Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

Are art and science separated by an unbridgeable divide? Can they find common ground? In this book, neuroscientist Eric R. Kandel, whose remarkable scientific career and deep interest in art give him a unique perspective, demonstrates how science can inform the way we experience a work of art and seek to understand its meaning. Kandel illustrates how reductionism - the distillation of larger scientific or aesthetic concepts into smaller, more tractable components - has been used by scientists and artists alike to pursue their respective truths.

A breakout best seller in Italy, now available for American listeners for the first time, Genesis: The Story of How Everything Began is a short, humanistic tour of the origins of the universe, earth, and life - drawing on the latest discoveries in physics to explain the seven most significant moments in the creation of the cosmos.

Have you ever wondered why you have a brain? Let renowned neuroscientist Lisa Feldman Barrett demystify that big gray blob between your ears. In seven short essays (plus a bite-sized story about how brains evolved), this slim, entertaining, and accessible collection reveals mind-expanding lessons from the front lines of neuroscience research. You'll learn where brains came from, how they're structured (and why it matters), and how yours works in tandem with other brains to create everything you experience.

While serving with the Peace Corps in Swaziland, Thomas Cowan encountered the work of Rudolf Steiner and Weston A. Price - two men whose ideas would fascinate and challenge him for decades to come. Both drawn to the art of healing and repelled by the way medicine was - and continues to be - practiced in the United States, Cowan returned from Swaziland, went to medical school, and established a practice.

"Ants are the most warlike of all animals, with colony pitted against colony.... Their clashes dwarf Waterloo and Gettysburg", writes Edward O. Wilson in his most finely observed work in decades. In a myrmecological tour to such far-flung destinations as Mozambique and New Guinea, the Gulf of Mexico's Dauphin Island and even his parents' overgrown yard back in Alabama, Wilson thrillingly evokes his nine-decade-long scientific obsession with more than 15,000 ant species.

Understanding someone who belongs to another species can be transformative. No one knows this better than author, naturalist, and adventurer Sy Montgomery. To research her books, Sy has traveled the world and encountered some of the planet's rarest and most beautiful animals. From tarantulas to tigers, Sy's life continually intersects with and is informed by the creatures she meets. This restorative memoir reflects on the personalities and quirks of 13 animals - Sy's friends - and the truths revealed by their grace.

A little over a decade ago, Baron Baptiste published his seminal book, Journey into Power. The first of its kind, it introduced the world to Baptiste Yoga, his signature method that marries a lifetime of studying with some of the world's most renowned yoga masters with his uniquely powerful approach to inner and outer transformation. Since then, yoga has steadily moved into the mainstream in our culture, and Baron's unique contribution has played a key role.

Cooperation is the means by which life arose in the first place. It’s how we progressed through scale and complexity, from free-floating strands of genetic material, to nation states. But given what we know about the mechanisms of evolution, cooperation is also something of a puzzle. How does cooperation begin, when on a Darwinian level, all that the genes in your body care about is being passed on to the next generation? A biologist by training, Raihani looks at where and how collaborative behavior emerges throughout the animal kingdom, and what problems it solves.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

Bringing together the best and most interesting science stories appearing in Quanta Magazine over the past five years, Alice and Bob Meet the Wall of Fire reports on some of the greatest scientific minds as they test the limits of human knowledge. It communicates science by taking it seriously, wrestling with difficult concepts, and clearly explaining them in a way that speaks to our innate curiosity about our world and ourselves.

For decades, biology has been dominated by the study of genetic information. Information is important, but it is only part of what makes us alive. Our inheritance also includes our living metabolic network, a flame passed from generation to generation, right back to the origin of life. In Transformer, biochemist Nick Lane reveals a scientific renaissance that is hiding in plain sight-how the same simple chemistry gives rise to life and causes our demise.

When you listen to music, do you prefer lyrics or melody? Intricate harmonies or driving rhythm? The “real” sounds of acoustic instruments or those of computerized synthesizers? Drawing from her successful career as a music producer (engineering hits like Prince’s “Purple Rain”), professor of cognitive neuroscience Susan Rogers reveals why your favorite songs move you. She explains that we each possess a unique “listener profile” based on our brain’s reaction to seven key dimensions of any record: authenticity, realism, novelty, melody, lyrics, rhythm, and timbre.

Though created by humans, our technologies, markets, and institutions often contain an antihuman agenda. Douglas Rushkoff, digital theorist and host of the NPR-One podcast Team Human, reveals the dynamics of this antihuman machinery and invites us to remake these aspects of society in ways that foster our humanity. In 100 aphoristic statements, his manifesto exposes how forces for human connection have turned into ones of isolation and repression.

In Your Brain Is a Time Machine, brain researcher and best-selling author Dean Buonomano draws on evolutionary biology, physics, and philosophy to present his influential theory of how we tell and perceive time. The human brain, he argues, is a complex system that not only tells time but creates it; it constructs our sense of chronological flow and enables "mental time travel" - simulations of future and past events.

The Earth teems with life: in its oceans, forests, skies, and cities. Yet there's a black hole at the heart of biology. We do not know why complex life is the way it is, or, for that matter, how life first began. In The Vital Question, award-winning author and biochemist Nick Lane radically reframes evolutionary history, putting forward a solution to conundrums that have puzzled generations of scientists.

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.

In The Equations of Life, biologist Charles S. Cockell makes the forceful argument that the laws of physics narrowly constrain how life can evolve, making evolution's outcomes predictable. If we were to find something very much like a lady bug eating something very much like an aphid on a distant planet, we shouldn't be surprised. The forms of life are guided by a limited set of rules, and, as a result, there is a narrow set of solutions to the challenges of existence.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: Nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?

Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?

Blending biology, chemistry, and physics basics with accessible - and witty-prose, The Science of Rick and Morty equips you with the scientific foundation to thoroughly understand Rick's experiments from the show, such as how we can use dark matter and energy, just what is intelligence hacking, and whether or not you can really control a cockroach's nervous system with your tongue. Perfect for longtime and new fans of the show, this is the ultimate segue into discovering more about our complicated and fascinating universe.

Paul Falkowski looks "under the hood" of microbes to find the engines of life, the actual working parts that do the biochemical heavy lifting for every living organism on Earth. With insight and humor, he explains how these miniature engines are built - and how they have been appropriated by and assembled like Lego sets within every creature that walks, swims, or flies. Falkowski shows how evolution works to maintain this core machinery of life, and how we and other animals are veritable conglomerations of microbes.

The Blind Watchmaker, knowledgably narrated by author Richard Dawkins, is as prescient and timely a book as ever. The watchmaker belongs to the 18th-century theologian William Paley, who argued that just as a watch is too complicated and functional to have sprung into existence by accident, so too must all living things, with their far greater complexity, be purposefully designed. Charles Darwin's brilliant discovery challenged the creationist arguments; but only Richard Dawkins could have written this elegant riposte.

Until the End of Time is Brian Greene's breathtaking new exploration of the cosmos and our quest to find meaning in the face of this vast expanse. Greene takes us on a journey from the big bang to the end of time, exploring how lasting structures formed, how life and mind emerged, and how we grapple with our existence through narrative, myth, religion, creative expression, science, the quest for truth, and a deep longing for the eternal.

Mystics and sages have long maintained that there exists an interconnecting cosmic field at the roots of reality that conserves and conveys information, a field known as the Akashic record. Recent discoveries in vacuum physics show that this Akashic field is real and has its equivalent in science's zero-point field that underlies space itself. This field consists of a subtle sea of fluctuating energies from which all things arise: atoms and galaxies, stars and planets, living beings, and even consciousness.

Infinite Powers recounts how calculus tantalized and thrilled its inventors, starting with its first glimmers in ancient Greece and bringing us right up to the discovery of gravitational waves. Strogatz reveals how this form of math rose to the challenges of each age: how to determine the area of a circle with only sand and a stick; how to explain why Mars goes "backwards" sometimes; how to turn the tide in the fight against AIDS.

Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on the Higgs boson and extra dimensions but now also on our deepest personal questions. Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void?

Throughout his distinguished and unconventional career, engineer-turned-molecular-biologist Douglas Axe has been asking the questions that much of the scientific community would rather silence. Now, he presents his conclusions in this brave and pioneering book. Axe argues that the key to understanding our origin is the "design intuition" - the innate belief held by all humans that tasks we would need knowledge to accomplish can be accomplished only by someone who has that knowledge.

Not just another science audiobook and not just another Discworld novella, The Science of Discworld is a creative, mind-bending mash-up of fiction and fact, that offers a wizard’s-eye view of our world that will forever change how you look at the universe.

Critical Path is Fuller's master work - the summing up of a lifetime's thought and concern - as urgent and relevant as it was upon its first publication in 1981. Critical Path details how humanity found itself in its current situation - at the limits of the planet's natural resources and facing political, economic, environmental, and ethical crises.

Rules of the quantum world seem to say that a cat can be both alive and dead at the same time and a particle can be in two places at once. And that particle is also a wave; everything in the quantum world can described in terms of waves - or entirely in terms of particles. These interpretations were all established by the end of the 1920s, by Erwin Schrödinger, Werner Heisenberg, Paul Dirac, and others. But no one has yet come up with a common sense explanation of what is going on.

In this remarkably clear and companionable audiobook, leading complex systems scientist Melanie Mitchell provides an intimate tour of the sciences of complexity, a broad set of efforts that seek to explain how large-scale complex, organized, and adaptive behavior can emerge from simple interactions among myriad individuals.

Nothing in the universe is more complex than life. Throughout the skies, in oceans, and across lands, life is endlessly on the move. In its myriad forms—from cells to human beings, social structures, and ecosystems—life is open-ended, evolving, unpredictable, yet adaptive and self-sustaining. Complexity theory addresses the mysteries that animate science, philosophy, and metaphysics: how this teeming array of existence, from the infinitesimal to the infinite, is in fact a seamless living whole and what our place, as conscious beings, is within it.

The Idea of the World offers a grounded alternative to the frenzy of unrestrained abstractions and unexamined assumptions in philosophy and science today. This book examines what can be learned about the nature of reality based on conceptual parsimony, straightforward logic, and empirical evidence from fields as diverse as physics and neuroscience. It compiles an overarching case for idealism - the notion that reality is essentially mental - from 10 original articles the author has previously published in leading academic journals.

An exhilarating tour of the contemporary quantum landscape, Beyond Weird is a book about what quantum physics really means - and what it doesn't. Science writer Philip Ball offers an up-to-date, accessible account of the quest to come to grips with the most fundamental theory of physical reality, and to explain how its counterintuitive principles underpin the world we experience.

Already internationally acclaimed for his elegant, lucid writing on the most challenging notions in modern physics, Sean Carroll is emerging as one of the greatest humanist thinkers of his generation as he brings his extraordinary intellect to bear not only on the Higgs boson and extra dimensions but now also on our deepest personal questions. Where are we? Who are we? Are our emotions, our beliefs, and our hopes and dreams ultimately meaningless out there in the void?

In this audiobook, The Human Odyssey, we explore the evolution of those characteristics that make us human. The first section looks at our family tree and why some branches survived and not others. Swings in climate are emerging as a factor in what traits succeeded and failed; meanwhile, DNA analyses show that Homo sapiens interbred with other human species, which played a key role in our survival.

At once a spirited defense of Darwinian explanations of biology and an elegant primer on evolution for the general listener, What Evolution Is poses the questions at the heart of evolutionary theory and considers how our improved understanding of evolution has affected the viewpoints and values of modern man.

In a rarified world of scientific research, a revolution has been brewing. Its activists are not anarchists, but rather Nobel Laureates in physics and economics and pony-tailed graduates, mathematicians, and computer scientists from all over the world. They have formed an iconoclastic think-tank and their radical idea is to create a new science: complexity. They want to know how a primordial soup of simple molecules managed to turn itself into the first living cell--and what the origin of life some four billion years ago can tell us about the process of technological innovation today.