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Hacking the Code of Life
- How Gene Editing Will Rewrite Our Futures
- Narrated by: Karen Cass
- Length: 4 hrs and 41 mins
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Publisher's summary
Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year.
But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.
But is it ethical to change the genetic material of organisms in a way that might be passed on to future generations? If a person is suffering from a lethal genetic disease, is it even more unethical to deny them this option? Who controls the application of this technology, when it makes "biohacking" - perhaps of one’s own genome - a real possibility?
Nessa Carey’s book is a thrilling and timely snapshot of a technology that will radically alter our futures.
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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The Compatibility Gene
- How Our Bodies Fight Disease, Attract Others, and Define Our Selves
- By: Daniel M. Davis
- Narrated by: Christopher Grove
- Length: 7 hrs and 48 mins
- Unabridged
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Most of the 25,000 genes we possess are the same for all of us. Compatibility genes are those that vary most from person to person and give each of us a unique molecular signature. These genes determine both the extent to which we are susceptible to a vast range of illnesses and the different ways each of us fights disease.
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If interested in medicine, got to read
- By Howard Sterling on 06-29-16
By: Daniel M. Davis
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10% Human
- How Your Body's Microbes Hold the Key to Health and Happiness
- By: Alanna Collen
- Narrated by: Cat Gould
- Length: 12 hrs and 45 mins
- Unabridged
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You are just 10% human. For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony. Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.
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Must read for anyone that wants to be healthy
- By T. Kalinowski on 06-05-21
By: Alanna Collen
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The Deeper Genome
- Why There Is More to the Human Genome than Meets the Eye
- By: John Parrington
- Narrated by: John Lee
- Length: 9 hrs
- Unabridged
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Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.
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Great Scientific Writing/ Wrong Narrator
- By Richard on 11-24-15
By: John Parrington
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- By: Kevin Davies
- Narrated by: Kevin Davies
- Length: 16 hrs and 17 mins
- Unabridged
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Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- By Samuel Finlayson on 01-25-21
By: Kevin Davies
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Sicker, Fatter, Poorer
- The Urgent Threat of Hormone-Disrupting Chemicals on Our Health and Future . . . and What We Can Do About It
- By: Leonardo Trasande MD MPP
- Narrated by: Leonardo Trasande MD MPP
- Length: 6 hrs and 44 mins
- Unabridged
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Lurking in our homes, hiding in our offices, and polluting the air we breathe is something sinister. Something we’ve turned a blind eye to for far too long. Dr. Leonardo Trasande, a pediatrician, professor, and world-renowned researcher, tells the story of how our everyday surroundings are making us sicker, fatter, and poorer. Through a blend of narrative, scientific detective work, and concrete information about the connections between chemicals and disease, he reveals what we can do to protect ourselves and our families in the short-term, and how we can help bring the change we deserve.
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The Must Read Book of 2019 is here early on Audio!
- By Ryan S on 12-21-18
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p53: The Gene That Cracked the Cancer Code
- By: Sue Armstrong
- Narrated by: Elizabeth Jasicki
- Length: 9 hrs and 55 mins
- Unabridged
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p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.
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Excellent story! Unfortunate narration at start
- By Adriana on 12-25-14
By: Sue Armstrong
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Denialism
- How Irrational Thinking Hinders Scientific Progress, Harms the Planet, and Threatens Our Lives
- By: Michael Specter
- Narrated by: Richard Poe
- Length: 8 hrs and 33 mins
- Unabridged
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New Yorker staff writer Michael Specter has twice won the Global Health Council’s Excellence in Media Award, as well as the Science Journalism Award from the American Association for the Advancement of Science. In Denialism, he fervently argues that people are turning away from new technologies and engaging in a kind of magical thinking that is hindering scientific progress.
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A compelling read
- By S on 05-17-11
By: Michael Specter
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The Gene
- An Intimate History
- By: Siddhartha Mukherjee
- Narrated by: Dennis Boutsikaris
- Length: 19 hrs and 22 mins
- Unabridged
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The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.
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It's a Wonderful Book
- By JKC on 06-02-16
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The Cancer Chronicles
- Unlocking Medicine's Deepest Mystery
- By: George Johnson
- Narrated by: Arthur Morey
- Length: 8 hrs and 19 mins
- Unabridged
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When the woman he loved was diagnosed with a metastatic cancer, science writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is a revolution under way - an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease.
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A quick read - hard to put down
- By Digital Dilema on 09-06-13
By: George Johnson
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Pandora's Seed
- The Unforeseen Cost of Civilization
- By: Spencer Wells
- Narrated by: Spencer Wells
- Length: 6 hrs and 40 mins
- Unabridged
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This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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Short and unfocused, but often quite interesting.
- By Alan on 06-23-10
By: Spencer Wells
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The Truth About Cancer
- By: Ty M. Bollinger
- Narrated by: Ty M. Bollinger
- Length: 9 hrs and 11 mins
- Unabridged
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One out of three women alive today, and one out of two men, will face a cancer diagnosis, according to the World Health Organization. Ty Bollinger takes this personally: in the course of a decade, he says, "I lost my entire family to cancer. I don't believe I had to lose them." The Truth about Cancer has been written for one simple reason: to share the knowledge we need to protect ourselves, treat ourselves, and in some cases save our lives or the lives of those we love.
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save a life with this valuable information.
- By edwin matias on 12-30-16
By: Ty M. Bollinger
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Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the 20-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.
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Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.
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biochemistry+autobiography+science politics
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For decades after the identification of the structure of DNA, scientists focused only on genes, the regions of the genome that contain codes for the production of proteins. Other regions that make up 98 percent of the human genome were dismissed as "junk," sequences that serve no purpose. But researchers have recently discovered variations and modulations in this junk DNA that are involved with a number of intractable diseases. Junk DNA can play vital and unanticipated roles in the control of gene expression, from fine-tuning individual genes to switching off entire chromosomes.
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- By Irina Bataeva on 02-15-19
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- A Doctor's Quest to Understand, Treat, and Prevent Cardiovascular Disease
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What listeners say about Hacking the Code of Life
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Philip Savva
- 04-30-22
Bang ! Crack ! Swashbucklers will save us ..
Info-audicted, finally someone raising the roof. Here's the arthritis cure & how it is done.
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- Joel
- 02-23-23
Not captivating nor intriguing story at all.
Content is good, updated, talks about innovation and in depth in the topic. However, Not captivating nor intriguing story at all.
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- Stephen H
- 01-20-24
A brief dip of the toe
I cannot say that this was bad, but it was not exactly what I expected. In 4 2/3 hours, the book manages a brief overview of gene editing and its potential impacts on life in the future.
After a brief introduction, the author focuses on gene editing using CRISPR; no surprise here. She does not really say much about how CRISPR works, and spends more time on patent battles than on the scientific details. While she discusses some of the ways genes have been edited or could be edited, and the purpose of such changes, this is really quite perfunctory.
The book simply seems to lack a clear purpose and focus, and so one bounces from one idea to the next without an overarching narrative. It was okay, but not great.
The narrator was good, with no major missteps.
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- Linda S.
- 02-08-23
Enjoyable listen
As a farm wife I am increasingly shocked by the general publics ignorance about “GMOs”. I appreciate this opportunity to educate myself further about this very important topic.
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- RickyF
- 03-31-23
okay book
lots of info here. if this topic is unfamiliar then it is worth reading.
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- A. Toomey
- 06-18-20
Decent Overview. Could lose sarcasm.
This book starts out with a lot of snark and sarcasm. I'm assuming the intention is to provide humor, but for me it was too thickly laid on for a science book even one meant for the mainstream. Thankfully, by chapter two it does thin down to the occasional comment or jab at this group or that situation.
Overall the content generally lines up with what I know of the field, though I'm no expert. At times she does raise some interesting questions and conundrums which will need to be addressed as the science moves forward. If you're looking for a broad overview of the field this succeeds in that regard, though as others have noted, with a field moving along so quickly how long this information remains current is anyone's guess.
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5 people found this helpful
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- Donita
- 02-15-23
Good layman insight to complex issue
I have enormously high hopes for CRISPR for personal reasons & I want the technology to hurry up and get here, but this book opened my eyes to the known unknowns & made me aware of unintended consequences. I have great respect for the scientific community that is working so hard to try to help what has been beyond help. I thought this book did a good job of illustrating all aspects of this miraculous leap forward in our collective knowledge.
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- sct
- 07-04-19
Great survey on the state of the art of genetics
I listened this book in rapid succession after 'The Gene' by Siddhartha Mukherjee and Nessa''s previous book "The Epigentics Revolution". I'd highly recommend this trio if you want to get a good grounder on this topic.
I felt that the book did a great job reviewing the state of the art of this area of science. Not only the science, but also gave insights into the regulatory difficulties, the people behind the science and she even touched on some of the ethical issues. She succeeded in being balanced and even - i.e., no moral preening that was present in other books on this topic. Probably the most sensationalistic part of the book is the title - but authors sometimes don't get to choose this.
I saw another post about the audio being bad - I had no such complaints.
The only fear I have about this book is that because the science is moving so quickly, it may have a short shelf life. So...listen to it now!
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4 people found this helpful
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- Rick B
- 05-22-21
A New World
This is an excellent listen from Audible as it reflects on the history of an emerging technology that has the power to change the world. The narration by Karen Cass is perfect. If you enjoy learning and appreciate the value of truth, then I believe that this investment will not disappoint you. The near future is ours to control. Will we do it responsibly or change our species by mistake. There are very deep possibilities within Gene editing. We could help feed the hungry, prevent disease and stop the incredible pain that some people must feel just to be alive. There is so much we could do to make positive change, but the possibility for negative change is beyond our understanding. I highly recommend this book, The narrator has a very English accent, I think that adds to the over all value as the listener is more inclined to listen carefully to the message. 5 Stars all the way!
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2 people found this helpful
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- Pete D
- 10-14-19
Wonderfull Book
Well done so a layman can understand. Very current information in a fast moving field.
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1 person found this helpful