From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Conjectures and Refutations is one of Karl Popper’s most wide-ranging and popular works, notable not only for its acute insights into the way scientific knowledge grows, but also for applying those insights to politics and to history. It provides one of the clearest and most accessible statements of the fundamental idea that guided his work: not only our knowledge but our aims and our standards grow through an unending process of trial and error.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.

Darwin's theory of evolution is accepted by most educated Americans as simple fact. This easy acceptance, however, hides from us the many ways in which evolution - as an idea - shapes our thinking about a great many things. What if this idea is wrong? What if "evolution" is just a word that covers up scientific ignorance of how the wonders of the living world could have been created? Berkeley law professor Phillip Johnson looks at the evidence for Darwinistic evolution the way a lawyer would - with a cold dispassionate eye for logic and proof.

Science and Christianity are often presented as opposites, when in fact the order of the universe and the complexity of life powerfully testify to intelligent design. With this comprehensive resource that includes the latest research, you'll witness how the findings of scientists provide compelling reasons to acknowledge the mind and presence of a creator.

Named one of the top books of 2009 by the Times Literary Supplement (London), this controversial and compelling audiobook from Dr. Stephen C. Meyer presents a convincing new case for intelligent design (ID) based on revolutionary discoveries in science and DNA. Along the way Meyer argues that Charles Darwin's theory of evolution as expounded in The Origin of Species did not, in fact, refute ID.

When Charles Darwin finished The Origin of Species, he thought that he had explained every clue but one. Though his theory could explain many facts, Darwin knew that there was a significant event in the history of life that his theory did not explain. During this event, the "Cambrian explosion", many animals suddenly appeared in the fossil record without apparent ancestors in earlier layers of rock. In Darwin's Doubt, Stephen C. Meyer tells the story of the mystery surrounding this explosion of animal life.

Naming Darwin's Black Box to the National Review's list of the 100 most important nonfiction works of the 20th century, George Gilder wrote that it "overthrows Darwin at the end of the 20th century in the same way that quantum theory overthrew Newton at the beginning". Discussing the book in the New Yorker in May 2005, H. Allen Orr said of Behe, "He is the most prominent of the small circle of scientists working on intelligent design, and his arguments are by far the best known."

More than 30 years after his landmark book Evolution: A Theory in Crisis (1985), biologist Michael Denton revisits his thesis about the inability of Darwinian evolution to explain the history of life. From the origin of life to the origin of human language, the great divisions in the natural order are still as profound as ever, and still unsupported by the series of adaptive transitional forms predicted by Darwin. Denton makes a provocative new argument about the pervasiveness of nonadaptive order throughout biology, order that cannot be explained by the Darwinian mechanism.

Who are we, and how did we get here? These are two of the most fundamental and far-reaching questions facing scientists and cosmologists alike and have rested at the center of human intellectual endeavor since its beginning. They are questions that stretch across numerous disciplines. Philosophy, theology, evolutionary biology, and mathematics are just some of the fields looking to explain the emergence of human life.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator.

In 2010, scientists led by J. Craig Venter became the first to successfully create "synthetic life" - putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

In Consilience (a word that originally meant "jumping together"), Edward O. Wilson renews the Enlightenment's search for a unified theory of knowledge in disciplines that range from physics to biology, the social sciences and the humanities. Using the natural sciences as his model, Wilson forges dramatic links between fields. Presenting the latest findings in prose of wonderful clarity and oratorical eloquence, and synthesizing it into a dazzling whole, Consilience is science in the path-clearing traditions of Newton, Einstein, and Richard Feynman.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.

Edward J. Larson is a Pulitzer Prize-winning author and eminent science historian. This marvelously readable, yet sumptuously erudite work traces the development of the scientific theory of evolution. From Darwin's essential trip to the Galápagos, to the most contemporary studies in sociobiology, this work takes listeners both into the field and laboratories of the world's greatest evolutionary scientists, and shows how the theory of evolution has itself evolved.

Columnist and publisher Michael Shermer, once an evangelical Christian and a creationist, argues that Intelligent Design proponents invoke a combination of ad science, political antipathy, and flawed theology in their new brand of creationism. He refutes their pseudoscientific arguments and then demonstrates why conservatives and people of faith can and should embrace evolution. Why Darwin Matters is an incisive examination of what is at stake in the debate over evolution.

Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built - and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.

Scientific developments radically alter our understanding of the world. Whether it's technology, climate change, health research, or the latest revelations of neuroscience, physics, or psychology, science has, as Edge editor John Brockman says, "become a big story, if not the big story". In that spirit this new addition to Edge.org's fascinating series asks a powerful and provocative question: What do you consider the most interesting and important recent scientific news?

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Far too often, public discussion of science is carried out by journalists, voters, and politicians who have received their science secondhand. The Story of Western Science shows us the joy and importance of reading groundbreaking science writing for ourselves and guides us back to the masterpieces that have changed the way we think about our world, our cosmos, and ourselves.

Praised for his erudite writing, renowned scientist Frank Gonzalez-Crussi penned this concise history of medicine, beginning with the most primitive health-care practices and ending with the technology of modern medicine that we enjoy today. As with all Modern Library Chronicles, A Short History of Medicine is a wonderful primer for anyone interested in the subject.

Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.

Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.

This revised edition of Human Nature begins a new phase in the most important intellectual controversy of this generation: Is human behavior controlled by the species' biological heritage? Does this heritage limit human destiny?

With characteristic pungency and simplicity of style, the author of Sociobiology challenges old prejudices and current misconceptions about the nature-nurture debate.

Mystics and sages have long maintained that there exists an interconnecting cosmic field at the roots of reality that conserves and conveys information, a field known as the Akashic record. Recent discoveries in vacuum physics show that this Akashic field is real and has its equivalent in science's zero-point field that underlies space itself. This field consists of a subtle sea of fluctuating energies from which all things arise: atoms and galaxies, stars and planets, living beings, and even consciousness.

In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.

Physics informs our understanding of how the world works - but more than that, key breakthroughs in physics have transformed everyday life. We journey back to 10 separate days in history to understand how particular breakthroughs were achieved, meet the individuals responsible and see how each breakthrough has influenced our lives.

Eclipses have stunned, frightened, emboldened, and mesmerized people for thousands of years. They were recorded on ancient turtle shells discovered in the Wastes of Yin in China, on clay tablets from Mesopotamia and on the Mayan "Dresden Codex". They are mentioned in Homer's Iliad and Odyssey and at least eight times in the Bible. Columbus used them to trick people, while Renaissance painter Taddeo Gaddi was blinded by one. Sorcery was banished within the Catholic Church after astrologers used an eclipse to predict a pope's death.

Although we usually think of technology as something unique to modern times, our ancestors began to create the first technologies millions of years ago in the form of prehistoric tools and weapons. Over time, eight key technologies gradually freed us from the limitations of our animal origins.

The 13th person to walk on the moon could soon be part of a crew establishing a base on the lip of a crater at the lunar south pole. The discovery of ice in the eternal shadows of the polar regions transforms our ability to live on the moon. From bases on the moon we can make the long, lonely and dangerous voyage to Mars, where there is also ice. The obstacles are many, not least the fragilities of the human body. And what type of world would the first Mars explorers find?

In these brilliant essays, Lightman explores the emotional life of science, the power of imagination, the creative moment, and the alternate ways in which scientists and humanists think about the world. Along the way, he provides in-depth portraits of some of the great geniuses of our time, including Albert Einstein, Richard Feynman, Edward Teller, and astronomer Vera Rubin. Thoughtful, beautifully written, and wonderfully original, A Sense of the Mysterious confirms Alan Lightman's unique position at the crossroads of science and art.

After the Soviet Union proved to the United States that it possessed an operational intercontinental ballistic missile with the launch of Sputnik in October 1957, the world watched anxiously as the two superpowers engaged in a game of nuclear one-upmanship. Amid this rising tension, eccentric physicist Nicholas Christofilos brought forth an outlandish, albeit ingenious, idea to defend the US from a Soviet attack: detonating nuclear warheads in space to create an artificial radiation belt that would fry incoming ICBMs. Known as Operation Argus, this plan is the most secret and riskiest experiment in history, and classified details of these nuclear tests have been long obscured.

Over the last 50 years, humanity has developed an extraordinary shared utility: the global positioning system. Omnipresent, free, and available to all, GPS powers everything from your phone to the Internet to the Mars Rover. Greg Milner tells the sweeping story of GPS, from its conceptual origins as a bomb guidance system to its present ubiquity.

Learn how to separate internet fact from fiction. We live in the information age, giving us access to every datum ever collected and every opinion its originator thought fit to share. But with this newfound access to information comes a new challenge. Namely, how can you tell what information is true and what is false? In Is This Wi-Fi Organic? Dave Farina, author and science expert from the YouTube channel Professor Dave Explains, is here to help you fight confirmation bias and logical fallacies.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

Ever since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other. Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man....