes among women with CKD 

    Critically ill patients with acute kidney injury: clinical determinants and post-mortem histology

    Hypertension  ACC

    Is Height2.7 Appropriate for Indexation of Left Ventricular Mass in Healthy Adolescents? The Importance of Sex Differences

    American journal of hypertension

    Observational and Genetic Evidence for Bidirectional Effects Between Red Blood Cell Traits and Diastolic Blood Pressure

    Transplantation

    Performance and Advancement of the Kidney Solid Organ Response Test

    American Journal of Transplantation


    Siplizumab combination therapy with belatacept or abatacept broadly inhibits human T cell alloreactivity in vitro

    Kidney international report article;


    Changes in Kidney Function Among Malaysian Adolescents and Its Determinants

    Considerable Variability Among Transplant Nephrologists in Judging Deceased Donor Kidney Offers

    Diagnosis of Kidney Diseases of Unknown Etiology Through Biopsy-Genetic Analysis

    Black Patients Equally Benefit From Renal Genetics Evaluation but Substantial Barriers in Access Exist



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    53 mins
  • 10 16 2023
    Oct 16 2023

    Hi, This Week in Nephrology, we will be discussing article published in  October  issues of the Nephrology journals.

    Journal of the American Society of Nephrology

    Renin–Angiotensin–Aldosterone System Blockade after AKI with or without Recovery among US Veterans with Diabetic Kidney Disease

    Clinical journal of the American Society of Nephrology

    Kaliuresis and Intracellular Uptake of Potassium with Potassium Citrate and Potassium Chloride Supplements: A Randomized Controlled Trial

    Efficacy and Safety of Upacicalcet in Hemodialysis Patients with Secondary Hyperparathyroidism: A Randomized Placebo-Controlled Trial

    Perspectives of Nephrologists on Gender Disparities in Access to Kidney Transplantation

    Nephrology dialysis transplantation  

    Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial 

    Peritoneal transformation shortly after kidney transplantation in p

    Kidney international  

    A cohort study found a high risk of end-stage kidney disease associated with acromegaly

    American journal of kidney diseases  

    The Impact of the COVID-19 Pandemic on Patients With CKD: Systematic Review of Qualitative Studies


    Blood Pressure, Incident Cognitive Impairment, and Severity of CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study

    Clinical kidney journal 

    Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients

    The impact of in-centre haemodialysis treatment on the everyday life of older adults with end-stage kidney disease: a qualitative study

    Hypertension  ACC

    PREPARE: A Stepped-Wedge Cluster-Randomized Trial to Evaluate Whether Risk Stratification Can Reduce Preterm Deliveries Among Patients With Suspected or Confirmed Preterm Preeclampsia

    American journal of hypertension


    Specialized Pro-resolving Mediator Improves Vascular Relaxation via Formyl Peptide Receptor-2

    Transplantation

    Immunized Patients Face Reduced Access to Transplantation in the Eurotransplant Kidney Allocation System

    American Journal of Transplantation

    Validation of a prediction system for risk of kidney allograft failure in pediatric kidney transplant recipients: An international observational study

    Kidney international report article;


    Epidemiology and Outcomes of Children with Kidney Failure Receiving Kidney Replacement Therapy in Australia and New Zealand

    Feasibility Analysis of Ultrasound-Guided Placement of Tunneled Hemodialysis Catheters

     Rate of Kidney Function Decline is Associated With Kidney and Heart Failure in Individuals With Type 1 Diabetes

    Kidney Outcomes Following Utilization of Molecular Adsorbent Recirculating System









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    49 mins
  • 10 9 2023
    Oct 9 2023

    Hi, This Week in Nephrology, we will be discussing article published in October issues of the Nephrology journals.

    Journal of the American Society of Nephrology

    Research and Nonresearch Industry Payments to Nephrologists in the United States between 2014 and 2021

    Nephrology dialysis transplantation  


    Treatment and long-term outcome in primary nephrogenic diabetes insipidus


    Long-term outcomes of COVID-19 survivors with hospital AKI: association with time to recovery from AKI

    Kidney international  

    American journal of kidney diseases  


    Utility of the Kidney Failure Risk Equation and Estimated GFR for Estimating Time to Kidney Failure in Advanced CKD


    Multifaceted Quality Improvement Interventions to Prevent Hemodialysis Catheter–Related Bloodstream Infections: A Systematic Review



    Clinical kidney journal 


    Recurrent cardiovascular events in patients with type 2 diabetes and haemodialysis: analysis from the 4D Study

    pted

    Hypertension ACC

    Unilaterally Selective Adrenal Vein Sampling for Identification of Surgically Curable Primary Aldosteronism

    American journal of hypertension


    Sex Differences in Atrial Fibrillation and Associated Complications in Hypertensive Patients with Left Ventricular Hypertrophy: The LIFE Study

    Transplantation


    Evaluation of Immunocompetence and Biomarkers of Tolerance in Chimeric and Immunosuppression-free Kidney Allograft Recipients

    American Journal of Transplantation


    Survival after kidney transplantation compared with ongoing dialysis for people over 70 years of age: A matched-pair analysis

    Kidney international report :

    Effect of a Multifaceted Intervention on the Incidence of Hemodialysis Catheter Dysfunction in a National Stepped-Wedge Cluster Randomized Trial

    Residual Kidney Function and Cause-Specific Mortality Among Incident Hemodialysis Patients


    Determinants of Kidney Failure in Primary Hyperoxaluria Type 1: Findings of the European Hyperoxaluria Consortium


    Changing Phenotypes and Clinical Outcomes Over Time in Microscopic Polyangiitis

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    41 mins
  • 10 1 2023
    Oct 2 2023

    Hi, This Week in Nephrology, we will be discussing article published in September issues of the Nephrology journals.

    Journal of the American Society of Nephrology


    Dysfunctional Coupling of Cerebral Blood Flow and Susceptibility Value in the Bilateral Hippocampus is Associated with Cognitive Decline in Nondialysis Patients with CKD


    Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial


    Clinical journal of the American Society of Nephrology

    Long-Term, Real-World Kidney Outcomes with SGLT2i versus DPP4i in Type 2 Diabetes without Cardiovascular or Kidney Disease

    Immunosuppression versus Supportive Care on Kidney Outcomes in IgA Nephropathy in the Real-World Setting

    Nephrology dialysis transplantation  

    Malignancy risk in kidney transplant recipients exposed to immunosuppression pre-transplant for the treatment of glomerulonephritis Acute kidney injury in bortezomib-treated patients with multiple myeloma


    Kidney international  


    A nationwide cohort study comparing the effectiveness of diuretics and calcium channel blockers on top of renin-angiotensin system inhibitors on chronic kidney disease progression and mortality


    American journal of kidney diseases  


    Integrated Analysis of Blood and Urine Biomarkers to Identify Acute Kidney Injury Subphenotypes and Associations With Long-term Outcomes

     

    Evaluation of Plasma Biomarkers to Predict Major Adverse Kidney Events in Hospitalized Patients With COVID-19

     Clinical kidney journal 


    Kidney injury molecule 1 (KIM-1): a potential biomarker of acute kidney injury and tubulointerstitial injury in patients with ANCA-glomerulonephritis

    Clinical and immunological characteristics of patients with combined anti-glomerular basement membrane disease and IgA nephropathy

    Hypertension  ACC


    Association Between Maternal Glucose Levels in Gestational Diabetes Screening and Subsequent Hypertension

     American journal of hypertension


    SNAP Participation and Medication Adherence Among Older Black Medicaid-Insured Individuals Living With Hypertension


    Transplantation

    Cost-effectiveness of Kidney Transplantation From Donors at Increased Risk of Blood-borne Virus Infection Transmission

    Outcomes With Belatacept Exposure During Pregnancy in Kidney Transplant Recipients: A Case Series


    American Journal of Transplantation


    Diagnosis and treatment of allograft rejection in islet transplantation

    Kidney international report  


    Effect of Belimumab on Preventing de novo Renal Lupus Flares

     

    The Association Between Metabolic Syndrome, Hyperfiltration, and Long-Term GFR Decline in the General Population

     Hyperfiltration can prevent loss of GFR in persons with MetS.




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    51 mins
  • 9 25 2023
    Sep 25 2023

    Hi, This Week in Nephrology, we will be discussing article published in September issues of the Nephrology journals.

    Journal of the American Society of Nephrology


    Genome-Wide Association Study of CKD Progression


    Effects of a More Selective Arteriovenous Fistula Strategy on Vascular Access Outcomes


    Clinical journal of the American Society of Nephrology


    Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function


    Discrepancies between Cystatin C–Based and Creatinine-Based eGFR


    Nephrology dialysis transplantation  


    Long-term peridialytic blood pressure changes are related to mortality

    Early acute kidney injury is associated with in-hospital adverse outcomes in critically ill burn patients: an observational study

    Kidney international  


    Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial

    American journal of kidney diseases  


    Serum Potassium and Risk of Death or Kidney Replacement Therapy in Older People With CKD Stages 4-5: Eight-Year Follow-up

    Metformin Use and Long-term Clinical Outcomes in Kidney Transplant Recipients

    Clinical kidney journal 


    Associations between eGFR and albuminuria with right ventricular measures: the MESA-Right Ventricle study 



    Standard versus no post-filter ionized calcium monitoring in regional citrate anticoagulation for continuous renal replacement therapy (NPC trial)

    Hypertension  ACC



    Intensive Blood Pressure Lowering Improves Left Ventricular Hypertrophy in Older Patients with Hypertension: The STEP Trial

    American journal of hypertension


    Intensive Blood Pressure Control and Cardiovascular Outcomes in Elderly Patients: A Secondary Analysis of SPRINT Study Based on a 60-Year Age Cutoff

    Transplantation


    Robotic Versus Laparoscopic Donor Nephrectomy: A Retrospective Bicentric Comparison of Learning Curves and Surgical Outcomes From 2 High-volume European Centers


    Bariatric Surgery in Severely Obese Kidney Donors Before Kidney Transplantation: A Retrospective Study

    American Journal of Transplantation

    The role of interleukin-21 in COVID-19 vaccine–induced B cell–mediated immune responses in patients with kidney disease and kidney transplant recipients

    Kidney international report

    Randomized Controlled Clinical Trial of the Effect of Treatment with Vitamin K2 on Vascular Calcification in Hemodialysis Patients (Trevasc-HDK)

    ;Infectious Risk and Variability of Hemoglobin Level in Patients Undergoing Hemodialysis




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    51 mins
  • 9 19 2023
    Sep 19 2023

    Articles:

    Journal of the American Society of Nephrology: Efficacy and Safety of Eculizumab in Pediatric Patients Affected by Shiga Toxin–Related Hemolytic and Uremic Syndrome: A Randomized, Placebo-Controlled Trial

    Clinical journal of the American Society of Nephrology: Ferric Carboxymaltose in Iron-Deficient Patients with Hospitalized Heart Failure and Reduced Kidney Function

    Nephrology dialysis transplantation: Malignancy risk in kidney transplant recipients exposed to immunosuppression pre-transplant for the treatment of glomerulonephritis

    Kidney International:Bio-impedance spectroscopy added to a fluid management protocol does not improve preservation of residual kidney function in incident hemodialysis patients in a randomized controlled trial .

    American journal of kidney diseases  Serum Potassium and Risk of Death or Kidney Replacement Therapy in Older People With CKD Stages 4-5: Eight-Year Follow-up

    Clinical kidney journal Women's representation in clinical trials of patients with chronic kidney disease

    Hypertension  ACC: Intensive Blood Pressure Lowering Improves Left Ventricular Hypertrophy in Older Patients with Hypertension: The STEP Trial

    American journal of hypertension effects of allisartan isoproxil monotherapy on blood pressure (BP)

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    16 mins