Matthew Bartholomew, unorthodox but effective physician to Michaelhouse college in medieval Cambridge, is as worried as anyone about the pestilence that is ravaging Europe and seems to be approaching England. But he is distracted by the sudden and inexplicable death of the Master of Michaelhouse - a death the University authorities do not want investigated.

Salisbury, 1226. A young pregnant woman is found tangled in reeds in the river Avon, her identity a mystery. Grieving widow Ela Longespée is determined to succeed her husband as sheriff of Salisbury, and quickly takes charge of the investigation. She soon finds herself in the thick of a neighborhood scandal and a struggle to maintain her authority. With multiple suspects, can she identify the true killer?

Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, feeling no certain calling despite a lively faith, he turns to the profession of surgeon, training in Paris and then hanging out his sign in Oxford. A local lord asks him to track the killer of a young woman whose bones have been found in the castle cesspit. She is identified as the impetuous missing daughter of a local blacksmith, and her young man, whom she had provoked very publicly, is in due course arrested and sentenced at the Oxford assizes.

In the sapping summer heat of 1665, there is little celebration in London of the naval victory at the Battle of Lowestoft. The King, his retinue and anyone with sufficient means has fled the plague-ridden city, its half-deserted streets echoing the sound of bells tolling the mounting number of deaths. Those who remain clutch doubtful potions to ward off the relentless disease and dart nervously past shuttered buildings, watchful for the thieves who risk their lives to plunder what has been left behind.

The plague raging through London in 1665 has emptied the city. The only people left are those too poor to flee or those who selflessly struggle to control the contagion and safeguard the capital's future. Amongst them, though, are those prepared to risk their health for money - those who sell dubious 'cures' and hawk food at wildly inflated prices. Also amongst them are those who hold in their hands the future of the city's most iconic building - St Paul's Cathedral.

December 1927. Mystery-writer Marius Quin has one previous bestseller, endless looming mortgage payments, and no idea how to write his next book. When his childhood friend Lady Isabella Montague invites him to an intimate New Year’s Eve party hosted by a narcissistic actor, Marius seizes upon the distraction. With his perpetually glum Basset hound along for the ride, he navigates the snowy lanes to the opulent estate of Everham Hall. As the celebrations begin, fireworks light up the sky, champagne corks pop, and then the host is murdered…

At the end of her first unsuccessful season out in society, Lady Georgiana has all but given up on attracting a suitable man - until she receives an invitation to a masked Halloween ball at Broxley Manor. Georgie is uncertain why she was invited, until she learns that the royal family intends to marry her off to a foreign prince, one reputed to be mad.

The much-feared and hated Eudo - the Lord Bishop of Winchester's clerk - is bludgeoned to death in Pershore Abbey and laid before the altar in the attitude of a penitent. Everyone who had contact with him had reason to dislike him, but who had reason to kill him? The Sheriff of Worcestershire's thief taker, wily Serjeant Catchpoll, and his new and unwanted superior, Undersheriff Hugh Bradecote, have to find the answer. And as the walls of the abbey close in on the suspects, the killer strikes again....

Ralph Delchard, a soldier who fought at the Battle of Hastings, and Gervase Bret, a talented lawyer, have been commissioned by William the Conqueror to look into irregularities brought to light during the compilation of the Domesday Book. A man’s body is found mutilated in Savernake Forest and the residents of Bedwyn sleep uneasy at night, fearing a monster stalking the town. When Ralph Delchard and Gervase Bret arrive, they discover that the locals are harbouring dark secrets and that the real killer may be a little closer to home....

Oxford, Spring 1353. When young bookseller Nicholas Elyot discovers the body of student William Farringdon floating in the river Cherwell, it looks like a drowning. Soon, however, Nicholas finds evidence of murder. Who could have wanted to kill this promising student? As Nicholas and his scholar friend Jordain try to unravel what lies behind William's death, they learn that he was innocently caught up in a criminal plot.

When the body of a young man is found stuffed into the tomb of a medieval knight, Parish Constable Daniel Haze is tasked with investigating his first solo murder case. Suspicion instantly falls on the only stranger to arrive in the village of Birch Hill just before the crime took place, but the American captain proves to be an unexpected asset. A former soldier and a skilled surgeon, Jason Redmond is not only willing to assist Haze with the investigation but will risk his own safety to apprehend the killer.

For Emily, accepting the proposal of Philip, the viscount Ashton, was an easy way to escape her overbearing mother, who was set on a grand society match. So when Emily's dashing husband died on safari soon after their wedding, she felt little grief. After all, she barely knew him. Now, nearly two years later, she discovers that Philip was a far different man from the one she had married so cavalierly.

In the fair autumn of Our Lord's grace 1431, the nuns of England's St. Frideswide's prepare for the simply ceremonies in which the saintly novice Thomasine will take her holy vows. But their quiet lives of beauty and prayer are thrown into chaos by the merciless arrival of Lady Ermentrude Fenner and her retinue of lusty men, sinful women, and baying hounds. The hard-drinking dowager even keeps a pet monkey for her amusement. She demands wine, a feast.... And her niece, the angelic Thomasine.

The Earl of Wrexford possesses a brilliant scientific mind, but boredom and pride lead him to reckless behavior. He does not suffer fools gladly. So when pompous, pious Reverend Josiah Holworthy publicly condemns him for debauchery, Wrexford unsheathes his rapier-sharp wit and strikes back. As their war of words escalates, London's most popular satirical cartoonist, A. J. Quill, skewers them both.

London, September 1666. The Great Fire rages through the city, consuming everything in its path. Even the impregnable cathedral of St. Paul's is engulfed in flames and reduced to ruins. Among the crowds watching its destruction is James Marwood, son of a disgraced printer and reluctant government informer. In the aftermath of the fire, a semi-mummified body is discovered in the ashes of St. Paul's, in a tomb that should have been empty. The man's body has been mutilated, and his thumbs have been tied behind his back.